Search Results - "Hirobe, Ryuta"

Epigallocatechin gallate induces a hepatospecific decrease in the CYP3A expression level by altering intestinal flora by Ikarashi, Nobutomo, Ogawa, Sosuke, Hirobe, Ryuta, Kon, Risako, Kusunoki, Yoshiki, Yamashita, Marin, Mizukami, Nanaho, Kaneko, Miho, Wakui, Nobuyuki, Machida, Yoshiaki, Sugiyama, Kiyoshi

“…In previous studies, we showed that a high-dose intake of green tea polyphenol (GP) induced a hepatospecific decrease in the expression and activity of the…”
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Effects of Menthol on the Pharmacokinetics of Triazolam and Phenytoin by Hoshino, Motohiro, Ikarashi, Nobutomo, Hirobe, Ryuta, Hayashi, Mami, Hiraoka, Hironori, Yokobori, Kohsuke, Ochiai, Takumi, Kusunoki, Yoshiki, Kon, Risako, Tajima, Masataka, Ochiai, Wataru, Sugiyama, Kiyoshi

“…We have previously shown that menthol attenuates the anticoagulant effect of warfarin by increasing the expression levels of CYP3A and CYP2C in the liver. This…”
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High-dose green tea polyphenol intake decreases CYP3A expression in a liver-specific manner with increases in blood substrate drug concentrations by Ikarashi, Nobutomo, Ogawa, Sosuke, Hirobe, Ryuta, Kusunoki, Yoshiki, Kon, Risako, Ochiai, Wataru, Sugiyama, Kiyoshi

“…In recent years, the intake of functional foods containing high-doses of green tea polyphenols (GP) has been increasing. In this study, the long-term safety of…”
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