Search Results - "Hirai, Miwa"

Helicobacter pylori infection and oxidative stress by Suzuki, Hidekazu, Hirai, Miwa

“…Helicobacter pylori (H. pylori) infection promotes the migration of polymorphonuclear leukocytes from the gastric mucosal microcirculation through chemokine…”
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Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera by Kabe, Yasuaki, Suematsu, Makoto, Sakamoto, Satoshi, Hirai, Miwa, Koike, Ikko, Hishiki, Takako, Matsuda, Atsushi, Hasegawa, Yuichi, Tsujita, Koji, Ono, Masayuki, Minegishi, Naoko, Hozawa, Atsushi, Murakami, Yoshinori, Kubo, Michiaki, Itonaga, Makoto, Handa, Hiroshi

“…Although circulating exosomes in blood play crucial roles in cancer development and progression, difficulties in quantifying exosomes hamper their application…”
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Helicobacter ailurogastricus in Patient with Multiple Refractory Gastric Ulcers, Japan by Sano, Masaya, Rimbara, Emiko, Suzuki, Masato, Matsui, Hidenori, Hirai, Miwa, Aoki, Sae, Kenri, Tsuyoshi, Shibayama, Keigo, Suzuki, Hidekazu

“…We report the isolation of Helicobacter ailurogastricus, a Helicobacter species that infects cats and dogs, from a person with multiple refractory gastric…”
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Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes by Furuhata, Ryogo, Kabe, Yasuaki, Kanai, Ayaka, Sugiura, Yuki, Tsugawa, Hitoshi, Sugiyama, Eiji, Hirai, Miwa, Yamamoto, Takehiro, Koike, Ikko, Yoshikawa, Noritada, Tanaka, Hirotoshi, Koseki, Masahiro, Nakae, Jun, Matsumoto, Morio, Nakamura, Masaya, Suematsu, Makoto

“…Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes…”
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Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 1 by Kabe, Yasuaki, Koike, Ikko, Yamamoto, Tatsuya, Hirai, Miwa, Kanai, Ayaka, Furuhata, Ryogo, Tsugawa, Hitoshi, Harada, Erisa, Sugase, Kenji, Hanadate, Kazue, Yoshikawa, Nobuji, Hayashi, Hiroaki, Noda, Masanori, Uchiyama, Susumu, Yamazaki, Hiroki, Tanaka, Hirotoshi, Kobayashi, Takuya, Handa, Hiroshi, Suematsu, Makoto

“…Progesterone receptor membrane component 1 (PGRMC1) is highly expressed in various cancer cells and contributes to tumor progression. We have previously shown…”
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O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer by Yokose, Takahiro, Kabe, Yasuaki, Matsuda, Atsushi, Kitago, Minoru, Matsuda, Sachiko, Hirai, Miwa, Nakagawa, Tomomi, Masugi, Yohei, Hishiki, Takako, Nakamura, Yuki, Shinoda, Masahiro, Yagi, Hiroshi, Abe, Yuta, Oshima, Go, Hori, Shutaro, Nakano, Yutaka, Honda, Kazufumi, Kashiro, Ayumi, Morizane, Chigusa, Nara, Satoshi, Kikuchi, Shojiro, Shibahara, Takahiko, Itonaga, Makoto, Ono, Masayuki, Minegishi, Naoko, Koshiba, Seizo, Yamamoto, Masayuki, Kuno, Atsushi, Handa, Hiroshi, Sakamoto, Michiie, Suematsu, Makoto, Kitagawa, Yuko

“…Pancreatic cancer (PC) is among the most lethal malignancies due to an often delayed and difficult initial diagnosis. Therefore, the development of a novel,…”
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Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites by Kabe, Yasuaki, Takemoto, Daisuke, Kanai, Ayaka, Hirai, Miwa, Ono, Yoshiko, Akazawa, Sota, Horikawa, Manabu, Kitagawa, Yoshinori, Handa, Hiroshi, Rogi, Tomohiro, Shibata, Hiroshi, Suematsu, Makoto

“…Sesamin [(7α,7′α,8α,8′α)-3,4:3′,4′-bis(methylenedioxy)-7,9′:7′,9-diepoxylignane] is a major lignan in sesame seeds. Sesamin is converted to the catechol…”
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Responsibility of lipid compositions for the amyloid ß assembly induced by ganglioside nanoclusters in mouse synaptosomal membranes by Matsubara, Teruhiko, Kojima, Takahiro, Fukuda, Ryoto, Iijma, Kazutoshi, Hirai, Miwa, Yamamoto, Naoki, Yanagisawa, Katsuhiko, Sato, Toshinori

“…The assembly of amyloid ß protein (Aß) on ganglioside-enriched microdomains in presynaptic neuronal membranes is involved in the onset of Alzheimer’s disease…”
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Tu1872 VERIFICATION OF PROGNOSTIC FACTORS RELATED WITH STEROID REFRACTORY ULCERATIVE COLITIS BY EXPLAINABLE ARTIFICIAL INTELLIGENCE: ANALYSIS OF A JAPANESE NATIONAL DATABASE FROM BEFORE THE SPREAD OF BIOLOGICS by Sano, Masaya, Kanatani, Yasuhiro, Hirai, Miwa, Nemoto, Shota, Suzuki, Hidekazu

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265 FUNCTIONAL ROLE OF GASTRIC-COMMENSAL BACTERIA IN THE DEVELOPMENT OF CD44V9-POSITIVE CANCER STEM-LIKE CELLS IN H. PYLORI-INFECTED GASTRIC MUCOSA by Tsugawa, Hitoshi, Sano, Masaya, Hirai, Miwa, Suzuki, Hidekazu

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Preparation of Cationic Comb-Type Copolymers Having High Density of PEG Graft Chains for Gene Carriers by Choi, Sung Won, Yamayoshi, Asako, Hirai, Miwa, Yamano, Takeshi, Takagi, Motoki, Sato, Ayumi, Kano, Arihiro, Shimamoto, Akira, Maruyama, Atsushi

“…A series of poly(L‐lysine)‐graft‐polyethylene glycol (PLL‐g‐PEG) was prepared by a reductive amination reaction of PLL with aldehyde modified PEG using NaBH3CN…”
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Heterogeneous Ganglioside-Enriched Nanoclusters with Different Densities in Membrane Rafts Detected by a Peptidyl Molecular Probe by Matsubara, Teruhiko, IIjima, Kazutoshi, Kojima, Takahiro, Hirai, Miwa, Miyamoto, Erika, Sato, Toshinori

“…The specific features of the lateral distribution of gangliosides play key roles in cell–cell communications and the onset of various diseases related to the…”
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Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery by Morimoto, Satoru, Takahashi, Shinichi, Ito, Daisuke, Daté, Yugaku, Okada, Kensuke, Kato, Chris, Nakamura, Shiho, Ozawa, Fumiko, Chyi, Chai Muh, Nishiyama, Ayumi, Suzuki, Naoki, Fujimori, Koki, Kondo, Tosho, Takao, Masaki, Hirai, Miwa, Kabe, Yasuaki, Suematsu, Makoto, Jinzaki, Masahiro, Aoki, Masashi, Fujiki, Yuto, Sato, Yasunori, Suzuki, Norihiro, Nakahara, Jin, Okano, Hideyuki

“…iPSC-based drug discovery led to a phase 1/2a trial of ropinirole in ALS. 20 participants with sporadic ALS received ropinirole or placebo for 24 weeks in the…”
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Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1 by Pati, Maria Laura, Groza, Diana, Riganti, Chiara, Kopecka, Joanna, Niso, Mauro, Berardi, Francesco, Hager, Sonja, Heffeter, Petra, Hirai, Miwa, Tsugawa, Hitoshi, Kabe, Yasuaki, Suematsu, Makoto, Abate, Carmen

“…[Display omitted] A controversial relationship between sigma-2 and progesterone receptor membrane component 1 (PGRMC1) proteins, both representing promising…”
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Synthesis of a New Ruthenium Complex of a Macrocyclic Ligand Containing 1,10-Phenanthroline, and Its Photo-Mediated Covalent Binding to DNA by Hirai, Miwa, Shinozuka, Kazuo, Ogawa, Shojiro, Sawai, Hiroaki

“…A ruthenium complex of a macrocyclic compound, consisting of two 1,10-phenanthroline molecules bridged by sulfur, was synthesized by template-directed…”
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Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life by Sato, Ayumi, Choi, Sung Won, Hirai, Miwa, Yamayoshi, Asako, Moriyama, Rui, Yamano, Takeshi, Takagi, Motoki, Kano, Arihiro, Shimamoto, Akira, Maruyama, Atsushi

“…Delivery systems of small interfering RNA (siRNA) are the key to siRNA therapeutic application. In this study, we prepared and evaluated a series of cationic…”
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Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites by Kabe, Yasuaki, Takemoto, Daisuke, Kanai, Ayaka, Hirai, Miwa, Ono, Yoshiko, Akazawa, Sota, Horikawa, Manabu, Kitagawa, Yoshinori, Handa, Hiroshi, Rogi, Tomohiro, Shibata, Hiroshi, Suematsu, Makoto

“…Sesamin [(7α,7'α,8α,8'α)-3,4:3',4'-bis(methylenedioxy)-7,9':7',9-diepoxylignane] is a major lignan in sesame seeds. Sesamin is converted to the catechol…”
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N-bonded enolatorhenium(I) complexes having dimethylphenylphosphine ligands as active key intermediates in catalytic Knoevenagel and Michael reactions by Hirano, Masafumi, Hirai, Miwa, Ito, Yuji, Tsurumaki, Tsutomu, Baba, Atsushi, Fukuoka, Atsushi, Komiya, Sanshiro

“…Enolatorhenium(I) complexes cis-Re(NCCRCO 2R′)(NCCHRCO 2R′)(PMe 2Ph) 4 (R=H, R′=Me ( 2a); R=H, R′=Et ( 2b); R=H, R′= n-Bu ( 2c); R=Me, R′=Et ( 2d)) are…”
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