Search Results - "Hinrichs, Gitte R"

Mechanisms of sodium retention in nephrotic syndrome by Hinrichs, Gitte R., Jensen, Boye L., Svenningsen, Per

“…PURPOSE OF REVIEWProteinuria in nephrotic syndrome is associated with sodium retention and edema. Recent studies from mice, rats and humans have shown that the…”
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Urokinase‐type plasminogen activator contributes to amiloride‐sensitive sodium retention in nephrotic range glomerular proteinuria in mice by Hinrichs, Gitte R., Weyer, Kathrin, Friis, Ulla G., Svenningsen, Per, Lund, Ida K., Nielsen, Rikke, Mollet, Géraldine, Antignac, Corinne, Bistrup, Claus, Jensen, Boye L., Birn, Henrik

“…Aim Activation of sodium reabsorption by urinary proteases has been implicated in sodium retention associated with nephrotic syndrome. The study was designed…”
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The GLP-1-mediated gut-kidney cross talk in humans: mechanistic insight by Hinrichs, Gitte R, Hovind, Peter, Asmar, Ali

“…Incretin-based therapy is an antidiabetic and antiobesity approach mimicking glucagon-like peptide-1 (GLP-1) with additional end-organ protection. This review…”
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Water In and Water Out—Or Just the Opposite? The Need to Understand Our Patients’ Illnesses in Their Own Words by Hinrichs, Gitte R., Mortensen, Line Aas

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Optimizing diuretic treatment of patients with edema and nephrotic syndrome by Hinrichs, Gitte R., Jensen, Boye L.

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Reverse Phenotypes of Patients with Genetically Confirmed Liddle Syndrome by Granhøj, Jeff, Nøhr, Thomas K, Hinrichs, Gitte R, Rasmussen, Maria, Svenningsen, Per

“…Liddle syndrome was initially characterized by hypertension, hypokalemia, metabolic alkalosis, and suppressed plasma renin and aldosterone, resulting from…”
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A mini-review of pharmacological strategies used to ameliorate polyuria associated with X-linked nephrogenic diabetes insipidus by Mortensen, Line A, Bistrup, Claus, Jensen, Boye L, Hinrichs, Gitte R

“…Nephrogenic diabetes insipidus (NDI) is characterized by renal resistance to the antidiuretic hormone arginine vasopressin (AVP), which leads to polyuria,…”
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ACE2 and TMPRSS2 in human kidney tissue and urine extracellular vesicles with age, sex, and COVID-19 by Bach, Marie Lykke, Laftih, Sara, Andresen, Jesper K, Pedersen, Rune M, Andersen, Thomas Emil, Madsen, Lone W, Madsen, Kirsten, Hinrichs, Gitte R, Zachar, Rikke, Svenningsen, Per, Lund, Lars, Johansen, Isik S, Hansen, Lennart Friis, Palarasah, Yaseelan, Jensen, Boye L

“…SARS-CoV-2 virus infects cells by engaging with ACE2 requiring protease TMPRSS2. ACE2 is highly expressed in kidneys. Predictors for severe disease are high…”
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Albuminuria in kidney transplant recipients is associated with increased urinary serine proteases and activation of the epithelial sodium channel by Hinrichs, Gitte R, Michelsen, Jannie S, Zachar, Rikke, Friis, Ulla G, Svenningsen, Per, Birn, Henrik, Bistrup, Claus, Jensen, Boye L

“…Albuminuria predicts adverse renal outcome in kidney transplant recipients. The present study addressed the hypothesis that albuminuria is associated with…”
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Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients by Isaksson, Gustaf L, Nielsen, Marie B, Hinrichs, Gitte R, Krogstrup, Nicoline V, Zachar, Rikke, Stubmark, Heidi, Svenningsen, Per, Madsen, Kirsten, Bistrup, Claus, Jespersen, Bente, Birn, Henrik, Palarasah, Yaseelan, Jensen, Boye L

“…Proteinuria predicts accelerated decline in kidney function in kidney transplant recipients (KTRs). We hypothesized that aberrant filtration of complement…”
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Amiloride resolves resistant edema and hypertension in a patient with nephrotic syndrome; a case report by Hinrichs, Gitte R., Mortensen, Line A., Jensen, Boye L., Bistrup, Claus

“…Sodium and fluid retention is a hallmark and a therapeutic challenge of the nephrotic syndrome (NS). Studies support the “overfill” theory of NS with…”
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Sodium retention by uPA‐plasmin‐ENaC in nephrotic syndrome—Authors reply by Hinrichs, Gitte R., Weyer, Kathrin, Friis, Ulla G., Svenningsen, Per, Lund, Ida Katrine, Nielsen, Rikke, Mollet, Géraldine, Antignac, Corinne, Bistrup, Claus, Jensen, Boye L., Birn, Henrik

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A Novel AQP2 Sequence Variant Causing Aquaporin-2 Retention in the Cytoplasm and Autosomal Dominant Nephrogenic Diabetes Insipidus by Hinrichs, Gitte R., Baltzer, Sandrine, Pallien, Tamara, Svenningsen, Per, Dalgaard, Emil B., Hertz, Jens Michael, Bistrup, Claus, Jensen, Boye L., Klussmann, Enno

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Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin by Oxlund, Christina, Kurt, Birgül, Schwarzensteiner, Ilona, Hansen, Mie R., Stæhr, Mette, Svenningsen, Per, Jacobsen, Ib A., Hansen, Pernille B., Thuesen, Anne D., Toft, Anja, Hinrichs, Gitte R., Bistrup, Claus, Jensen, Boye L.

“…The proteinase prostasin is a candidate mediator for aldosterone-driven proteolytic activation of the epithelial sodium channel (ENaC). It was hypothesized…”
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Treatment of Nephrogenic Diabetes Insipidus Patients With cGMP-Stimulating Drugs Does Not Mitigate Polyuria or Increase Urinary Concentrating Ability by Hinrichs, Gitte R., Mortensen, Line A., Bistrup, Claus, Dieperink, Hans H., Jensen, Boye L.

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A novel mutation affecting the arginine‐137 residue of AVPR2 in dizygous twins leads to nephrogenic diabetes insipidus and attenuated urine exosome aquaporin‐2 by Hinrichs, Gitte R., Hansen, Louise H., Nielsen, Maria R., Fagerberg, Christina, Dieperink, Hans, Rittig, Søren, Jensen, Boye L.

“…Mutations in the vasopressin V2 receptor gene AVPR2 may cause X‐linked nephrogenic diabetes insipidus by defective apical insertion of aquaporin‐2 in the renal…”
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SP163NEPHROTIC RANGE PROTEINURIA AND SODIUM RETENTION IN MICE IS ASSOCIATED WITH INCREASED URINARY PROTEASE ACTIVITY AND ENAC ACTIVATION by Hinrichs, Gitte R., Weyer, Kathrin, Friis, Ulla G., Nielsen, Rikke, Mollet, Géraldine, Antignac, Corinne, Bistrup, Claus, Jensen, Boye L., Birn, Henrik

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Amiloride resolves resistant edema and hypertension in a patient with nephrotic syndrome; a case report by Hinrichs, Gitte R, Mortensen, Line A, Jensen, Boye L, Bistrup, Claus

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