Search Results - "Hiranuma, Naozumi"
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Improved protein structure refinement guided by deep learning based accuracy estimation
Published in Nature communications (26-02-2021)“…We develop a deep learning framework (DeepAccNet) that estimates per-residue accuracy and residue-residue distance signed error in protein models and uses…”
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Journal Article -
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Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14
Published in Proteins, structure, function, and bioinformatics (01-12-2021)“…The trRosetta structure prediction method employs deep learning to generate predicted residue‐residue distance and orientation distributions from which 3D…”
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Journal Article -
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Protein Structure Accuracy Prediction with Deep Learning and Its Application to Structure Prediction and Design
Published 01-01-2022“…Understanding the rules of protein structure folding has always been one of the central goals in computational biology. Deep learning is gaining popularity in…”
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Dissertation -
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AIControl: replacing matched control experiments with machine learning improves ChIP-seq peak identification
Published in Nucleic acids research (04-06-2019)“…ChIP-seq is a technique to determine binding locations of transcription factors, which remains a central challenge in molecular biology. Current practice is to…”
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Journal Article -
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Modeling SARS‐CoV‐2 proteins in the CASP‐commons experiment
Published in Proteins, structure, function, and bioinformatics (01-12-2021)“…Critical Assessment of Structure Prediction (CASP) is an organization aimed at advancing the state of the art in computing protein structure from sequence. In…”
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Journal Article -
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Sexual ancestors generated an obligate asexual and globally dispersed clone within the model diatom species Thalassiosira pseudonana
Published in Scientific reports (12-07-2018)“…Sexual reproduction roots the eukaryotic tree of life, although its loss occurs across diverse taxa. Asexual reproduction and clonal lineages persist in these…”
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Journal Article