Search Results - "Hirata, M. H."

Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women by Barbosa, P.R, Stabler, S.P, Machado, A.LK, Braga, R.C, Hirata, R.D.C, Hirata, M.H, Sampaio-Neto, L.F, Allen, R.H, Guerra-Shinohara, E.M

“…Objectives: To examine the association between methylenetetrahydrofolate reductase (MTHFR) (C677T and A1298C), methionine synthase (MTR) A2756G and methionine…”
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Genetic susceptibility in pharmacodynamic and pharmacokinetic pathways underlying drug-induced arrhythmia and sudden unexplained deaths by Martinez-Matilla, M, Blanco-Verea, A, Santori, M, Ansede-Bermejo, J, Ramos-Luis, E, Gil, R, Bermejo, AM, Lotufo-Neto, F, Hirata, MH, Brisighelli, F, Paramo, M, Carracedo, A, Brion, M

“…AbstractDrug-induced arrhythmia is an adverse drug reaction that can be potentially fatal since it is mostly related to drug-induced QT prolongation, a known…”
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Genetic and non-genetic factors that increase the risk of non-syndromic cleft lip and/or palate development by Bezerra, JF, Oliveira, GHM, Soares, CD, Cardoso, ML, Ururahy, MAG, Neto, FPF, Lima-Neto, LG, Luchessi, AD, Silbiger, VN, Fajardo, CM, de Oliveira, SR, Almeida, M das G, Hirata, RDC, de Rezende, AA, Hirata, MH

“…Objectives We investigated the relationship between non‐syndromic cleft lip/palate (NSCLP) and polymorphisms in methylenetetrahydrofolate reductase (MTHFR),…”
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pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of Brazil by Barco, P., Cardoso, R. F., Hirata, R. D. C., Leite, C. Q. F., Pandolfi, J. R., Sato, D. N., Shikama, M. L., de Melo, F. Fiúza, Mamizuka, E. M., Campanerut, P. A. Z., Hirata, M. H.

“…Objectives: To investigate the presence of mutations in the pncA gene in 31 pyrazinamide-resistant Mycobacterium tuberculosis and 5 susceptible strains. MICs…”
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Optimized procedure for DNA isolation from fresh and cryopreserved clotted human blood useful in clinical molecular testing by SALAZAR, L. A, HIRATA, M. H, CAVALLI, S. A, MACHADO, M. O, HIRATA, R. D. C

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MSX1 gene polymorphisms in non-syndromic cleft lip and/or palate by Cardoso, ML, Bezerra, JF, Oliveira, GHM, Soares, CD, Oliveira, SR, de Souza, KSC, da Silva, HPV, Silbiger, VN, Luchessi, AD, Fajardo, CM, Hirata, RDC, Almeida, MG, Hirata, MH, Rezende, AA

“…Objective The aim of this study was to investigate the contribution of 6 polymorphic variants of the MSX1 gene in non‐syndromic cleft lip and/or palate…”
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Direct Detection of Mycobacterium bovis in Bovine Lymph Nodes by PCR by Cardoso, M.A, Cardoso, R.F, Hirata, R.D.C, Hirata, M.H, Leite, C.Q.F, Santos, A.C.B, Siqueira, V.L.D, Okano, W, Rocha, N.S, Lonardoni, M.V.C

“…Thirty-five lymph node samples were taken from animals with macroscopic lesions consistent with Mycobacterium bovis infection. The animals were identified by…”
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High baseline serum total and LDL cholesterol levels are associated with MDR1 haplotypes in Brazilian hypercholesterolemic individuals of European descent by Rodrigues, A C, Rebecchi, I M M, Bertolami, M C, Faludi, A A, Hirata, M H, Hirata, R D C

“…The MDR1 gene encodes the P-glycoprotein, an efflux transporter with broad substrate specificity. P-glycoprotein has raised great interest in pharmacogenetics…”
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Genetic population data of 12 STR loci of the PowerPlex® Y system in the state of São Paulo population (Southeast of Brazil) by Góis, C.C, Martins, J.A, Pereira, G.A, Freschi, A, Paneto, G.G, Alvarenga, V.L.S, Cicarelli, R.M.B, Hirata, M.H, Oliveira, R.N

“…Abstract Allele frequency distributions and population data for 12 Y-chromosomal short tandem repeats (STRs) included in the PowerPlex® Y Systems (Promega)…”
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Detection of MboII polymorphism at the 5' promoter region of CYP3A4 by Cavalli, S A, Hirata, M H, Hirata, R D

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Genetic variants in genes related to lipid metabolism and atherosclerosis, dyslipidemia and atorvastatin response by Rodrigues, A.C., Sobrino, B., Genvigir, F.D.V., Willrich, M.A.V., Arazi, S.S., Dorea, E.L., Bernik, M.M.S., Bertolami, M., Faludi, A.A., Brion, M.J., Carracedo, A., Hirata, M.H., Hirata, R.D.C.

“…Using candidate gene approach, we have investigated the effect of single nucleotide polymorphism (SNP) in genes related to lipid metabolism and atherosclerosis…”
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The association between the HLA-G 14-bp insertion/deletion polymorphism and type 1 diabetes by Silva, H P V, Ururahy, M A G, Souza, K S C, Loureiro, M B, Oliveira, Y M C, Oliveira, G H M, Luchessi, A D, Carvalho, K T C, Freitas, J C O C, Donadi, E A, Hirata, R D C, Almeida, M G, Arrais, R F, Hirata, M H, Rezende, A A

“…Type 1 diabetes (T1D) is a multifactorial disease that has a strong genetic component. The HLA-G is a nonclassical HLA class I locus that is associated with…”
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Seven DNA polymorphisms at the candidate genes of atherosclerosis in Brazilian women with angiographically documented coronary artery disease by Salazar, Luis A., Hirata, Mario H., Giannini, Sérgio D., Forti, Neusa, Diament, Jayme, Lima, Thais M., Hirata, Rosario D.C.

“…The possible association of genetic markers at the apolipoprotein E ( HhaI polymorphism), apolipoprotein B ( XbaI, EcoRI and Ins/Del polymorphisms), and…”
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Interferon-alpha receptor 1 mRNA expression in peripheral blood mononuclear cells is associated with response to interferon-alpha therapy of patients with chronic hepatitis C by Massirer, K B, Hirata, M H, Silva, A E B, Ferraz, M L G, Nguyen, N Y, Hirata, R D C

“…Interferon (IFN)-alpha receptor mRNA expression in liver of patients with chronic hepatitis C has been shown to be a response to IFN-alpha therapy. The…”
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Use of the polymerase chain reaction to detect Mycobacterium leprae in urine by Caleffi, K R, Hirata, R D C, Hirata, M H, Caleffi, E R, Siqueira, V L D, Cardoso, R F

“…Leprosy is an infectious disease caused by Mycobacterium leprae. The polymerase chain reaction (PCR) has been applied to detect M. leprae in different clinical…”
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Association of the apolipoprotein B gene polymorphisms with cholesterol levels and response to fluvastatin in Brazilian individuals with high risk for coronary heart disease by Guzmán, E C, Hirata, M H, Quintão, E C, Hirata, R D

“…The influence of genetic polymorphism of the apolipoprotein B on lipid metabolism and coronary heart disease (CHD) risk has been demonstrated in different…”
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Multiplex-PCR for differentiation of Mycobacterium bovis from Mycobacterium tuberculosis complex by Spositto, F L E, Campanerut, P A Z, Ghiraldi, L D, Leite, C Q F, Hirata, M H, Hirata, R D C, Siqueira, V L D, Cardoso, R Fressatti

“…We evaluated a multiplex-PCR to differentiate Mycobacterium bovis from M. tuberculosis Complex (MTC) by one step amplification based on simultaneous detection…”
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Recombinant antigen-based immuno-slot blot method for serodiagnosis of syphilis by Sato, N S, Suzuki, T, Ueda, T, Watanabe, K, Hirata, R D C, Hirata, M H

“…Three recombinant antigens of Treponema pallidum Nichols strain were fused with GST, cloned and expressed in Escherichia coli, resulting in high levels of…”
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Chlamydophila pneumonia and increased TLR4 gene expression in leukocytes are associated with acute myocardial infarction by Lima-Neto, L G, Hirata, R D C, Luchessi, A D, Silbiger, V N, Cavichioli, D, Dos Santos, E S, Sousa, A G M, Sprovieri, S R S, De Sousa Junior, E B, Dos Santos, F C P, Colombo, S, Hirata, M H

“…We investigated the relationship of the positivity for Chlamydophila pneumoniae (Cpn) and Mycoplasma pneumonia (Mpn), inflammatory and metabolic markers, and…”
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Metabolic behavior in rats of a nonprotein microemulsion resembling low‐density lipoprotein by Maranhão, Raul C., Cesar, Thais B., Pedroso‐Mariani, Suzana R., Hirata, Mario H., Mesquita, Carlos H.

“…A protein‐free microemulsion (LDE) with a lipid composition resembling that of low‐density lipoprotein (LDL) was used in metabolic studies in rats to compare…”
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