Search Results - "Hiorns, Lynne R"

Genomic Imbalances Associated with Acquired Resistance to Platinum Analogues by Leyland-Jones, Brian, Kelland, Lloyd R., Harrap, Kenneth R., Hiorns, Lynne R.

“…During the past several years, a panel of human tumor cell lines (predominantly ovarian) with acquired resistance to cisplatin, the orally bioavailable…”
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Abnormalities of Chromosomes 8, 11, 14, and X in T-Prolymphocytic Leukemia Studied by Fluorescence In Situ Hybridization by Maljaei, Seyed Hoda, Brito-Babapulle, Vasantha, Hiorns, Lynne R, Catovsky, Daniel

“…Twenty-one patients with T-prolymphocytic leukemia (T-PLL) were studied by FISH to characterize abnormalities of chromosomes 8, 11, 14, and X. A higher…”
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Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia by HIORNS, LYNNE R., SWANSBURY, G. JOHN, MEHTA, JAYESH, MIN, TOON, DAINTON, MELISSA G., TRELEAVEN, JENNIE, POWLES, RAYMOND L., CATOVSKY, DANIEL

“…Acute promyelocytic leukaemia (APL) has been associated with a favourable prognosis in many studies of acute myeloid leukaemia. A series of 54 patients treated…”
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Genomic imbalances associated with acquired resistence to platinum analogues by Leyland-Jones, Brian, Kelland, Lloyd R, Harrap, Kenneth R, Hiorns, Lynne R

“…During the past several years, a panel of human tumor cell lines (predominantly ovarian) with acquired resistance to cisplatin, the orally bioavailable…”
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Gene Expression Profiling of 2-(4-Aminophenyl)benzothiazole-resistant MCF-7 Cells Using cDNA Microarrays by QINGNAN YU, LYNNE R. HIORNS, TRACEY D. BRADSHAW, MALCOLM F. G. STEVENS, BRIAN LEYLAND-JONES

“…Background: CJM126, 2-(4-aminophenyl) benzothiazole, is a potent inhibitor of human-derived breast carcinoma cell lines. Previous studies have shown that…”
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Interleukin-4 Enhances the Survival of Severe Combined Immunodeficient Mice Engrafted With Human B-Cell Precursor Leukemia by Mitchell, Paul L.R., Clutterbuck, Robyn D., Powles, Ray L., De Lord, Corinne, Morilla, Ricardo, Hiorns, Lynne R., Titley, Jennifer, Catovsky, Daniel, Millar, John L.

“…Human interleukin-4 (hulL-4) has been shown to inhibit the growth in vitro of cells from patients with acute lymphoblastic leukemia (ALL). With the aim of…”
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Nucleotide Sequence of cDNA Encoding Human α2-macroglobulin and Assignment of the Chromosomal Locus by Kan, Chen-Chen, Solomon, Ellen, Belt, K. Tertia, Chain, Aileen C., Hiorns, Lynne R., Fey, Georg

“…Six α2-macroglobulin (α2M) cDNA clones were isolated from a human liver cDNA library by using synthetic oligonucleotides as hybridization probes. One of these,…”
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Bilineal Acute Leukemia of B and T Lineage with a Novel Translocation t(9;17)(p11;q11) by Zomas, Athanasios P., Swansbury, G. John, Matutes, Estella, Pinkerton, Ross, Morns, Lynne R., Min, Toon, Farahat, Nahla, Catovsky, Daniel

“…We describe a case of bilineal leukemia in a 5-year old boy with a rare immunophenotype and the novel translocation t(9;17)(p11;q11) as the sole chromosomal…”
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Co-incident N and K ras gene mutations in a case of AML, restricted to differing cell lineages by Hiorns, L R, Cotter, F E, Young, B D

“…Peripheral blood from a patient with acute myeloid leukaemia (AML) of M5 FAB classification, was shown to have mutations to both the N and K ras genes…”
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Ki-ras oncogene mutations in non-HPV-associated anal carcinoma by Hiorns, L R, Scholefield, J H, Palmer, J G, Shepherd, N A, Kerr, I B

“…Human papillomavirus 16 (HPV 16) DNA is found in a high proportion of anal squamous cell carcinomas in whose genesis it is thought to play an important role…”
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Genetic Analysis of the 15;17 Chromosome Translocation Associated with Acute Promyelocytic Leukemia by Sheer, Denise, Hiorns, Lynne R., Stanley, Karina F., Goodfellow, Peter N., Swallow, Dallas M., Povey, Susan, Heisterkamp, Nora, Groffen, John, Stephenson, John R., Solomon, Ellen

“…Somatic cell hybrids have been constructed between a thymidine kinase-deficient mouse cell line and blood leukocytes from a patient with acute promyelocytic…”
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An eight-way variant t(15;17) in acute promyelocytic leukemia elucidated using fluorescence in situ hybridization by Hiorns, Lynne R., John Swansbury, G., Catovsky, Daniel

“…A complex eight-way translocation was identified, with the aid of fluorescence in situ hybridization (FISH), in a patient diagnosed as having acute…”
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Partial trisomy of chromosome 4 resulting from a novel t(4;7) translocation in a case of AML M2 with eosinophilia by Hiorns, Lynne R., John Swansbury, G., Zomas, Athanassios, Catovsky, Daniel

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