Evaluation of sulfobetaine-type polymer resin as an SPE adsorbent in the analysis of trace tetracycline antibiotics in honey

Evaluation of sulfobetaine-type polymer resin as an SPE adsorbent in the analysis of trace tetracycline antibiotics in honey

A new sulfobetaine polymer resin SPE method combined with HPLC-MS/MS for the determination of tetracycline (TC) antibiotics residues from honey samples is presented. The sulfobetaine resin was synthesized and was packed into a syringe-type tube, which served as the SPE cartridge for selective adsorp...

Full description

Saved in:
Bibliographic Details
Published in:Journal of separation science Vol. 32; no. 21; pp. 3591 - 3595
Main Authors: Tsukamoto, Tomoyasu, Yasuma, Mari, Yamamoto, Atsushi, Hirayama, Kayo, Kihou, Takafumi, Kodama, Shuji, Inoue, Yoshinori
Format: Journal Article
Language:English
Published: Weinheim Wiley-VCH Verlag 01-11-2009
WILEY-VCH Verlag
WILEY‐VCH Verlag
Subjects:
Acetonitrile
Adsorption
Anti-Bacterial Agents - analysis
Antibiotics
Betaine - analogs & derivatives
Betaine - chemistry
Cartridges
Chromatography, Liquid
Honey
Honey - analysis
Polymers
Polymers - chemistry
Recovery
Reference Standards
Resins
SPE
Sulfobetaine polymer resin
Tandem Mass Spectrometry
Tetracycline - analysis
Tetracycline antibiotics
Tetracyclines
Zwitter ion
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new sulfobetaine polymer resin SPE method combined with HPLC-MS/MS for the determination of tetracycline (TC) antibiotics residues from honey samples is presented. The sulfobetaine resin was synthesized and was packed into a syringe-type tube, which served as the SPE cartridge for selective adsorption of TCs. TCs were quantitatively adsorbed on the sulfobetaine cartridge, when the loading solvent was 95% v/v acetonitrile solution, and TCs adsorbed were not eluted by aqueous acetonitrile washing solution. TFA aqueous solution was used for eluting the adsorbed TCs. The proposed SPE method has been applied to the determination of TCs in honey samples. The recoveries of TCs spiked in honey samples ranged from 70 to 80%. Reduction of the recoveries might be derived from low solubility of TCs in acetonitrile. Compared with other SPE resins, this resin was superior in terms of selectivity with simple pretreatment.
Bibliography:http://dx.doi.org/10.1002/jssc.200900520
istex:54DD3D5A187102F0F69E60B51497D56ABF978DA5
ark:/67375/WNG-0S3X0KWK-B
ArticleID:JSSC200900520
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:1615-9306
1615-9314
DOI:10.1002/jssc.200900520