Search Results - "Hinrichs, John W J"

Prognostic Value of CTNNB1 Gene Mutation in Primary Sporadic Aggressive Fibromatosis by van Broekhoven, Danique L. M., Verhoef, Cornelis, Grünhagen, Dirk J., van Gorp, Joost M. H. H., den Bakker, Michael A., Hinrichs, John W. J., de Voijs, Carmen M. A., van Dalen, Thijs

“…Background Aggressive fibromatosis (AF) comprises tumors with a varying biological behavior. Genetic tumor characteristics may be predictive of recurrence;…”
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One-fits-all pretreatment protocol facilitating Fluorescence In Situ Hybridization on formalin-fixed paraffin-embedded, fresh frozen and cytological slides by Richardson, Shivanand O, Huibers, Manon M H, de Weger, Roel A, de Leng, Wendy W J, Hinrichs, John W J, Meijers, Ruud W J, Willems, Stefan M, Peeters, Ton L M G

“…The Fluorescence In Situ Hybridization (FISH) technique is a very useful tool for diagnostic and prognostic purposes in molecular pathology. However, clinical…”
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Added value of HER-2 amplification testing by multiplex ligation-dependent probe amplification in invasive breast cancer by Kuijpers, Chantal C H J, Moelans, Cathy B, van Slooten, Henk-Jan, Horstman, Anja, Hinrichs, John W J, Al-Janabi, Shaimaa, van Diest, Paul J, Jiwa, Mehdi

“…HER-2 is a prognostic and predictive marker, but as yet no technique is perfectly able to identify patients likely to benefit from HER-2 targeted therapies. We…”
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Semi-quantitative CYP2D6 gene doses in relation to metabolic ratios of psychotropics by Hinrichs, John W. J., Loovers, Harriët M., Scholten, Bart, van der Weide, Jan

“…Purpose Genetic polymorphisms in cytochrome P450 (CYP) enzyme CYP2D6 have a substantial effect on the success of pharmacotherapy. Different models, including a…”
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Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity by van den Broek, Daan, Hiltermann, T Jeroen N, Biesma, Bonne, Dinjens, Winand N M, 't Hart, Nils A, Hinrichs, John W J, Leers, Mathie P G, Monkhorst, Kim, van Oosterhout, Matthijs, Scharnhorst, Volkher, Schuuring, Ed, Speel, Ernst-Jan M, van den Heuvel, Michel M, van Schaik, Ron H N, von der Thüsen, Jan, Willems, Stefan M, de Visser, Leonie, Ligtenberg, Marjolijn J L

“…The diagnostic landscape of non-small cell lung cancer (NSCLC) is changing rapidly with the availability of novel treatments. Despite high-level healthcare in…”
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EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma by Smits, Alexander J. J., Kummer, J. Alain, Hinrichs, John W. J., Herder, Gerarda J. M., Scheidel-Jacobse, Karen C., Jiwa, N. Mehdi, Ruijter, T. Emiel G., Nooijen, Peet T. G. A., Looijen-Salamon, Monica G., Ligtenberg, Marjolijn J. L., Thunnissen, Frederik B., Heideman, Daniëlle A. M., de Weger, Roel A., Vink, Aryan

“…Background Frequencies of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC) have predominantly been determined in East Asian and North American…”
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Sociodemographic Characteristics and Screening Outcomes of Women Preferring Self-Sampling in the Dutch Cervical Cancer Screening Programme: A Population-Based Study by Aitken, Clare A, Inturrisi, Federica, Kaljouw, Sylvia, Nieboer, Daan, Siebers, Albert G, Melchers, Willem J G, van den Brule, Adriaan J C, Molijn, Anco, Hinrichs, John W J, Niesters, Hubert G M, van Kemenade, Folkert J, Berkhof, Johannes, de Kok, Inge M C M

“…In the Netherlands, lower high-risk human papillomavirus (hrHPV) positivity but higher cervical intraepithelial neoplasia (CIN) 2+ detection were found in…”
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Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material by de Leng, Wendy W J, Gadellaa-van Hooijdonk, Christa G, Barendregt-Smouter, Françoise A S, Koudijs, Marco J, Nijman, Ies, Hinrichs, John W J, Cuppen, Edwin, van Lieshout, Stef, Loberg, Robert D, de Jonge, Maja, Voest, Emile E, de Weger, Roel A, Steeghs, Neeltje, Langenberg, Marlies H G, Sleijfer, Stefan, Willems, Stefan M, Lolkema, Martijn P

“…Targeted Next Generation Sequencing (NGS) offers a way to implement testing of multiple genetic aberrations in diagnostic pathology practice, which is…”
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Therapeutic Drug Monitoring of Antidepressants and Cytochrome P450 Genotyping in General Practice by Kootstra-Ros, Jenny E., Van Weelden, Marga J. M., Hinrichs, John W. J., De Smet, Peter A. G. M., van der Weide, Jan

“…In the psychiatric setting, therapeutic drug monitoring and genotyping for cytochrome P450 (CYP) polymorphisms help to ensure and maintain therapeutic drug…”
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Clinical performance of high-risk HPV testing on self-samples versus clinician samples in routine primary HPV screening in the Netherlands: An observational study by Inturrisi, Federica, Aitken, Clare A., Melchers, Willem J.G., van den Brule, Adriaan J.C., Molijn, Anco, Hinrichs, John W.J., Niesters, Hubert G.M., Siebers, Albert G., Schuurman, Rob, Heideman, Daniëlle A.M., de Kok, Inge M.C.M., Bekkers, Ruud L.M., van Kemenade, Folkert J., Berkhof, Johannes

“…High-risk human papillomavirus (hrHPV) testing on self-collected samples has potential as a primary screening tool in cervical screening, but real-world…”
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Comparison of Next-Generation Sequencing and Mutation-Specific Platforms in Clinical Practice by Hinrichs, John W. J., Marja van Blokland, W. T., Moons, Michiel J., Radersma, Remco D., Radersma-van Loon, Joyce H., de Voijs, Carmen M. A., Rappel, Sophie B., Koudijs, Marco J., Besselink, Nicolle J. M., Willems, Stefan M., de Weger, Roel A.

“…Objectives: To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity,…”
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Simultaneous Detection of Clinically Relevant Mutations and Amplifications for Routine Cancer Pathology by Hoogstraat, Marlous, Hinrichs, John W.J, Besselink, Nicolle J.M, Radersma-van Loon, Joyce H, de Voijs, Carmen M.A, Peeters, Ton, Nijman, Isaac J, de Weger, Roel A, Voest, Emile E, Willems, Stefan M, Cuppen, Edwin, Koudijs, Marco J

“…In routine cancer molecular pathology, various independent experiments are required to determine mutation and amplification status of clinically relevant…”
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ATP-binding Cassette Transporters Are Enriched in Non-caveolar Detergent-insoluble Glycosphingolipid-enriched Membrane Domains (DIGs) in Human Multidrug-resistant Cancer Cells by Hinrichs, John W.J., Klappe, Karin, Hummel, Ina, Kok, Jan W.

“…In this study we show that P-glycoprotein in multidrug-resistant 2780AD human ovarian carcinoma cells and multidrug resistance-associated protein 1 in…”
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MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells by Klappe, Karin, Hinrichs, John W.J., Kroesen, Bart‐Jan, Sietsma, Hannie, Kok, Jan Willem

“…Previously we have described a novel multidrug‐resistant cell line, HT29col, which displayed over expression of the multidrug‐resistance protein 1 (MRP1) and…”
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Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains by Hinrichs, John W. J, Klappe, Karin, Riezen, Manon van, Kok, Jan W

“…We have recently shown that two ATP binding cassette (ABC) transporters are enriched in Lubrol-resistant noncaveolar membrane domains in multidrug-resistant…”
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Introduction of primary screening using high-risk HPV DNA detection in the Dutch cervical cancer screening programme: a population-based cohort study by Aitken, Clare A, van Agt, Heleen M E, Siebers, Albert G, van Kemenade, Folkert J, Niesters, Hubert G M, Melchers, Willem J G, Vedder, Judith E M, Schuurman, Rob, van den Brule, Adriaan J C, van der Linden, Hans C, Hinrichs, John W J, Molijn, Anco, Hoogduin, Klaas J, van Hemel, Bettien M, de Kok, Inge M C M

“…In January 2017, the Dutch cervical cancer screening programme transitioned from cytomorphological to primary high-risk HPV (hrHPV) DNA screening, including…”
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The influence of cytochrome P450 pharmacogenetics on disposition of common antidepressant and antipsychotic medications by van der Weide, Jan, Hinrichs, John W J

“…Since the identification of all the major drug-metabolising cytochrome P450 (CYP) enzymes and their major gene variants, pharmacogenetics has had a major…”
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Detection of CYP2D6 polymorphisms 9, 10, and 41 using ARMS-PCR and their allelic frequencies in 400 psychiatric patients by Hinrichs, John W J, Smallegoor, Windy D, van Baalen-Benedek, Erica H, Welker, Chris, van der Weide, Jan

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Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material: e0149405 by Leng, W Jde, Hooijdonk, Christa GGadellaa-van, Barendregt-Smouter, Francoise AS, Koudijs, Marco J, Nijman, Ies, Hinrichs, John WJ, Cuppen, Edwin, Lieshout, Stef van, Loberg, Robert D, Jonge, Maja de

“…Background Targeted Next Generation Sequencing (NGS) offers a way to implement testing of multiple genetic aberrations in diagnostic pathology practice, which…”
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