Search Results - "Hirano, Michiko"

Opening Closed Arms: Long-Distance Activation of SMC ATPase by Hinge-DNA Interactions by Hirano, Michiko, Hirano, Tatsuya

“…Structural maintenance of chromosomes (SMC) proteins form a V-shaped dimer in which a central hinge domain connects two coiled-coil arms, each having an ATP…”
Get full text

Reconstitution and subunit geometry of human condensin complexes by Onn, Itay, Aono, Nobuki, Hirano, Michiko, Hirano, Tatsuya

“…Vertebrate cells possess two different condensin complexes, known as condensin I and condensin II, that play a fundamental role in chromosome assembly and…”
Get full text

Differential Contributions of Condensin I and Condensin II to Mitotic Chromosome Architecture in Vertebrate Cells by Ono, Takao, Losada, Ana, Hirano, Michiko, Myers, Michael P., Neuwald, Andrew F., Hirano, Tatsuya

“…The canonical condensin complex (henceforth condensin I) plays an essential role in mitotic chromosome assembly and segregation from yeast to humans. We report…”
Get full text

Positive and negative regulation of SMC-DNA interactions by ATP and accessory proteins by Hirano, Michiko, Hirano, Tatsuya

“…Structural maintenance of chromosomes (SMC) proteins are central regulators of higher‐order chromosome dynamics from bacteria to humans. The Bacillus subtilis…”
Get full text

Identification of Xenopus SMC protein complexes required for sister chromatid cohesion by Losada, A, Hirano, M, Hirano, T

“…The structural maintenance of chromosomes (SMC) family is a growing family of chromosomal ATPases. The founding class of SMC protein complexes, condensins,…”
Get full text

Condensins, Chromosome Condensation Protein Complexes Containing XCAP-C, XCAP-E and a Xenopus Homolog of the Drosophila Barren Protein by Hirano, Tatsuya, Kobayashi, Ryuji, Hirano, Michiko

“…We report here purification and characterization of chro- mosome condensation protein complexes (termed condensins) containing XCAP-C and XCAP-E, two Xenopus…”
Get full text

Precise compositional analysis of liquid crystalline aromatic polyesters containing aromatic amide linkages by thermally assisted hydrolysis and methylation-gas chromatography by Ohtnai, Hajime, Sugimoto, Noriaki, Hirano, Michiko, Yokota, Toshiaki, Katoh, Kohichi

“…Multi-component liquid crystalline aromatic polyesters (LCPs) containing 4-aminophenol (PAP) units to form amide linkages were characterized by thermally…”
Get full text

Cpk Is a Novel Class of Drosophila PtdIns 3-Kinase Containing a C2 Domain by Molz, Lisa, Chen, Yen-Wen, Hirano, Michiko, Williams, Lewis T.

“…We report the identification of a novel class of phosphatidylinositol (PtdIns) 3-kinases whose members contain C-terminal C2 domains. We have isolated…”
Get full text

Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis by Losada, Ana, Hirano, Michiko, Hirano, Tatsuya

“…The establishment of metaphase chromosomes is an essential prerequisite of sister chromatid separation in anaphase. It involves the coordinated action of…”
Get full text

Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA by Hirano, Michiko, Hirano, Tatsuya

“…Structural maintenance of chromosomes (SMC) proteins play central roles in regulating higher order chromosome dynamics from bacteria to humans. As judged by…”
Get full text

Phosphorylation and Activation of 13S Condensin by Cdc2 In vitro by Kimura, Keiji, Hirano, Michiko, Kobayashi, Ryuji, Hirano, Tatsuya

“…135 condensin is a multisubunit protein complex essential for mitotic chromosome condensation in Xenopus egg extracts. Purified 135 condensin introduces…”
Get full text

ATP-dependent aggregation of single-stranded DNA by a bacterial SMC homodimer by Hirano, Michiko, Hirano, Tatsuya

“…SMC (structural maintenance of chromosomes) proteins are putative ATPases that are highly conserved among Bacteria, Archaea and Eucarya. Eukaryotic SMC…”
Get full text

Bimodal activation of SMC ATPase by intra- and inter-molecular interactions by Hirano, Michiko, Anderson, David E., Erickson, Harold P., Hirano, Tatsuya

“…Structural maintenance of chromosomes (SMC) proteins play fundamental roles in higher‐order chromosome dynamics from bacteria to humans. It has been proposed…”
Get full text

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity by KLIPPEL, A, ESCOBEDO, J. A, HIRANO, M, WILLIAMS, L. T

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Phosphorylation and Activation of 13 S Condensin by Cdc2 in Vitro by Kimura, Keiji, Hirano, Michiko, Kobayashi, Ryuji, Hirano, Tatsuya

“…13 S condensin is a multisubunit protein complex essential for mitotic chromosome condensation in Xenopus egg extracts. Purified 13 S condensin introduces…”
Get full text

The Interaction of Small Domains Between the Subunits of Phosphatidylinositol 3-Kinase Determines Enzyme Activity by Klippel, Anke, Escobedo, Jaime A., Hirano, Michiko, Williams, Lewis T.

“…Previous studies have suggested that the two subunits of phosphatidylinositol (PI) 3-kinase, p85 and p110, function as localizing and catalytic subunits,…”
Get full text

Mineralization ability of cultured human osteoblast-like periosteal cells does not decline with aging by Koshihara, Y, Hirano, M, Kawamura, M, Oda, H, Higaki, S

“…Studies of the mechanisms of osteoporosis have not yet determined whether these conditions result from increased osteoclast activity or decreased osteoblast…”
Get more information