Search Results - "Hippocampus"

Hippocampal sharp wave-ripple: A cognitive biomarker for episodic memory and planning by Buzsaki, György

“…ABSTRACT Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the mammalian brain. Their excitatory output affects a wide area of…”
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Space, time, and episodic memory: The hippocampus is all over the cognitive map by Ekstrom, Arne D., Ranganath, Charan

“…In recent years, the field has reached an impasse between models suggesting that the hippocampus is fundamentally involved in spatial processing and models…”
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Transcending time in the brain: How event memories are constructed from experience by Clewett, David, DuBrow, Sarah, Davachi, Lila

“…Our daily lives unfold continuously, yet when we reflect on the past, we remember those experiences as distinct and cohesive events. To understand this…”
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Neurons and networks in the entorhinal cortex: A reappraisal of the lateral and medial entorhinal subdivisions mediating parallel cortical pathways by Nilssen, Eirik S., Doan, Thanh P., Nigro, Maximiliano J., Ohara, Shinya, Witter, Menno P.

“…In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the entorhinal cortex with a focus on the concept of parallel…”
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The social hippocampus by Montagrin, Alison, Saiote, Catarina, Schiller, Daniela

“…The concept of cognitive map has been proposed as a way to organize our experiences and guide behavior across all domains of cognition. The hippocampus has…”
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The content of hippocampal “replay” by Pfeiffer, Brad E.

“…One of the most striking features of the hippocampal network is its ability to self‐generate neuronal sequences representing temporally compressed, spatially…”
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Episodic memory: Neuronal codes for what, where, and when by Sugar, Jørgen, Moser, May‐Britt

“…Episodic memory is defined as the ability to recall events in a spatiotemporal context. Formation of such memories is critically dependent on the hippocampal…”
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Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice by Naninck, Eva F.G., Hoeijmakers, Lianne, Kakava-Georgiadou, Nefeli, Meesters, Astrid, Lazic, Stanley E., Lucassen, Paul J., Korosi, Aniko

“…ABSTRACT Early life stress (ES) increases vulnerability to psychopathology and impairs cognition in adulthood. These ES‐induced deficits are associated with…”
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Hippocampal spatial view cells for memory and navigation, and their underlying connectivity in humans by Rolls, Edmund T.

“…Hippocampal and parahippocampal gyrus spatial view neurons in primates respond to the spatial location being looked at. The representation is allocentric, in…”
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Statistical learning of temporal community structure in the hippocampus by Schapiro, Anna C., Turk-Browne, Nicholas B., Norman, Kenneth A., Botvinick, Matthew M.

“…ABSTRACT The hippocampus is involved in the learning and representation of temporal statistics, but little is understood about the kinds of statistics it can…”
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Exercise interventions preserve hippocampal volume: A meta‐analysis by Wilckens, Kristine A., Stillman, Chelsea M., Waiwood, Aashna M., Kang, Chaeryon, Leckie, Regina L., Peven, Jamie C., Foust, Jill E., Fraundorf, Scott H., Erickson, Kirk I.

“…Hippocampal volume is a marker of brain health and is reduced with aging and neurological disease. Exercise may be effective at increasing and preserving…”
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Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis by Garthe, Alexander, Roeder, Ingo, Kempermann, Gerd

“…ABSTRACT We here show that living in a stimulus‐rich environment (ENR) improves water maze learning with respect to specific key indicators that in previous…”
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Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults by Yassa, Michael A., Lacy, Joyce W., Stark, Shauna M., Albert, Marilyn S., Gallagher, Michela, Stark, Craig E.L.

“…There is widespread evidence that memory deteriorates with aging, however the exact mechanisms that underlie these changes are not well understood. Given the…”
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Quantitative assessment of CA1 local circuits: Knowledge base for interneuron-pyramidal cell connectivity by Bezaire, Marianne J., Soltesz, Ivan

“…ABSTRACT In this work, through a detailed literature review, data‐mining, and extensive calculations, we provide a current, quantitative estimate of the…”
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Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss by Ager, Rahasson R., Davis, Joy L., Agazaryan, Andy, Benavente, Francisca, Poon, Wayne W., LaFerla, Frank M., Blurton-Jones, Mathew

“…ABSTRACT Alzheimer's disease (AD) is the most prevalent age‐related neurodegenerative disorder, affecting over 35 million people worldwide. Pathologically, AD…”
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Meta‐analytic and functional connectivity evidence from functional magnetic resonance imaging for an anterior to posterior gradient of function along the hippocampal axis by Grady, Cheryl L.

“…There is considerable evidence from non‐human animal studies that the anterior and posterior regions of the hippocampus have different anatomical connections…”
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Human hippocampal theta oscillations and the formation of episodic memories by Lega, Bradley C., Jacobs, Joshua, Kahana, Michael

“…The importance of the hippocampal theta oscillation (4–8 Hz) to memory formation has been well‐established through studies in animals, prompting researchers to…”
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Effects of sucrose and high fructose corn syrup consumption on spatial memory function and hippocampal neuroinflammation in adolescent rats by Hsu, Ted M., Konanur, Vaibhav R., Taing, Lilly, Usui, Ryan, Kayser, Brandon D., Goran, Michael I., Kanoski, Scott E.

“…ABSTRACT Excessive consumption of added sugars negatively impacts metabolic systems; however, effects on cognitive function are poorly understood. Also unknown…”
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A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals? by Wisse, Laura E.M., Daugherty, Ana M., Olsen, Rosanna K., Berron, David, Carr, Valerie A., Stark, Craig E.L., Amaral, Robert S.C., Amunts, Katrin, Augustinack, Jean C., Bender, Andrew R., Bernstein, Jeffrey D., Boccardi, Marina, Bocchetta, Martina, Burggren, Alison, Chakravarty, M. Mallar, Chupin, Marie, Ekstrom, Arne, de Flores, Robin, Insausti, Ricardo, Kanel, Prabesh, Kedo, Olga, Kennedy, Kristen M., Kerchner, Geoffrey A., LaRocque, Karen F., Liu, Xiuwen, Maass, Anne, Malykhin, Nicolai, Mueller, Susanne G., Ofen, Noa, Palombo, Daniela J., Parekh, Mansi B., Pluta, John B., Pruessner, Jens C., Raz, Naftali, Rodrigue, Karen M., Schoemaker, Dorothee, Shafer, Andrea T., Steve, Trevor A., Suthana, Nanthia, Wang, Lei, Winterburn, Julie L., Yassa, Michael A., Yushkevich, Paul A., la Joie, Renaud

“…ABSTRACT The advent of high‐resolution magnetic resonance imaging (MRI) has enabled in vivo research in a variety of populations and diseases on the structure…”
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Aerobic fitness is associated with hippocampal volume in elderly humans by Erickson, Kirk I., Prakash, Ruchika S., Voss, Michelle W., Chaddock, Laura, Hu, Liang, Morris, Katherine S., White, Siobhan M., Wójcicki, Thomas R., McAuley, Edward, Kramer, Arthur F.

“…Deterioration of the hippocampus occurs in elderly individuals with and without dementia, yet individual variation exists in the degree and rate of hippocampal…”
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