Search Results - "Hink, U"

The German CPU registry: Comparison of smokers and nonsmokers by Bock, D., Senges, J., Pohlmann, C., Hochadel, M., Münzel, T., Giannitsis, E., Schmitt, C., Heusch, G., Voigtländer, T., Mudra, H., Schumacher, B., Darius, H., Maier, L. S., Hailer, B., Haude, M., Gohlke, H., Hink, U.

“…Background Chest pain is a major reason for admission to an internal emergency department, and smoking is a well-known risk factor for coronary artery disease…”
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Immediate effect of the MitraClip procedure on mitral ring geometry in primary and secondary mitral regurgitation by Schmidt, Frank Patrick, von Bardeleben, Ralph Stephan, Nikolai, Philipp, Jabs, Alexander, Wunderlich, Nina, Münzel, Thomas, Hink, Ulrich, Warnholtz, Ascan

“…Percutaneous treatment of mitral regurgitation (MR) has been shown to reduce MR severity and improve functional outcomes. Surgical treatment of MR usually…”
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Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus by Hink, Ulrich, Li, Huige, Mollnau, Hanke, Oelze, Mathias, Matheis, Edi, Hartmann, Mark, Skatchkov, Mikhail, Thaiss, Friedrich, Stahl, Rolf A.K, Warnholtz, Ascan, Meinertz, Thomas, Griendling, Kathy, Harrison, David G, Forstermann, Ulrich, Munzel, Thomas

“…ABSTRACT —Incubation of endothelial cells in vitro with high concentrations of glucose activates protein kinase C (PKC) and increases nitric oxide synthase…”
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Sex‐based differences in outcomes with bivalirudin or unfractionated heparin for transcatheter aortic valve replacement: Results from the BRAVO‐3 randomized trial by Asgar, A., Chandrasekhar, J., Mikhail, G., Webb, J., Lefèvre, T., Tamburino, C., Hildick‐Smith, D., Hambrecht, R., Van Belle, E., Widder, J., Dumonteil, N., Hink, U, Jeger, R., Linke, A., Deliargyris, E., Gao, P., Mehran, R., Hengstenberg, C., Anthopoulos, P., Dangas, G.

“…Background Women comprise almost 50% of patients undergoing transcatheter aortic valve replacement (TAVR) and previous studies have indicated higher rates of…”
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Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH‐2−/− mice by Wenzel, P, Hink, U, Oelze, M, Seeling, A, Isse, T, Bruns, K, Steinhoff, L, Brandt, M, Kleschyov, A L, Schulz, E, Lange, K, Weiner, H, Lehmann, J, Lackner, K J, Kawamoto, T, Münzel, T, Daiber, A

“…Background and purpose: Mitochondrial aldehyde dehydrogenase (ALDH‐2) has been shown to provide a pathway for bioactivation of organic nitrates and to be prone…”
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Effects of Long-Term Nitroglycerin Treatment on Endothelial Nitric Oxide Synthase (NOS III) Gene Expression, NOS III–Mediated Superoxide Production, and Vascular NO Bioavailability by Münzel, Thomas, Li, Huige, Mollnau, Hanke, Hink, Ulrich, Matheis, Edi, Hartmann, Mark, Oelze, Mathias, Skatchkov, Mikhail, Warnholtz, Ascan, Duncker, Linda, Meinertz, Thomas, Förstermann, Ulrich

“…Long-term nitroglycerin (NTG) treatment has been shown to be associated with cross-tolerance to endothelium-dependent vasodilators. It may involve increased…”
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The importance of the Heart Team evaluation before transcatheter aortic valve replacement: Results from the BRAVO‐3 trial by Camaj, Anton, Claessen, Bimmer E., Mehran, Roxana, Yudi, Matias B., Power, David, Baber, Usman, Hengstenberg, Christian, Lefevre, Thierry, Van Belle, Eric, Giustino, Gennaro, Guedeney, Paul, Sorrentino, Sabato, Kupatt, Christian, Webb, John G., Hildick‐Smith, David, Hink, Hans U., Deliargyris, Efthymios N., Anthopoulos, Prodromos, Sharma, Samin K., Kini, Annapoorna, Sartori, Samantha, Chandrasekhar, Jaya, Dangas, George D.

“…Background/Objectives Clinicians use validated scores to risk‐stratify patients undergoing transcatheter aortic valve replacement (TAVR). However, evaluation…”
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Transkatheter-Klappenimplantation: TAVI bei Patienten mit niedrigem Risiko by Hink, U.

“…Originalpublikation Søndergaard L, Steinbrüchel D, Ihlemann N et al (2016) Two-year outcomes in patients with severe aortic valve stenosis randomized to…”
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1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease: The PLATFORM Study by Douglas, Pamela S, De Bruyne, Bernard, Pontone, Gianluca, Patel, Manesh R, Norgaard, Bjarne L, Byrne, Robert A, Curzen, Nick, Purcell, Ian, Gutberlet, Matthias, Rioufol, Gilles, Hink, Ulrich, Schuchlenz, Herwig Walter, Feuchtner, Gudrun, Gilard, Martine, Andreini, Daniele, Jensen, Jesper M, Hadamitzky, Martin, Chiswell, Karen, Cyr, Derek, Wilk, Alan, Wang, Furong, Rogers, Campbell, Hlatky, Mark A

“…Coronary computed tomographic angiography (CTA) plus estimation of fractional flow reserve using CTA (FFRCT) safely and effectively guides initial care over 90…”
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Quality-of-Life and Economic Outcomes of Assessing Fractional Flow Reserve With Computed Tomography Angiography: PLATFORM by Hlatky, Mark A, De Bruyne, Bernard, Pontone, Gianluca, Patel, Manesh R, Norgaard, Bjarne L, Byrne, Robert A, Curzen, Nick, Purcell, Ian, Gutberlet, Matthias, Rioufol, Gilles, Hink, Ulrich, Schuchlenz, Herwig Walter, Feuchtner, Gudrun, Gilard, Martine, Andreini, Daniele, Jensen, Jesper M, Hadamitzky, Martin, Wilk, Alan, Wang, Furong, Rogers, Campbell, Douglas, Pamela S

“…Fractional flow reserve estimated using computed tomography (FFRCT) might improve evaluation of patients with chest pain. The authors sought to determine the…”
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Extracellular superoxide dismutase, uric acid, and atherosclerosis by Hink, H U, Fukai, T

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ABSORB everolimus-eluting bioresorbable vascular scaffold systems for the sealing of unstable plaques by Gori, T., Qu, Z., Muxel, S., Hink, U., Schulz, E., Wenzel, P., Jabs, A., Munzel, T.

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Value of color doppler jet area for grading regurgitation severity in patients with secondary mitral regurgitation - better than its reputation? by Schmidt, F. P., Gniewosz, T., Jansen, T., Munzel, T., Hink, U., Von Bardeleben, R. S.

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The influence of age on outcomes after MitraClip therapy in the German mitral valve registry (TRAMI registry) by Schillinger, W., Baldus, S., Ouarrak, T., Bekeredjian, R., Boekstegers, P., Hink, U., Sievert, H., Schofer, J., Plicht, B., Senges, J.

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Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study by Douglas, Pamela S, Pontone, Gianluca, Hlatky, Mark A, Patel, Manesh R, Norgaard, Bjarne L, Byrne, Robert A, Curzen, Nick, Purcell, Ian, Gutberlet, Matthias, Rioufol, Gilles, Hink, Ulrich, Schuchlenz, Herwig Walter, Feuchtner, Gudrun, Gilard, Martine, Andreini, Daniele, Jensen, Jesper M, Hadamitzky, Martin, Chiswell, Karen, Cyr, Derek, Wilk, Alan, Wang, Furong, Rogers, Campbell, De Bruyne, Bernard

“…In symptomatic patients with suspected coronary artery disease (CAD), computed tomographic angiography (CTA) improves patient selection for invasive coronary…”
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Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance by Daiber, Andreas, Oelze, Matthias, Sulyok, Silke, Coldewey, Meike, Schulz, Eberhard, Treiber, Nicolai, Hink, Ulrich, Mülsch, Alexander, Scharffetter-Kochanek, Karin, Münzel, Thomas

“…Nitroglycerin (GTN)-induced tolerance was reported to be associated with increased levels of reactive oxygen species (ROS) in mitochondria. In the present…”
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The Oxidative Stress Concept of Nitrate Tolerance and the Antioxidant Properties of Hydralazine by Daiber, Andreas, Mülsch, Alexander, Hink, Ulrich, Mollnau, Hanke, Warnholtz, Ascan, Oelze, Matthias, Münzel, Thomas

“…The hemodynamic and anti-ischemic effects of nitroglycerin (NTG) are rapidly blunted as a result of the development of nitrate tolerance. With initiation of…”
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Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance by Hink, Ulrich, Oelze, Matthias, Kolb, Philip, Bachschmid, Markus, Zou, Ming-Hui, Daiber, Andreas, Mollnau, Hanke, August, Michael, Baldus, Stefan, Tsilimingas, Nikos, Walter, Ulrich, Ullrich, Volker, Münzel, Thomas

“…We tested whether in vivo nitroglycerin (NTG) treatment causes tyrosine nitration of prostacyclin synthase (PGI2-S), one of the nitration targets of…”
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Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: Evidence for an involvement of protein kinase C by Heitzer, Thomas, Wenzel, Ulrich, Hink, Ulrich, Krollner, Dirk, Skatchkov, Mikhail, Stahl, Rolf A.K., Macharzina, Roland, Bräsen, Jan H., Meinertz, Thomas, Münzel, Thomas

“…Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: Evidence for an involvement of protein kinase C. Angiotensin II infusion…”
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Mechanisms of Increased Vascular Superoxide Production in an Experimental Model of Idiopathic Dilated Cardiomyopathy by Mollnau, Hanke, Oelze, Matthias, August, Michael, Wendt, Maria, Daiber, Andreas, Schulz, Eberhard, Baldus, Stephan, Kleschyov, Andrei L, Materne, Anke, Wenzel, Philip, Hink, Ulrich, Nickenig, Georg, Fleming, Ingrid, Münzel, Thomas

“…OBJECTIVE—In the present study, we sought to identify mechanisms underlying increased oxidative stress in vascular tissue in an experimental animal model of…”
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