Search Results - "Hirano, Shuta"

Cardiac-Specific Overexpression of Sarcolipin Inhibits Sarco(Endo)Plasmic Reticulum Ca2+ATPase (SERCA2a) Activity and Impairs Cardiac Function in Mice by Asahi, Michio, Otsu, Kinya, Nakayama, Hiroyuki, Hikoso, Shungo, Takeda, Toshihiro, Gramolini, Anthony O., Trivieri, Maria G., Oudit, Gavin Y., Morita, Takashi, Kusakari, Yoichiro, Hirano, Shuta, Hongo, Kenichi, Hirotani, Shinichi, Yamaguchi, Osamu, Peterson, Alan, Backx, Peter H., Kurihara, Satoshi, Hori, Masatsugu, MacLennan, David H.

“…Sarcolipin (SLN) inhibits the cardiac sarco(endo)plasmic reticulum Ca2+ATPase (SERCA2a) by direct binding and is superinhibitory if it binds through…”
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Half-Logistic Time Constants as Inotropic and Lusitropic Indices for Four Sequential Phases of Isometric Tension Curves in Isolated Rabbit and Mouse Papillary Muscles by Mizuno, Ju, Morita, Shigeho, Otsuji, Mikiya, Arita, Hideko, Hanaoka, Kazuo, Akins, Robert E., Hirano, Shuta, Kusakari, Yoichiro, Kurihara, Satoshi

“…The waveforms of myocardial tension and left ventricular (LV) pressure curves are useful for evaluating myocardial and LV performance, and especially for…”
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Superior Logistic Model for Decay of Ca2+ Transient and Isometric Relaxation Force Curve in Rabbit and Mouse Papillary Muscles by Mizuno, Ju, Otsuji, Mikiya, Takeda, Kenji, Yamada, Yoshitsugu, Arita, Hideko, Hanaoka, Kazuo, Hirano, Shuta, Kusakari, Yoichiro, Kurihara, Satoshi

“…A decrease in myocardial intracellular calcium concentration ([Ca2+]i) precedes relaxation, and a monoexponential function is typically used for fitting the…”
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Characterization of intracellular Ca2+ transient by the hybrid logistic function in aequorin-injected rabbit and mouse papillary muscles by Mizuno, Ju, Otsuji, Mikiya, Arita, Hideko, Hanaoka, Kazuo, Morita, Shigeho, Akins, Robert, Hirano, Shuta, Kusakari, Yoichiro, Kurihara, Satoshi

“…Myocardial intracellular calcium (Ca2+) transients (CaTs) regulate tension generation and relaxation. Isometric tension curves are often analyzed using…”
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Intracellular mechanism of the negative inotropic effect induced by alpha1-adrenoceptor stimulation in mouse myocardium by Hirano, Shuta, Kusakari, Yoichiro, O-Uchi, Jin, Morimoto, Satoshi, Kawai, Makoto, Hongo, Kenichi, Kurihara, Satoshi

“…Alpha(1)-adrenoceptor stimulation (alpha(1)ARS) shows a positive inotropic effect in most mammalian myocardium. In mouse myocardium, however, alpha(1)ARS…”
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The mechanism of contractile dysfunction in heart failure, focussing on SERCA2a function by Kusakari, Yoichiro, Hirano, Shuta, Hongo, Kenichi, Nakayama, Hiroyuki, Otsu, Kinya, Kurihara, Satoshi

“…Cytosolic Ca(2+) is a key regulator of excitation-contraction coupling in myocardium. Myocardial contractile dysfunction in heart failure is characterized by a…”
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Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca 2+ ATPase (SERCA2a) activity and impairs cardiac function in mice by Asahi, Michio, Otsu, Kinya, Nakayama, Hiroyuki, Hikoso, Shungo, Takeda, Toshihiro, Gramolini, Anthony O., Trivieri, Maria G., Oudit, Gavin Y., Morita, Takashi, Kusakari, Yoichiro, Hirano, Shuta, Hongo, Kenichi, Hirotani, Shinichi, Yamaguchi, Osamu, Peterson, Alan, Backx, Peter H., Kurihara, Satoshi, Hori, Masatsugu, MacLennan, David H.

“…Sarcolipin (SLN) inhibits the cardiac sarco(endo)plasmic reticulum Ca 2+ ATPase (SERCA2a) by direct binding and is superinhibitory if it binds through…”
Get full text