Search Results - "Hinnrasky, J."

Differentiated and functional human airway epithelium regeneration in tracheal xenografts by Dupuit, F, Gaillard, D, Hinnrasky, J, Mongodin, E, de Bentzmann, S, Copreni, E, Puchelle, E

“…To investigate the regeneration process of a well-differentiated and functional human airway epithelium, we adapted an in vivo xenograft model in which adult…”
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Dysregulation of IL‐2 and IL‐8 production in circulating T lymphocytes from young cystic fibrosis patients by HUBEAU, C., LE NAOUR, R., ABÉLY, M., HINNRASKY, J., GUENOUNOU, M., GAILLARD, D., PUCHELLE, E.

“…SUMMARY It is well documented that patients with cystic fibrosis (CF) are unable to clear persistent airway infections in spite of strong local inflammation,…”
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Early alterations in airway mucociliary clearance and inflammation of the lamina propria in CF mice by Zahm, J M, Gaillard, D, Dupuit, F, Hinnrasky, J, Porteous, D, Dorin, J R, Puchelle, E

“…In cystic fibrosis (CF), whether cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction leads to decreased mucociliary clearance and mucus…”
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Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands by Jacquot, J, Puchelle, E, Hinnrasky, J, Fuchey, C, Bettinger, C, Spilmont, C, Bonnet, N, Dieterle, A, Dreyer, D, Pavirani, A

“…Cystic fibrosis (CF) is caused by mutations in the gene coding for the CF transmembrane conductance regulator (CFTR). From human normal tracheal submucosal…”
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Decreased expression of the CFTR protein in remodeled human nasal epithelium from non-cystic fibrosis patients by Brezillon, S, Dupuit, F, Hinnrasky, J, Marchand, V, Kälin, N, Tümmler, B, Puchelle, E

“…In normal adult pseudostratified human nasal surface epithelium, the cystic fibrosis transmembrane conductance regulator (CFTR) is localized to the apical…”
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Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium by Puchelle, E, Gaillard, D, Ploton, D, Hinnrasky, J, Fuchey, C, Boutterin, M C, Jacquot, J, Dreyer, D, Pavirani, A, Dalemans, W

“…Deletion of the amino acid residue Phe 508 of the cystic fibrosis transmembrane conductance regulator (CFTR) protein represents the most common mutation…”
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Expression of gelatinase A, a mediator of extracellular matrix remodeling, by tracheal gland serous cells in culture and in vivo by Tournier, J M, Polette, M, Hinnrasky, J, Beck, J, Werb, Z, Basbaum, C

“…Tracheal gland morphogenesis and gland hypertrophy in disease involve the penetration of epithelial cells into the submucosa, a process that requires digestion…”
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A change in gating mode leading to increased intrinsic Cl‐ channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease by Champigny, G., Imler, J.L., Puchelle, E., Dalemans, W., Gribkoff, V., Hinnrasky, J., Dott, K., Barbry, P., Pavirani, A., Lazdunski, M.

“…The effects of the mild cystic fibrosis (CF) mutation P574H were analysed and compared with those of three severe ones (delta I507, delta F508 and R560T)…”
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Tubule formation by human surface respiratory epithelial cells cultured in a three-dimensional collagen lattice by Benali, R, Tournier, J M, Chevillard, M, Zahm, J M, Klossek, J M, Hinnrasky, J, Gaillard, D, Maquart, F X, Puchelle, E

“…Human surface respiratory epithelial (HSRE) cells from nasal polyps have been cultured within collagen lattices in a serum-free defined medium. Cell growth…”
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Fibronectin and its alpha 5 beta 1-integrin receptor are involved in the wound-repair process of airway epithelium by Hérard, A L, Pierrot, D, Hinnrasky, J, Kaplan, H, Sheppard, D, Puchelle, E, Zahm, J M

“…The cell migration that occurs during wound repair is dependent on modifications of the cell-matrix interaction in which extracellular matrix proteins and…”
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Embryonic Stem Cells Generate Airway Epithelial Tissue by Coraux, Christelle, Nawrocki-Raby, Beatrice, Hinnrasky, Jocelyne, Kileztky, Claire, Gaillard, Dominique, Dani, Christian, Puchelle, Edith

“…Embryonic stem (ES) cells are self-renewable and pluripotent cells derived from the inner cell mass of a blastocyst-stage embryo. ES cell pluripotency is being…”
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Expression and localization of CFTR in the rhesus monkey surface airway epithelium by Dupuit, F, Bout, A, Hinnrasky, J, Fuchey, C, Zahm, J M, Imler, J L, Pavirani, A, Valerio, D, Puchelle, E

“…The Rhesus monkey has been used as a model for evaluating the possibility of introducing the CFTR gene into the airway epithelium in vivo. We addressed the…”
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Reconstituted Skin from Murine Embryonic Stem Cells by Coraux, Christelle, Hilmi, Caroline, Rouleau, Matthieu, Spadafora, Anne, Hinnrasky, Jocelyne, Ortonne, Jean-Paul, Dani, Christian, Aberdam, Daniel

“…Embryonic stem (ES) cell lines can be expanded indefinitely in culture while maintaining their potential to differentiate into any cell type [1, 2]. During…”
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Inflammation and Infection in Naive Human Cystic Fibrosis Airway Grafts by Tirouvanziam, Rabindra, de Bentzmann, Sophie, Hubeau, Cedric, Hinnrasky, Jocelyne, Jacquot, Jacky, Peault, Bruno, Puchelle, Edith

“…Exacerbated inflammation is now recognized as an important component of cystic fibrosis (CF) airway disease. Whether inflammation is part of the basic defect…”
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Aquaporin‐3 Expression in Human Fetal Airway Epithelial Progenitor Cells by Avril‐Delplanque, Aurélie, Casal, Ibrahim, Castillon, Nicolas, Hinnrasky, Jocelyne, Puchelle, Edith, Péault, Bruno

“…Airway epithelium stem cells have not yet been prospectively identified, but it is generally assumed that both secretory and basal cells have the capacity to…”
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Production of lipocortin-like proteins by cultured human tracheal submucosal gland cells by Jacquot, J., Dupuit, F., Elbtaouri, H., Hinnrasky, J., Antonicelli, F., Haye, B., Puchelle, E.

“…Evidence is obtained for the presence of lipocortin-like proteins in human tracheal gland cells in culture. Using polyclonal antibodies to lipocortin I…”
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Differentiation of human surface upper airway epithelial cells in primary culture on a floating collagen gel by Chevillard, M, Hinnrasky, J, Pierrot, D, Zahm, J M, Klossek, J M, Puchelle, E

“…The differentiation of human nasal surface epithelial cells in primary three-dimensional (3D) culture was studied. The dissociated cells were seeded on type I…”
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Tubule formation and functional differentiation by human epithelial respiratory cells cultured in a three-dimensional collagen matrix by Benali, R, Chevillard, M, Zahm, J M, Hinnrasky, J, Klossek, J M, Puchelle, E

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Stimulation of beta 2-adrenergic receptor increases cystic fibrosis transmembrane conductance regulator expression in human airway epithelial cells through a cAMP/protein kinase A-independent pathway by Taouil, Karima, Hinnrasky, Jocelyne, Hologne, Coralie, Corlieu, Pascal, Klossek, Jean-Michel, Puchelle, Edith

“…PSD-95/Dlg-A/ZO-1 (PDZ) domains play an essential role in determining cell polarity. The Na(+)/H(+) exchanger regulatory factor (NHERF), also known as EBP50,…”
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Selective Up-Regulation of Chemokine IL-8 Expression in Cystic Fibrosis Bronchial Gland Cells in Vivo and in Vitro by Tabary, Olivier, Zahm, Jean Marie, Hinnrasky, Jocelyne, Couetil, Jean Paul, Cornillet, Pascale, Guenounou, Moncef, Gaillard, Dominique, Puchelle, Edith, Jacquot, Jacky

“…Accumulating evidence suggests that the early pulmonary inflammation pathogenesis in cystic fibrosis (CF) may be associated with an abnormal increase in the…”
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