Search Results - "Hiroki NAGAI"

Visualization of the working fluid in a flat-plate pulsating heat pipe by neutron radiography by Yasuda, Yosuke, Nabeshima, Fumika, Horiuchi, Keisuke, Nagai, Hiroki

“…•Behaviors of the working fluid in a flat-plate pulsating heat pipe (PHP) were visualized by neutron radiography.•The initial distribution of the working fluid…”
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Optimal management of immune-related adverse events resulting from treatment with immune checkpoint inhibitors: a review and update by Nagai, Hiroki, Muto, Manabu

“…Over the last two decades, molecular-targeted agents have become mainstream treatment for many types of malignancies and have improved the overall survival of…”
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Selective autophagy tolerates symbiotic bacteria in the Drosophila intestine by Nagai, Hiroki, Yano, Tamaki

“…Intestinal epithelium functions as a barrier to protect the host from environmental microbes. Defects in macroautophagy/autophagy combined with intestinal…”
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Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex by Kim, Hyunmin, Kubori, Tomoko, Yamazaki, Kohei, Kwak, Mi-Jeong, Park, Suk-Youl, Nagai, Hiroki, Vogel, Joseph P., Oh, Byung-Ha

“…The Legionella pneumophila Dot/Icm type IVB secretion system (T4BSS) is extremely versatile, translocating ~300 effector proteins into host cells. This…”
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Recent advances in structural studies of the Legionella pneumophila Dot/Icm type IV secretion system by Kitao, Tomoe, Kubori, Tomoko, Nagai, Hiroki

“…The intracellular bacterial pathogen Legionella pneumophila utilizes the Dot/Icm type IV secretion system to translocate approximately 300 effector proteins to…”
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cntTSP visualization technique for rotating blade surface flow at low Reynolds number by Ikami, Tsubasa, Nishimura, Ren, Nagai, Hiroki

“…Research and development of aircraft with rotating wings at low Reynolds numbers have received much attention. This study proposes using a carbon nanotube…”
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Structural Basis of Ubiquitin Recognition by a Bacterial Ovarian Tumor Deubiquitinase LotA by Takekawa, Norihiro, Kubori, Tomoko, Iwai, Tomoya, Nagai, Hiroki, Imada, Katsumi

“…Pathogenic bacteria have acquired a vast array of eukaryotic-protein-like proteins via intimate interaction with host cells. Bacterial effector proteins that…”
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Study on thermal cycle in oscillating heat pipes by numerical analysis by Daimaru, Takurou, Yoshida, Shuhei, Nagai, Hiroki

“…•We developed a one-dimensional model to reproduce thermohydrodynamic in OHPs.•The numerical results revealed pressure propagation within the OHP.•The…”
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Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine by Nagai, Hiroki, Tatara, Hiroshi, Tanaka-Furuhashi, Kyoko, Kurata, Shoichiro, Yano, Tamaki

“…Homeostasis of intestinal epithelia is maintained by coordination of the proper rate of regeneration by stem cell division with the rate of cell loss…”
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Legionella metaeffector exploits host proteasome to temporally regulate cognate effector by Kubori, Tomoko, Shinzawa, Naoaki, Kanuka, Hirotaka, Nagai, Hiroki

“…Pathogen-associated secretion systems translocate numerous effector proteins into eukaryotic host cells to coordinate cellular processes important for…”
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Influence of Formulations on Characteristics of Ruthenium-Based Temperature-Sensitive Paints by Ikami, Tsubasa, Fujita, Koji, Nagai, Hiroki

“…Temperature-sensitive paint (TSP) can optically measure a global temperature distribution using a thermal quenching of dye molecules. The TSP measurement is…”
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Investigation of Formulations on Pyrene-Based Anodized-Aluminum Pressure-Sensitive Paints for Supersonic Phenomena by Yomo, Kazuma, Ikami, Tsubasa, Fujita, Koji, Nagai, Hiroki

“…Pressure-sensitive paint (PSP) is an optical sensor that can measure global pressure distribution by using the oxygen quenching of dye molecules. In…”
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Numerical study of temperature oscillation in loop heat pipe by Adachi, Takuya, Fujita, Koji, Nagai, Hiroki

“…•Once a two-phase flow is generated in the liquid line, temperature oscillation occurs.•A low reservoir temperature leads to a two-phase flow in the liquid…”
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Synthetic engineering and biological containment of bacteriophages by Mitsunaka, Shoichi, Yamazaki, Kohei, Pramono, Ajeng K, Ikeuchi, Megumi, Kitao, Tomoe, Ohara, Naoya, Kubori, Tomoko, Nagai, Hiroki, Ando, Hiroki

“…The serious threats posed by drug-resistant bacterial infections and recent developments in synthetic biology have fueled a growing interest in genetically…”
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Isolation of the Dot/Icm Type IV Secretion System Core Complex from Legionella pneumophila by Kubori, Tomoko, Nagai, Hiroki

“…Legionella utilizes specialized protein secretion machinery called the type IV secretion system encoded by dot/icm genes to modulate host cellular systems. We…”
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Joint parameters for strain-based geometrically nonlinear beam formulation: Multibody analysis and experiment by Otsuka, Keisuke, Dong, Shuonan, Fujita, Koji, Nagai, Hiroki, Makihara, Kanjuro

“…•Folding wing aircraft and offshore wind turbine are focused on.•An efficient dynamic simulation method is developed.•Experimental validation using wind tunnel…”
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Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer by Kobayashi, Yoshihisa, Azuma, Koichi, Nagai, Hiroki, Kim, Young Hak, Togashi, Yosuke, Sesumi, Yuichi, Chiba, Masato, Shimoji, Masaki, Sato, Katsuaki, Tomizawa, Kenji, Takemoto, Toshiki, Nishio, Kazuto, Mitsudomi, Tetsuya

“…Lung cancers harboring common EGFR mutations respond to EGFR tyrosine kinase inhibitors (TKI). We previously reported that tumors with exon 18 mutations are…”
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Divergence of Legionella Effectors Reversing Conventional and Unconventional Ubiquitination by Kitao, Tomoe, Nagai, Hiroki, Kubori, Tomoko

“…The intracellular bacterial pathogen employs bacteria-derived effector proteins in a variety of functions to exploit host cellular systems. The ubiquitination…”
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Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics by Kubori, Tomoko, Arasaki, Kohei, Oide, Hiromu, Kitao, Tomoe, Nagai, Hiroki

“…Rab GTPases are representative targets of manipulation by intracellular bacterial pathogens for hijacking membrane trafficking. recruits many Rab GTPases to…”
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Morphokinetic analysis of pronuclei using time-lapse cinematography in bovine zygotes by Suzuki, Ryosuke, Okada, Mai, Nagai, Hiroki, Kobayashi, Junichi, Sugimura, Satoshi

“…The morphokinetics of pronuclei (PN) are considered crucial factors affecting embryogenesis in mammals. Whereas, since bovine zygotes contain a large number of…”
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