Search Results - "Hipp, S"

Heavy metal‐associated isoprenylated plant protein (HIPP): characterization of a family of proteins exclusive to plants by Abreu‐Neto, João Braga, Turchetto‐Zolet, Andreia C., Oliveira, Luiz Felipe Valter, Bodanese Zanettini, Maria Helena, Margis‐Pinheiro, Marcia

“…Metallochaperones are key proteins for the safe transport of metallic ions inside the cell. HIPPs (heavy metal…”
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Cancer statistics for adolescents and young adults, 2020 by Miller, Kimberly D., Fidler‐Benaoudia, Miranda, Keegan, Theresa H., Hipp, Heather S., Jemal, Ahmedin, Siegel, Rebecca L.

“…Cancer statistics for adolescents and young adults (AYAs) (aged 15‐39 years) are often presented in aggregate, masking important heterogeneity. The authors…”
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Molecular chaperone functions in protein folding and proteostasis by Kim, Yujin E, Hipp, Mark S, Bracher, Andreas, Hayer-Hartl, Manajit, Hartl, F Ulrich

“…The biological functions of proteins are governed by their three-dimensional fold. Protein folding, maintenance of proteome integrity, and protein homeostasis…”
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Proteostasis impairment in protein-misfolding and -aggregation diseases by Hipp, Mark S, Park, Sae-Hun, Hartl, F. Ulrich

“…Highlights • Cells possess a complex proteostasis network (PN) to ensure protein homeostasis. • Aggregates permanently engage molecular chaperones and other PN…”
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PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone by Park, Sae-Hun, Kukushkin, Yury, Gupta, Rajat, Chen, Taotao, Konagai, Ayano, Hipp, Mark S., Hayer-Hartl, Manajit, Hartl, F. Ulrich

“…Dysfunction of protein quality control contributes to the cellular pathology of polyglutamine (polyQ) expansion diseases and other neurodegenerative disorders…”
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The nucleolus functions as a phase-separated protein quality control compartment by Frottin, F, Schueder, F, Tiwary, S, Gupta, R, Körner, R, Schlichthaerle, T, Cox, J, Jungmann, R, Hartl, F U, Hipp, M S

“…The nuclear proteome is rich in stress-sensitive proteins, which suggests that effective protein quality control mechanisms are in place to ensure…”
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In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment by Guo, Qiang, Lehmer, Carina, Martínez-Sánchez, Antonio, Rudack, Till, Beck, Florian, Hartmann, Hannelore, Pérez-Berlanga, Manuela, Frottin, Frédéric, Hipp, Mark S., Hartl, F. Ulrich, Edbauer, Dieter, Baumeister, Wolfgang, Fernández-Busnadiego, Rubén

“…Protein aggregation and dysfunction of the ubiquitin-proteasome system are hallmarks of many neurodegenerative diseases. Here, we address the elusive link…”
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The endoplasmic reticulum: A hub of protein quality control in health and disease by Vincenz-Donnelly, Lisa, Hipp, Mark S.

“…One third of the eukaryotic proteome is synthesized at the endoplasmic reticulum (ER), whose unique properties provide a folding environment substantially…”
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In Situ Architecture and Cellular Interactions of PolyQ Inclusions by Bäuerlein, Felix J.B., Saha, Itika, Mishra, Archana, Kalemanov, Maria, Martínez-Sánchez, Antonio, Klein, Rüdiger, Dudanova, Irina, Hipp, Mark S., Hartl, F. Ulrich, Baumeister, Wolfgang, Fernández-Busnadiego, Rubén

“…Expression of many disease-related aggregation-prone proteins results in cytotoxicity and the formation of large intracellular inclusion bodies. To gain…”
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Identification of novel rice (Oryza sativa) HPP and HIPP genes tolerant to heavy metal toxicity by khan, Irfan ullah, Rono, Justice Kipkoir, Zhang, Bai Qing, Liu, Xue Song, Wang, Meng Qi, Wang, Lei Lei, Wu, Xue Chun, Chen, Xi, Cao, Hong Wei, Yang, Zhi Min

“…HPP (heavy metal associated plant protein) and HIPP (heavy metal associated isoprenylated plant protein…”
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Characterization of the Heavy-Metal-Associated Isoprenylated Plant Protein ( HIPP ) Gene Family from Triticeae Species by Zhang, Heng, Zhang, Xu, Liu, Jia, Niu, Ying, Chen, Yiming, Hao, Yongli, Zhao, Jia, Sun, Li, Wang, Haiyan, Xiao, Jin, Wang, Xiue

“…Heavy-metal-associated (HMA) isoprenylated plant proteins (HIPPs) only exist in vascular plants…”
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A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo by Hipp, S, Tai, Y-T, Blanset, D, Deegen, P, Wahl, J, Thomas, O, Rattel, B, Adam, P J, Anderson, K C, Friedrich, M

“…B-cell maturation antigen (BCMA) is a highly plasma cell-selective protein that is expressed on malignant plasma cells of multiple myeloma (MM) patients and…”
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In situ architecture of neuronal α-Synuclein inclusions by Trinkaus, Victoria A., Riera-Tur, Irene, Martínez-Sánchez, Antonio, Bäuerlein, Felix J. B., Guo, Qiang, Arzberger, Thomas, Baumeister, Wolfgang, Dudanova, Irina, Hipp, Mark S., Hartl, F. Ulrich, Fernández-Busnadiego, Rubén

“…The molecular architecture of α-Synuclein (α-Syn) inclusions, pathognomonic of various neurodegenerative disorders, remains unclear. α-Syn inclusions were long…”
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Nutritional safety and suitability of a specific protein hydrolysate derived from whey protein concentrate and used in an infant and follow‐on formula manufactured from hydrolysed protein by HIPP‐Werk Georg Hipp OHG (dossier submitted by meyer.science GmbH) by Bohn, Torsten, Castenmiller, Jacqueline, de Henauw, Stefaan, Hirsch‐Ernst, Karen‐Ildico, Katrine Knutsen, Helle, Maciuk, Alexandre, Mangelsdorf, Inge, McArdle, Harry J, Naska, Androniki, Pelaez, Carmen, Pentieva, Kristina, Siani, Alfonso, Thies, Frank, Tsabouri, Sophia, Vinceti, Marco, Bresson, Jean‐Louis, Castle, Laurence, Fewtrell, Mary, Przyrembel, Hildegard, Dumas, Céline, Titz, Ariane, Turck, Dominique

“… It is derived from whey protein concentrate and used in infant and follow‐on formula by HIPP‐Werk Georg Hipp OHG. The dossier that was submitted to the European Commission aimed at requesting an amendment of Regulation…”
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Genome-wide identification of HIPP and mechanism of SlHIPP4/7/9/21/26/32 mediated phytohormones response to Cd, osmotic, and salt stresses in tomato by Xu, Junrong, Cui, Jing, He, Qiuyu, Liu, Yunzhi, Lu, Xuefang, Qi, Jin, Xiong, Jingli, Yu, Wenjin, Li, Changxia

“…Heavy-metal-associated isoprenylated plant proteins (HIPPs) contributed to abiotic tolerance in vascular plants…”
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Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons by Riemenschneider, Henrick, Guo, Qiang, Bader, Jakob, Frottin, Frédéric, Farny, Daniel, Kleinberger, Gernot, Haass, Christian, Mann, Matthias, Hartl, F. Ulrich, Baumeister, Wolfgang, Hipp, Mark S, Meissner, Felix, Fernández‐Busnadiego, Rubén, Edbauer, Dieter

“…Aggregation of the multifunctional RNA‐binding protein TDP‐43 defines large subgroups of amyotrophic lateral sclerosis and frontotemporal dementia and…”
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The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model by Yuste-Checa, Patricia, Trinkaus, Victoria A., Riera-Tur, Irene, Imamoglu, Rahmi, Schaller, Theresa F., Wang, Huping, Dudanova, Irina, Hipp, Mark S., Bracher, Andreas, Hartl, F. Ulrich

“…Spreading of aggregate pathology across brain regions acts as a driver of disease progression in Tau-related neurodegeneration, including Alzheimer’s disease…”
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Extremities of body mass index and their association with pregnancy outcomes in women undergoing in vitro fertilization in the United States by Kawwass, Jennifer F., M.D, Kulkarni, Aniket K., M.B.B.S., M.P.H, Hipp, Heather S., M.D, Crawford, Sara, Ph.D, Kissin, Dmitry M., M.D., M.P.H, Jamieson, Denise J., M.D., M.P.H

“…Objective To investigate the associations among underweight body mass index (BMI), pregnancy, and obstetric outcomes among women using assisted reproductive…”
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Minocycline Ameliorates Chronic Unpredictable Mild Stress-Induced Neuroinflammation and Abnormal mPFC-HIPP Oscillations in Mice by Tabassum, Sidra, Misrani, Afzal, Huo, Qingwei, Ahmed, Adeel, Long, Cheng, Yang, Li

“…) alters mitochondrial function and subsequent medial prefrontal cortex-hippocampus (mPFC-HIPP) connectivity remains obscure…”
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Arabidopsis HIPP proteins regulate endoplasmic reticulum-associated degradation of CKX proteins and cytokinin responses by Guo, Tianqi, Weber, Henriette, Niemann, Michael C E, Theisl, Lisa, Leonte, Georgeta, Novák, Ondřej, Werner, Tomáš

“… Here, we show that heavy metal-associated isoprenylated plant proteins (HIPPs) interact specifically with CKX proteins synthesized in the ER and processed by ERAD…”
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