Search Results - "Hirohashi, Y"
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p78 MCRS1 forms a complex with centrosomal protein Nde1 and is essential for cell viability
Published in Oncogene (10-08-2006)“…The centrosome, an organelle that functions as the major microtubule-organizing center, plays an essential role in the formation of the mitotic spindle and…”
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Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylation
Published in Oncogene (05-10-2006)“…The centrosome modulates spindle formation and plays a critical role in guiding proper segregation of chromosomes during cell division. Centrosome aberrations,…”
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Preferential expression of cancer/testis genes in cancer stem-like cells: proposal of a novel sub-category, cancer/testis/stem gene
Published in Tissue antigens (01-06-2013)“…Cancer/testis (CT) antigens encoded by CT genes are immunogenic antigens, and the expression of CT gene is strictly restricted to only the testis among mature…”
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34P Cocktail peptide vaccines targeting cancer stem cells for enhanced therapeutic efficacy in oral cancers
Published in ESMO open (01-02-2024)Get full text
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Differential gene expression screening between parental and highly metastatic pancreatic cancer variants using a DNA microarray
Published in Journal of experimental & clinical cancer research (01-06-2003)“…To clarify the difference in genes expressed in hematogenous metastasis and peritoneal dissemination, a broad analysis of differential gene expression analysis…”
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Possible Pseudo-progression of Non-small Cell Lung Carcinoma in a Patient With Clinical Hyper-progression Associated With Trousseau Syndrome Who Was Treated With Pembrolizumab: A Case Report
Published in Anticancer research (01-07-2021)“…Background/Aim: Immune checkpoint inhibitors (ICIs), including nivolumab and pembrolizumab, have recently been shown to have clinical benefits in patients with…”
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Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
Published in Cancer research (Chicago, Ill.) (01-12-2005)“…Survivin, a member of the inhibitor of apoptosis protein family, is widely expressed in a variety of human cancer tissues. Survivin inhibits activation of…”
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Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair-deficient colorectal cancer tissue
Published in JCI insight (22-07-2021)“…Although CD8+ T cells recognize neoantigens that arise from somatic mutations in cancer, only a small fraction of nonsynonymous mutations give rise to…”
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Cancer Stem Cell Targeting Immunotherapy
Published in Annals of oncology (01-10-2012)Get full text
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