Search Results - "Hinske, Ludwig Christian"

MiRNAs: dynamic regulators of immune cell functions in inflammation and cancer by Hirschberger, Simon, Hinske, Ludwig Christian, Kreth, Simone

“…MicroRNAs (miRNAs), small noncoding RNA molecules, have emerged as important regulators of almost all cellular processes. By binding to specific sequence…”
Get full text

Federated Secure Computing by Ballhausen, Hendrik, Hinske, Ludwig Christian

“…Privacy-preserving computation (PPC) enables encrypted computation of private data. While advantageous in theory, the complex technology has steep barriers to…”
Get full text

Designing an ML Auditing Criteria Catalog as Starting Point for the Development of a Framework by Schwarz, Markus, Hinske, Ludwig Christian, Mansmann, Ulrich, Albashiti, Fady

“…Although AI algorithms and applications become more and popular in the healthcare sector, only few institutions have an operational AI strategy. Identifying…”
Get full text

A Functional Network Driven by MicroRNA-125a Regulates Monocyte Trafficking in Acute Inflammation by Tomasi, Stephanie, Li, Lei, Hinske, Ludwig Christian, Tomasi, Roland, Amini, Martina, Strauß, Gabriele, Müller, Martin Bernhard, Hirschberger, Simon, Peterss, Sven, Effinger, David, Pogoda, Kristin, Kreth, Simone, Hübner, Max

“…During the onset of acute inflammation, rapid trafficking of leukocytes is essential to mount appropriate immune responses towards an inflammatory insult…”
Get full text

Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR by Hinske, Ludwig Christian, Galante, Pedro A F, Limbeck, Elisabeth, Möhnle, Patrick, Parmigiani, Raphael B, Ohno-Machado, Lucila, Camargo, Anamaria A, Kreth, Simone

“…About half of the known miRNA genes are located within protein-coding host genes, and are thus subject to co-transcription. Accumulating data indicate that…”
Get full text

Predicting Hypoxia Using Machine Learning: Systematic Review by Pigat, Lena, Geisler, Benjamin P, Sheikhalishahi, Seyedmostafa, Sander, Julia, Kaspar, Mathias, Schmutz, Maximilian, Rohr, Sven Olaf, Wild, Carl Mathis, Goss, Sebastian, Zaghdoudi, Sarra, Hinske, Ludwig Christian

“…Hypoxia is an important risk factor and indicator for the declining health of inpatients. Predicting future hypoxic events using machine learning is a…”
Get full text

Predicting Successful Weaning from Mechanical Ventilation by Reduction in Positive End-expiratory Pressure Level Using Machine Learning by Sheikhalishahi, Seyedmostafa, Kaspar, Mathias, Zaghdoudi, Sarra, Sander, Julia, Simon, Philipp, Geisler, Benjamin P, Lange, Dorothea, Hinske, Ludwig Christian

“…Weaning patients from mechanical ventilation (MV) is a critical and resource intensive process in the Intensive Care Unit (ICU) that impacts patient outcomes…”
Get full text

MicroRNAs as Clinical Biomarkers and Therapeutic Tools in Perioperative Medicine by Kreth, Simone, Hübner, Max, Hinske, Ludwig Christian

“…Over the past decade, evolutionarily conserved, noncoding small RNAs—so-called microRNAs (miRNAs)—have emerged as important regulators of virtually all…”
Get full text

Soluble intercellular adhesion molecule-1: a potential biomarker for pain intensity in chronic pain patients by Luchting, Benjamin, Hinske, Ludwig Christian Giuseppe, Rachinger-Adam, Banafscheh, Celi, Leo Anthony, Kreth, Simone, Azad, Shahnaz Christina

“…Pain therapy is strongly guided by patients' self-reporting. However, when self-reporting is not an option, pain assessment becomes a challenge and may lead to…”
Get full text

Prediction of blood transfusion in intensive care patients after surgery by Sheikhalishahi, Seyedmostafa, Kaspar, Mathias, Goss, Sebastian, Schwinn, Johanna, Hinske, Ludwig Christian

Get full text

Mechanical Power Density Predicts Prolonged Ventilation Following Double Lung Transplantation by Ghiani, Alessandro, Kneidinger, Nikolaus, Neurohr, Claus, Frank, Sandra, Hinske, Ludwig Christian, Schneider, Christian, Michel, Sebastian, Irlbeck, Michael

“…Prolonged mechanical ventilation (PMV) after lung transplantation poses several risks, including higher tracheostomy rates and increased in-hospital mortality…”
Get full text

Electronic data capture in resource-limited settings using the lightweight clinical data acquisition and recording system by Vielhauer, Jakob, Mahajan, Ujjwal Mukund, Adorjan, Kristina, Benesch, Christopher, Oehrle, Bettina, Beyer, Georg, Sirtl, Simon, Johlke, Anna-Lena, Allgeier, Julian, Pernpruner, Anna, Erber, Johanna, Shamsrizi, Parichehr, Schulz, Christian, Albashiti, Fady, Hinske, Ludwig Christian, Mayerle, Julia, Stubbe, Hans Christian

“…Our prototype system designed for clinical data acquisition and recording of studies is a novel electronic data capture (EDC) software for simple and…”
Get full text

From RNA sequencing measurements to the final results: A practical guide to navigating the choices and uncertainties of gene set analysis by Wünsch, Milena, Sauer, Christina, Callahan, Patrick, Hinske, Ludwig Christian, Boulesteix, Anne‐Laure

“…Gene set analysis (GSA), a popular approach for analyzing high‐throughput gene expression data, aims to identify sets of related genes that show significantly…”
Get full text

Data suggested hospitalization as critical indicator of the severity of the COVID-19 pandemic, even at its early stages by Fuderer, Stefanie, Kuttler, Christina, Hoelscher, Michael, Hinske, Ludwig Christian, Castelletti, Noemi

“…COVID-19 has been spreading widely since January 2020, prompting the implementation of non-pharmaceutical interventions and vaccinations to prevent…”
Get full text

A potential role for intragenic miRNAs on their hosts' interactome by Hinske, Ludwig Christian G, Galante, Pedro A F, Kuo, Winston P, Ohno-Machado, Lucila

“…miRNAs are small, non-coding RNA molecules that mainly act as negative regulators of target gene messages. Due to their regulatory functions, they have lately…”
Get full text

Integrative modelling of reported case numbers and seroprevalence reveals time-dependent test efficiency and infectious contacts by Contento, Lorenzo, Castelletti, Noemi, Raimúndez, Elba, Le Gleut, Ronan, Schälte, Yannik, Stapor, Paul, Hinske, Ludwig Christian, Hoelscher, Michael, Wieser, Andreas, Radon, Katja, Fuchs, Christiane, Hasenauer, Jan

“…Mathematical models have been widely used during the ongoing SARS-CoV-2 pandemic for data interpretation, forecasting, and policy making. However, most models…”
Get full text

Early Use of Methylene Blue in Vasoplegic Syndrome: A 10-Year Propensity Score-Matched Cohort Study by Kofler, Othmar, Simbeck, Maximilian, Tomasi, Roland, Hinske, Ludwig Christian, Klotz, Laura Valentina, Uhle, Florian, Born, Frank, Pichlmaier, Maximilian, Hagl, Christian, Weigand, Markus Alexander, Zwißler, Bernhard, von Dossow, Vera

“…Vasoplegic syndrome is associated with increased morbidity and mortality in patients undergoing cardiac surgery. This retrospective, single-center study aimed…”
Get full text

Towards interoperability in infection control: a standard data model for microbiology by Rinaldi, Eugenia, Drenkhahn, Cora, Gebel, Benjamin, Saleh, Kutaiba, Tönnies, Hauke, von Loewenich, Friederike D., Thoma, Norbert, Baier, Claas, Boeker, Martin, Hinske, Ludwig Christian, Diaz, Luis Alberto Peña, Behnke, Michael, Ingenerf, Josef, Thun, Sylvia

“…The COVID-19 pandemic has made it clear: sharing and exchanging data among research institutions is crucial in order to efficiently respond to global health…”
Get full text

Author Correction: Towards interoperability in infection control: a standard data model for microbiology by Rinaldi, Eugenia, Drenkhahn, Cora, Gebel, Benjamin, Saleh, Kutaiba, Tönnies, Hauke, von Loewenich, Friederike D., Thoma, Norbert, Baier, Claas, Boeker, Martin, Hinske, Ludwig Christian, Diaz, Luis Alberto Peña, Behnke, Michael, Ingenerf, Josef, Thun, Sylvia

Get full text

Predicting the Necessity for Extracorporeal Circulation During Lung Transplantation: A Feasibility Study by Hinske, Ludwig Christian, MD, Hoechter, Dominik Johannes, MD, Schröeer, Eva, Kneidinger, Nikolaus, MD, PhD, Schramm, René, MD, PhD, Preissler, Gerhard, MD, Tomasi, Roland, MD, Sisic, Alma, Frey, Lorenz, MD, von Dossow, Vera, MD, Scheiermann, Patrick, MD, PhD

“…Objective The factors leading to the implementation of unplanned extracorporeal circulation during lung transplantation are poorly defined. Consequently, the…”
Get full text