Search Results - "Hinoi, T"

Oxaliplatin and molecular-targeted drug therapies improved the overall survival in colorectal cancer patients with synchronous peritoneal carcinomatosis undergoing incomplete cytoreductive surgery by Adachi, T., Hinoi, T., Egi, H., Shimomura, M., Ohdan, H.

“…Purpose To estimate the feasibility and limitations of incomplete cytoreductive surgery and modern systemic chemotherapy in patients with synchronous…”
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KRAS mutation leads to decreased expression of regulator of calcineurin 2, resulting in tumor proliferation in colorectal cancer by Niitsu, H, Hinoi, T, Kawaguchi, Y, Sentani, K, Yuge, R, Kitadai, Y, Sotomaru, Y, Adachi, T, Saito, Y, Miguchi, M, Kochi, M, Sada, H, Shimomura, M, Oue, N, Yasui, W, Ohdan, H

“…KRAS mutations occur in 30–40% of all cases of human colorectal cancer (CRC). However, to date, specific therapeutic agents against KRAS -mutated CRC have not…”
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2129 Predictive factor for toxicities and treatment termination in adjuvant capecitabine therapy for stage III colorectal cancer; based on the data of a randomized trial, JCOG0910 by Yoshida, Y, Yamazaki, K, Mizusawa, J, Satoh, M, Hinoi, T, Tsuchida, A, Otsuka, K, Sato, T, Watanabe, M, Baba, H, Kimura, H, Idani, H, Kanazawa, A, Fukunaga, M, Okuda, J, Tajima, Y, Hasegawa, H, Katayama, H, Hamaguchi, T, Shimada, Y

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Loss of CDX2 Expression and Microsatellite Instability Are Prominent Features of Large Cell Minimally Differentiated Carcinomas of the Colon by Hinoi, Takao, Tani, Masachika, Lucas, Peter C., Caca, Karel, Dunn, Rodney L., Macri, Ettore, Loda, Massimo, Appelman, Henry D., Cho, Kathleen R., Fearon, Eric R.

“…Most large bowel cancers are moderately to well-differentiated adenocarcinomas comprised chiefly or entirely of glands lined by tall columnar cells. We have…”
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Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system by Qualtrough, D, Hinoi, T, Fearon, E, Paraskeva, C

“…Background: The Cdx genes are expressed in the colorectal epithelium and are frequently downregulated during tumorigenesis. Overexpression of Cdx genes has…”
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Helicobacter pylori‐induced atrophic gastritis progressing to gastric cancer exhibits sonic hedgehog loss and aberrant CDX2 expression by SHIOTANI, A., IISHI, H., UEDO, N., ISHIHARA, R., ISHIGURO, S., TATSUTA, M., NAKAE, Y., KUMAMOTO, M., HINOI, T., MERCHANT, J. L.

“…Summary Background The loss of sonic hedgehog is an early change that occurs in the mucosa prior to neoplastic transformation and correlates with the type of…”
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Single-Incision Laparoscopic Colectomy Using the Gelport System for Early Colon Cancer by Egi, H., Okajima, M., Hinoi, T., Takakura, Y., Kawaguchi, Y., Shimomura, M., Tokunaga, M., Adachi, T., Hattori, M., Urushihara, T., Itamoto, T., Ohdan, H.

“…Background Laparoscopic surgery has spread quickly during the past twenty years, and has become one of the important treatments in the field of colorectal…”
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QS284. Risk Factors for Anastomotic Leakage Following Laparoscopic Surgery of Middle and Low Rectal Cancers: Multicenter Study by Japan Society of Laparoscopic Colorectal Surgery by Hinoi, T, Okajima, M, Ikeda, S, Yoshimitsu, M, Konishi, F, Watanabe, M

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Clinicopathological characteristics of upper tract urothelial cancer with loss of immunohistochemical expression of mismatch repair proteins by Hayashi, T., Ikeda, K., Taniyama, D., Hsi, R.S., Inoue, S., Teishima, J., Akabane, S., Sentani, K., Yasui, W., Yamamoto, H., Kuraoka, K., Hinoi, T.

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FSHD / OPMD / MYOTONIC DYSTROPHY: P.238 Colorectal cancer occurs as the extramuscular manifestation of elderly FSHD patients by Kurashige, T., Morino, H., Ueno, H., Murao, T., Watanabe, T., Hinoi, T., Nishino, I., Maruyama, H., Torii, T.

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FSHD / OPMD / MYOTONIC DYSTROPHY by Kurashige, T., Morino, H., Ueno, H., Murao, T., Watanabe, T., Hinoi, T., Nishino, I., Maruyama, H., Torii, T.

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Multicenter phase II study of biweekly XELIRI plus bevacizumab as a second-line therapy in patients with metastatic colorectal cancer (JSWOG-C3 study) by Mori, Y., Suzuki, N., Nagasaka, T., Tanioka, H., Iwamoto, Y., Neki, Y., Yamatsuji, T., Kobayashi, M., Nakajima, M., Ojima, Y., Ikeda, S., Kawamoto, K., Shinozaki, K., Tsuji, A., Hinoi, T., Yamaguchi, Y., Yamashita, K., Shimokawa, M., Okajima, M., Hazama, S.

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CDX2 regulates liver intestine–cadherin expression in normal and malignant colon epithelium and intestinal metaplasia by Hinoi, Takao, Lucas, Peter C., Kuick, Rork, Hanash, Samir, Cho, Kathleen R., Fearon, Eric R.

“…Background & Aims: The intestine-specific caudal-related homeobox transcription factor CDX2 seems to play a key role in intestinal development and…”
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Effect of pretreatment with coenzyme Q10 and monoclonal antibodies to adhesion molecules on ischemic small intestine preservation by Marubayashi, S, Matsusaka, C, Oshiro, Y, Maeda, T, Ikeda, M, Hinoi, T, Dohi, K

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Silencing of CDX2 Expression in Colon Cancer via a Dominant Repression Pathway by Hinoi, Takao, Loda, Massimo, Fearon, Eric R.

“…CDX2 is a caudal-related homeobox transcription factor whose expression in the adult is normally restricted to intestinal epithelium. Mice heterozygous for…”
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Complex Formation of Adenomatous Polyposis Coli Gene Product and Axin Facilitates Glycogen Synthase Kinase-3β-dependent Phosphorylation of β-Catenin and Down-regulates β-Catenin by Hinoi, Toshihide, Yamamoto, Hideki, Kishida, Michiko, Takada, Shinji, Kishida, Shosei, Kikuchi, Akira

“…Adenomatous polyposis coli gene product (APC) functions as a tumor suppressor and its mutations in familial adenomatous polyposis and colorectal cancers lead…”
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Acute Effect of Atorvastatin on Coronary Circulation Measured by Transthoracic Doppler Echocardiography in Patients Without Coronary Artery Disease by Angiography by Hinoi, Toshihide, Matsuo, Shusuke, Tadehara, Futoshi, Tsujiyama, Shuji, Yamakido, Michio

“…Thirty-two patients were randomly assigned to treatment with placebo or atorvastatin. The time-averaged peak diastolic velocity (APDV) of the left anterior…”
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Identification and Characterization of a Novel Protein Interacting with Ral-binding Protein 1, a Putative Effector Protein of Ral by Ikeda, Masahiro, Ishida, Osamu, Hinoi, Takao, Kishida, Shosei, Kikuchi, Akira

“…Ral-binding protein 1 (RalBP1) is a putative effector protein of Ral and exhibits a GTPase activating activity for Rac and CDC42. To clarify the function of…”
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CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium by Hinoi, Takao, Gesina, Galina, Akyol, Aytekin, Kuick, Rork, Hanash, Samir, Giordano, Thomas J., Gruber, Stephen B., Fearon, Eric R.

“…Background & Aims: The homeobox transcription factor CDX2 has a key role in intestinal development and differentiation. Mice heterozygous for Cdx2 inactivation…”
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2.29 by Tadehara, F., Tsujiyama, S., Hinoi, T., Matsuo, S.

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