Search Results - "Hirata, Tomoko"

A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies by Kohda, Masakazu, Tokuzawa, Yoshimi, Kishita, Yoshihito, Nyuzuki, Hiromi, Moriyama, Yohsuke, Mizuno, Yosuke, Hirata, Tomoko, Yatsuka, Yukiko, Yamashita-Sugahara, Yzumi, Nakachi, Yutaka, Kato, Hidemasa, Okuda, Akihiko, Tamaru, Shunsuke, Borna, Nurun Nahar, Banshoya, Kengo, Aigaki, Toshiro, Sato-Miyata, Yukiko, Ohnuma, Kohei, Suzuki, Tsutomu, Nagao, Asuteka, Maehata, Hazuki, Matsuda, Fumihiko, Higasa, Koichiro, Nagasaki, Masao, Yasuda, Jun, Yamamoto, Masayuki, Fushimi, Takuya, Shimura, Masaru, Kaiho-Ichimoto, Keiko, Harashima, Hiroko, Yamazaki, Taro, Mori, Masato, Murayama, Kei, Ohtake, Akira, Okazaki, Yasushi

“…Mitochondrial disorders have the highest incidence among congenital metabolic disorders characterized by biochemical respiratory chain complex deficiencies. It…”
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Long-term prognosis and genetic background of cardiomyopathy in 223 pediatric mitochondrial disease patients by Imai-Okazaki, Atsuko, Matsunaga, Ayako, Yatsuka, Yukiko, Nitta, Kazuhiro R., Kishita, Yoshihito, Sugiura, Ayumu, Sugiyama, Yohei, Fushimi, Takuya, Shimura, Masaru, Ichimoto, Keiko, Tajika, Makiko, Ogawa-Tominaga, Minako, Ebihara, Tomohiro, Matsuhashi, Tetsuro, Tsuruoka, Tomoko, Kohda, Masakazu, Hirata, Tomoko, Harashima, Hiroko, Nojiri, Shuko, Takeda, Atsuhito, Nakaya, Akihiro, Kogaki, Shigetoyo, Sakata, Yasushi, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi

“…Cardiomyopathy is a risk factor for poor prognosis in pediatric patients with mitochondrial disease. However, other risk factors including genetic factors…”
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Barth Syndrome: Different Approaches to Diagnosis by Imai-Okazaki, Atsuko, Kishita, Yoshihito, Kohda, Masakazu, Yatsuka, Yukiko, Hirata, Tomoko, Mizuno, Yosuke, Harashima, Hiroko, Hirono, Keiichi, Ichida, Fukiko, Noguchi, Atsuko, Yoshida, Masayuki, Tokorodani, Chiho, Nishiuchi, Ritsuo, Takeda, Atsuhito, Nakaya, Akihiro, Sakata, Yasushi, Murayama, Kei, Ohtake, Akira, Okazaki, Yasushi

“…The diagnosis of Barth syndrome is challenging owing to the wide phenotypic spectrum with allelic heterogeneity. Here we report 3 cases of Barth syndrome with…”
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HDR‐del: A tool based on Hamming distance for prioritizing pathogenic chromosomal deletions in exome sequencing by Imai‐Okazaki, Atsuko, Kohda, Masakazu, Kobayashi, Kaori, Hirata, Tomoko, Sakata, Yasushi, Murayama, Kei, Ohtake, Akira, Okazaki, Yasushi, Nakaya, Akihiro, Ott, Jurg

“…High‐density oligonucleotide arrays have widely been used to detect pathogenic chromosomal deletions. In addition to high‐density oligonucleotide arrays,…”
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Biallelic GGGCC repeat expansion leading to NAXE-related mitochondrial encephalopathy by Ozaki, Kokoro, Yatsuka, Yukiko, Oyazato, Yoshinobu, Nishiyama, Atsushi, Nitta, Kazuhiro R., Kishita, Yoshihito, Fushimi, Takuya, Shimura, Masaru, Noma, Shohei, Sugiyama, Yohei, Tagami, Michihira, Fukunaga, Moe, Kinoshita, Hiroko, Hirata, Tomoko, Suda, Wataru, Murakawa, Yasuhiro, Carninci, Piero, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi

“…Repeat expansions cause at least 50 hereditary disorders, including Friedreich ataxia and other diseases known to cause mitochondrial dysfunction. We…”
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Preventive Effect of TRPV1 Agonists Capsaicin and Resiniferatoxin on Ischemia/Reperfusion-induced Renal Injury in Rats by Ueda, Kyoko, Tsuji, Fumio, Hirata, Tomoko, Takaoka, Masanori, Matsumura, Yasuo

“…We evaluated the effect of capsaicin, one of the transient receptor potential vanilloid receptor 1 (TRPV1) agonists, on ischemic acute renal failure (ARF) in…”
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Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies by Kohda, Masakazu, Kumamoto, Kensuke, Eguchi, Hidetaka, Hirata, Tomoko, Tada, Yuhki, Tanakaya, Kohji, Akagi, Kiwamu, Takenoshita, Seiichi, Iwama, Takeo, Ishida, Hideyuki, Okazaki, Yasushi

“…Genetic testing for hereditary colorectal polyposis/cancers has become increasingly important. Therefore, the development of a timesaving diagnostic platform…”
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Preventive effect of SA13353 [1-[2-(1-adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea], a novel transient receptor potential vanilloid 1 agonist, on ischemia/reperfusion-induced renal injury in rats by Ueda, Kyoko, Tsuji, Fumio, Hirata, Tomoko, Ueda, Kenji, Murai, Masaaki, Aono, Hiroyuki, Takaoka, Masanori, Matsumura, Yasuo

“…Tumor necrosis factor (TNF)-alpha plays a crucial role in the pathogenesis of ischemia/reperfusion-induced renal injury. We demonstrated recently that the…”
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Characterization of putative tryptophan monooxygenase from Ralstonia solanasearum by Kurosawa, Nami, Hirata, Tomoko, Suzuki, Haruo

“…The amino-acid sequence of a putative tryptophan monooxygenase (PTMO) from Ralstonia solanacearum is homologous with that of proenzyme (proPAO) of l-Phe…”
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HUMAN FAMSD-BASE: High Quality Protein Structure Model Database for the Human Genome Using the FAMSD Homology Modeling Method by Kanou, Kazuhiko, Hirata, Tomoko, Iwadate, Mitsuo, Terashi, Genki, Umeyama, Hideaki, Takeda-Shitaka, Mayuko

“…Almost all proteins express their biological functions through the structural conformation of their specific amino acid sequences. Therefore, acquiring the…”
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FAMSD: A Powerful Protein Modeling Platform that Combines Alignment Methods, Homology Modeling, 3D Structure Quality Estimation and Molecular Dynamics by Kanou, Kazuhiko, Iwadate, Mitsuo, Hirata, Tomoko, Terashi, Genki, Umeyama, Hideaki, Takeda-Shitaka, Mayuko

“…The prediction of a protein three-dimensional (3D) structure is one of the most important challenges in computational structural biology. We have developed an…”
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New Protein Structure Model Evaluation Methods That Include a Side-Chain Consensus Score for the Protein Modeling by Kanou, Kazuhiko, Hirata, Tomoko, Terashi, Genki, Umeyama, Hideaki, Takeda-Shitaka, Mayuko

“…Selecting the best quality model from a set of predicted structures is one of the most important aspects of protein structure prediction. We have developed…”
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Trends in admission to a new palliative care unit from home and subjects for the future by Sato, Akiko, Hirata, Tomoko, Hayashi, Eriko, Sasaki, Takumi, Fukano, Fumiyasu, Kusakabe, Akihiko

“…We investigated the trend in admission to new a palliative care unit (PCU) over 9 months. We observed a significant difference in the length of PCU stay…”
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Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress by Hayashi, Tetsuya, Yamashita, Chika, Matsumoto, Chika, Kwak, Chol-Jun, Fujii, Kiwako, Hirata, Tomoko, Miyamura, Masatoshi, Mori, Tatsuhiko, Ukimura, Akira, Okada, Yoshikatsu, Matsumura, Yasuo, Kitaura, Yasushi

“…Intermittent hypoxia due to sleep apnea syndrome is associated with cardiovascular diseases. However, the precise mechanisms by which intermittent hypoxic…”
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Usefulness of a manual on physician behavior at the time of death confirmation by Kusakabe, Akihiko, Otani, Yoichi, Kakuto, Atsumi, Iwami, Kanako, Sato, Akiko, Hirata, Tomoko, Yokoi, Nobuto, Tsuzaki, Yoko, Yagi, Hiroaki, Tamura, Yoichi, Okita, Masato, Inamori, Masahiko

“…The behavior of a physician when confirming the death of a patient is thought to greatly affect the bereaved family. The required aspects of a physician's…”
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Cardiomyopathy in children with mitochondrial disease: Prognosis and genetic background by Imai-Okazaki, Atsuko, Kishita, Yoshihito, Kohda, Masakazu, Mizuno, Yosuke, Fushimi, Takuya, Matsunaga, Ayako, Yatsuka, Yukiko, Hirata, Tomoko, Harashima, Hiroko, Takeda, Atsuhito, Nakaya, Akihiro, Sakata, Yasushi, Kogaki, Shigetoyo, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi

“…Cardiomyopathy is a reported indicator of poor prognosis in children with mitochondrial disease. However, the association between prognosis and the genetic…”
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New Protein Structure Model Evaluation Methods That Include a Side-Chain Consensus Score for the Protein Modeling by Kazuhiko KANOUa, Tomoko HIRATAa, Genki TERASHIa, Hideaki UMEYAMAa, b, Mayuko TAKEDA-SHITAKAa

“…Selecting the best quality model from a set of predicted structures is one of the most important aspects of protein structure prediction. We have developed…”
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FAMSD: A Powerful Protein Modeling Platform that Combines Alignment Methods, Homology Modeling, 3D Structure Quality Estimation and Molecular Dynamics by Kazuhiko KANOUa, Mitsuo IWADATEb, Tomoko HIRATAa, Genki TERASHIa, Hideaki UMEYAMAa, Mayuko TAKEDA-SHITAKAa

“…The prediction of a protein three-dimensional (3D) structure is one of the most important challenges in computational structural biology. We have developed an…”
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Rapidly progressive infantile cardiomyopathy with mitochondrial respiratory chain complex V deficiency due to loss of ATPase 6 and 8 protein by Imai, Atsuko, Fujita, Shuhei, Kishita, Yoshihito, Kohda, Masakazu, Tokuzawa, Yoshimi, Hirata, Tomoko, Mizuno, Yosuke, Harashima, Hiroko, Nakaya, Akihiro, Sakata, Yasushi, Takeda, Atsuhito, Mori, Masato, Murayama, Kei, Ohtake, Akira, Okazaki, Yasushi

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Improvement in the awareness of palliative care nursing using STAS-J in an acute care hospital by Shirakawa, Tsuyoshi, Hikage, Keiko, Akino, Terumi, Hirata, Tomoko, Shigematsu, HIroko, Nagaie, Tomoko, Ariyama, Hiroshi, Kusaba, Hitoshi, Akashi, Koichi, Baba, Eishi

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