Search Results - "Hinkle, Robert J"

BiBr3-Initiated Tandem Addition/Silyl-Prins Reactions to 2,6-Disubstituted Dihydropyrans by Lian, Yajing, Hinkle, Robert J

“…A tandem addition/silyl-Prins reaction efficiently affords cis-2,6-disubstituted dihydropyrans (DHPs) using 5 mol % of BiBr3 in CH2Cl2. The reaction occurs…”
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Stereoselective Construction of Cyclic Ethers Using a Tandem Two-Component Etherification:  Elucidation of the Role of Bismuth Tribromide by Evans, P. Andrew, Cui, Jian, Gharpure, Santosh J, Hinkle, Robert J

“…The stereodivergent construction of cyclic ethers remains an important area of synthetic interest, particularly given the ubiquity of C-glycoside derivatives…”
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Mild, Modular, and Convergent Synthesis of Helical Naphtho[2,1‑c]chromenes via a Multistep Cyclization/Aromatization Cascade Sequence by Hinkle, Robert J, Speer, Daniel J, Carnell, Brendon B, Kanter, Bethany L, Pike, Robert D

“…Tetracyclic 6H-naphtho­[2,1-c]­chromenes are expeditiously synthesized through a BF3·OEt2-mediated, three-step cascade reaction, creating new central pyran and…”
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Atom Economical, One-Pot, Three-Reaction Cascade to Novel Tricyclic 2,4-Dihydro‑1H‑benzo[f]isochromenes by Hinkle, Robert J, Lewis, Shane E

“…Reaction of 6-methyl-1-phenylhept-3-yne-2,6-diol with various aldehydes under Lewis acid conditions provides an atom economical, two-component cascade reaction…”
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Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings by Hale, Emma A., Ryan, Hannah M., McOsker, Alexandra M., Funk, Cody M., Green, Lauren C., Mazur, Lauren E., Uthappa, Diya M., Flood, Brian M., Young, Douglas D., Hinkle, Robert J.

“…Antibiotic resistance is a growing problem facing global societies today. Many new antibiotics are derivatized versions of already existing antibiotics, which…”
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Electrophilic Cyclization of Phenylalkynediols to Naphthyl(aryl)iodonium Triflates with Chelating Hydroxyls: Preparation and X‑ray Analyses by Hinkle, Robert J, Bredenkamp, Sarah E, Pike, Robert D, Cheon, Seong Ik

“…Alkynediols containing one propargylic alcohol as well as a second alcohol, which is propargylic or homopropargylic, react with PhI+CN–OTf (Stang’s reagent) or…”
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Bi(OTf)3-, TfOH-, and TMSOTf-Mediated, One-Pot Epoxide Rearrangement, Addition, and Intramolecular Silyl-Modified Sakurai (ISMS) Cascade toward Dihydropyrans: Comparison of Catalysts and Role of Bi(OTf)3 by Lambert, R. Frederick, Hinkle, Robert J, Ammann, Stephen E, Lian, Yajing, Liu, Jia, Lewis, Shane E, Pike, Robert D

“…Catalytic quantities of bismuth(III) triflate efficiently initiate the rearrangement of epoxides to aldehydes, which subsequently react with…”
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Structural and Electronic Characteristics of Thienyl(aryl)iodonium Triflates by Bykowski, Darren, McDonald, Robert, Hinkle, Robert J, Tykwinski, Rik R

“…A general strategy toward the synthesis of aryliodonium triflate salts has been exploited to afford derivatives that incorporate thiophene and bithiophene…”
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Palladium(II) and copper(I) cocatalyzed coupling of stereodefined alkenyl(phenyl)iodonium triflates and unsaturated tri-n-butylstannanes by Hinkle, Robert J, Poulter, Gregory T, Stang, Peter J

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Synthesis of 2,6-disubstituted dihydropyrans via an efficient BiBr3-initiated three component, one-pot cascade by HINKLE, Robert J, YAJING LIAN, SPEIGHT, Lee C, STEVENSON, Heather E, SPRACHMAN, Melissa M, KATKISH, Lauren A, MATTERN, M. Christa

“…The rapid synthesis of cis- 2,6-disubstituted dihydropyrans is achieved in a three-component, one-pot cascade reaction. BiBr 3 -ediated addition of ketene…”
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Primary Vinyl Cations in Solution:  Kinetics and Products of β,β-Disubstituted Alkenyl(aryl)iodonium Triflate Fragmentations by Hinkle, Robert J, McNeil, Anne J, Thomas, Quinn A, Andrews, Marie N

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Atom Economical, One-Pot, Three-Reaction Cascade to Novel Tricyclic 2,4-Dihydro-1 H -benzo[ f ]isochromenes by Hinkle, Robert J., Lewis, Shane E.

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Facile Fragmentations of Alkenyl(aryl)iodonium Triflates by Hinkle, Robert J, Thomas, David B

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Vinyl Carbocations:  Solution Studies of Alkenyl(aryl)iodonium Triflate Fragmentations by McNeil, Anne J, Hinkle, Robert J, Rouse, E. Ashley, Thomas, Quinn A, Thomas, David B

“…Generation of vinyl cations is facile by fragmentation of alkenyl(aryl)iodonium trifluoromethanesulfonates. Kinetics and electronic effects were probed by 1H…”
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Fragmentations of (E)- and (Z)- isomers of 2-methylbuten-1-yl(aryl)iodonium triflates: competing mechanisms for enol triflate formation by Hinkle, Robert J., Mikowski, Ann M.

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(Z)-2-Methylbuten-1-yl(aryl)iodonium trifluoromethanesulfonates containing electron-withdrawing groups on the aryl moiety by Hinkle, Robert J., McDonald, Robert

“…The crystal structures of [(Z)‐2‐methyl­but‐1‐en‐1‐yl]­[4‐(tri­fluoro­methyl)­phenyl]­iodo­nium tri­fluoro­methane­sulfonate, C12H13F3I+·CF3O3S−, (I),…”
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Addition of Benzylzinc Halides to Alkenyl(phenyl)iodonium Triflates:  Stereoselective Synthesis of Trisubstituted Alkenes by Hinkle, Robert J, Leri, Alessandra C, David, Geoffrey A, Erwin, Whitney M

“…Benzylic organozinc reagents generated by insertion of zinc metal into benzyl−bromine bonds react with alkenyl(phenyl)iodonium triflates to provide single…”
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Primary Vinyl Cations in Solution:  Kinetics and Products of β, β-Disubstituted Alkenyl(aryl)iodonium Triflate Fragmentations [J. Am. Chem. Soc. 1999, 121, 7437−7438] by Hinkle, Robert J, McNeil, Anne J, Thomas, Quinn A, Andrews, Marie N

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Vinylphosphonium salts: stereoselective palladium-catalyzed vinylation of triphenylphosphine with vinyl triflates by Hinkle, Robert J, Stang, Peter J, Kowalski, Mark H

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Vinylplatinum carbenes and nitriles, platinoxacyclic complexes, and Heck-type coupling products formed via reaction of (.sigma.-2-propenyl)bis(triphenylphosphine)platinum(II) triflate with alkynols, nitriles, and acrylate esters. Molecular structure of [cyclic] [(PPh3)2PtCH2C(O)OCH3][OTf] by Hinkle, Robert J, Stang, Peter J, Arif, Atta M

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