Search Results - "Hino, Kyosuke"
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Neofunction of ACVR1 in fibrodysplasia ossificans progressiva
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-2015)“…Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by extraskeletal bone formation through endochondral ossification. FOP…”
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Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
Published in The Journal of clinical investigation (01-09-2017)“…Fibrodysplasia ossificans progressiva (FOP) is a rare and intractable disease characterized by extraskeletal bone formation through endochondral ossification…”
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New Protocol to Optimize iPS Cells for Genome Analysis of Fibrodysplasia Ossificans Progressiva
Published in Stem cells (Dayton, Ohio) (01-06-2015)“…Successful in vitro disease‐recapitulation using patient‐specific induced pluripotent stem cells (iPSCs) requires two fundamental technical issues: appropriate…”
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An mTOR Signaling Modulator Suppressed Heterotopic Ossification of Fibrodysplasia Ossificans Progressiva
Published in Stem cell reports (13-11-2018)“…Fibrodysplasia ossificans progressiva (FOP) is a rare and intractable disorder characterized by extraskeletal bone formation through endochondral ossification…”
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Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks
Published in Development (Cambridge) (01-08-2004)“…Achieving a real understanding of animal development obviously requires a comprehensive rather than partial identification of the genes working in each…”
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Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds
Published in Molecular pharmacology (01-03-2016)“…Transient receptor potential canonical (TRPC) proteins form Ca(2+)-permeable cation channels activated upon stimulation of metabotropic receptors coupled to…”
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Screening for Adiponectin Secretion Regulators
Published in Vitamins and Hormones (2012)“…Adiponectin is an adipokine secreted from adipocytes and plays important roles in the suppression of metabolic syndromes that can result in type 2 diabetes,…”
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Book Chapter Journal Article -
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Application of disease-specific iPS cells for intractable diseases-from pathomechanisms to drug discovery
Published in Clinical calcium (01-04-2016)“…Genetic diseases affecting bone and cartilage, which are main components of the locomotive system, are extremely diverse. Even if the causative genes are…”
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Screening for Adiponectin Secretion Regulators: Adiponectin
Published in Vitamins and hormones (2012)Get full text
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High-throughput screening for small-molecule adiponectin secretion modulators
Published in Journal of biomolecular screening (01-07-2011)“…Adiponectin is an adipokine secreted by adipocytes and plays a role in the suppression of metabolic disorders that can result in type 2 diabetes, obesity, and…”
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genomewide survey of developmentally relevant genes in Ciona intestinalis : VI. Genes for Wnt, TGFβ, Hedgehog and JAK/STAT signaling pathways
Published in Development genes and evolution (01-06-2003)“…Cell–cell interactions play important roles in a variety of developmental processes, and therefore molecules involved in the signaling pathways have been…”
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A genomewide survey of developmentally relevant genes in Ciona intestinalis: VI. Genes for Wnt, TGF[beta], Hedgehog and JAK/STAT signaling pathways
Published in Development genes and evolution (01-06-2003)“…Cell-cell interactions play important roles in a variety of developmental processes, and therefore molecules involved in the signaling pathways have been…”
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A genomewide survey of developmentally relevant genes in Ciona intestinalis. VI. Genes for Wnt, TGFbeta, Hedgehog and JAK/STAT signaling pathways
Published in Development genes and evolution (01-06-2003)“…Cell-cell interactions play important roles in a variety of developmental processes, and therefore molecules involved in the signaling pathways have been…”
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