Search Results - "Hiraki, L"
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Depressive and anxiety symptom prevalence in childhood-onset systemic lupus erythematosus: A systematic review
Published in Lupus (01-06-2019)“…Background Depressive and anxiety symptoms are common in children and youth and may impact outcomes for individuals with childhood-onset systemic lupus…”
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2
An adaptive and versatile method to quantitate and characterize collective cell migration behaviors on complex surfaces
Published in Frontiers in cell and developmental biology (26-01-2023)“…Collective cell migration is critical for proper embryonic development, wound healing, and cancer cell invasion. However, much of our knowledge of cell…”
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Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching
Published in Frontiers in bioengineering and biotechnology (16-06-2021)“…Fibrous extracellular matrix (ECM) proteins provide mechanical structure and adhesive scaffolding to resident cells within stromal tissues. Aligned ECM fibers…”
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4
Facile formation of giant elastin-like polypeptide vesicles as synthetic cells
Published in Chemical communications (Cambridge, England) (07-12-2021)“…We demonstrate the facile and robust generation of giant peptide vesicles by using an emulsion transfer method. These robust vesicles can sustain chemical and…”
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5
Measuring permanent damage in pediatric systemic lupus erythematosus
Published in Lupus (2007)“…The survival rates in pediatric systemic lupus erythematosus (pSLE) have improved greatly over recent decades. Increased life expectancy has meant that more…”
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6
Fiber density and matrix stiffness modulate distinct cell migration modes in a 3D stroma mimetic composite hydrogel
Published in Acta biomaterialia (01-06-2023)“…The peritumoral stroma is a complex 3D tissue that provides cells with myriad biophysical and biochemical cues. Histologic observations suggest that during…”
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7
Sulfide oxidation promotes hypoxic angiogenesis and neovascularization
Published in Nature chemical biology (01-10-2024)“…Angiogenic programming in the vascular endothelium is a tightly regulated process for maintaining tissue homeostasis and is activated in tissue injury and the…”
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Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone
Published in Acta biomaterialia (15-03-2020)“…Mechanical interactions between fibroblasts and their surrounding extracellular matrix (ECM) guide fundamental behaviors such as spreading, migration, and…”
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Direct comparison of angiogenesis in natural and synthetic biomaterials reveals that matrix porosity regulates endothelial cell invasion speed and sprout diameter
Published in Acta biomaterialia (01-11-2021)“…Vascularization of large, diffusion-hindered biomaterial implants requires an understanding of how extracellular matrix (ECM) properties regulate angiogenesis…”
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10
Rapid Magnetically Directed Assembly of Pre‐Patterned Capillary‐Scale Microvessels
Published in Advanced functional materials (02-10-2023)“…Capillary scale vascularization is critical to the survival of engineered 3D tissues and remains an outstanding challenge for the field of tissue engineering…”
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Physical and Soluble Cues Enhance Tendon Progenitor Cell Invasion into Injectable Synthetic Hydrogels
Published in Advanced functional materials (24-11-2022)“…Synthetic hydrogels represent an exciting avenue in the field of regenerative biomaterials given their injectability, orthogonally tunable mechanical…”
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12
Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel
Published in Journal of visualized experiments (13-10-2018)“…Extracellular matrix (ECM) provides important biophysical and biochemical cues to maintain tissue homeostasis. Current synthetic hydrogels offer robust…”
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The Role of Rho GTPases During Fibroblast Spreading, Migration, and Myofibroblast Differentiation in 3D Synthetic Fibrous Matrices
Published in Cellular and molecular bioengineering (01-10-2021)“…Introduction Connective tissue repair and mechanosensing are tightly entwined in vivo and occur within a complex three-dimensional (3D), fibrous extracellular…”
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14
Fetal Cardiac Targets Identify the Autoantibodies Associated with Congenital Heart Block
Published in ARTHRITIS & RHEUMATOLOGY (2022)Get full text
Conference Proceeding -
15
Gender differences in tobacco smoking: higher relative exposure to smoke than nicotine in women
Published in Journal of women's health & gender-based medicine (01-03-2002)“…Men and women are thought to regulate their smoking differently and to differ in their susceptibility to nicotine addiction. Various measures of smoke exposure…”
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Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000–2004
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-03-2013)“…Objective Systemic lupus erythematosus (SLE) and lupus nephritis (LN) disproportionately affect individuals who are members of racial/ethnic minority groups…”
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Pediatric lupus nephritis: impact of ethnicity on histological subtype and initial presentation
Published in Pediatric rheumatology online journal (15-09-2008)Get full text
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18
Integration of Composite Biomaterials and Microphysiologic Platforms for the Study of Cell Migration Phenotypes
Published 01-01-2024“…Cell migration is a complex process ubiquitously observed across both physiologic development and disease progression. The phenotype by which cells migrate…”
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Dissertation -
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Trends in the incidence, demographics, and outcomes of end‐stage renal disease due to lupus nephritis in the US from 1995 to 2006
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2011)“…Objective This study was undertaken to investigate whether recent advances in lupus nephritis treatment have led to changes in the incidence of end‐stage renal…”
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Journal Article -
20
Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel
Published in Journal of visualized experiments (13-10-2018)Get full text
Journal Article