Search Results - "Hiniesto Iñigo, Irene"
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Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart
Published in International journal of molecular sciences (28-07-2023)“…Long QT syndrome (LQTS) can lead to ventricular arrhythmia and sudden cardiac death. The most common congenital cause of LQTS is mutations in the channel…”
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2
The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species
Published in Channels (Austin, Tex.) (01-12-2024)“…The endogenous endocannabinoid-like compound N-arachidonoyl-L-serine (ARA-S) facilitates activation of the human Kv7.1/KCNE1 channel and shortens a prolonged…”
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3
Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval
Published in EBioMedicine (01-03-2023)“…Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown…”
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4
The endocannabinoid ARA-S displays variably activating effects on Kv7.1/KCNE1 carrying long QT syndrome mutations
Published in Biophysical journal (10-02-2023)Get full text
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5
Cannabidiol differentially modulates Kv7 channelopathy-related phenotypes
Published in Biophysical journal (11-02-2022)Get full text
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6
Human kV7 channel subtypes are differentially modulated by cannabidiol
Published in Biophysical journal (11-02-2022)Get full text
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7
Endocannabinoid-like compounds as modulators of the cardiac kv7.1/KCNE1 channel
Published in Biophysical journal (11-02-2022)Get full text
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8
The endocannabinoid ARA-S displays variably activating effects on K v 7.1/KCNE1 carrying long QT syndrome mutations
Published in Biophysical journal (10-02-2023)Get full text
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Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT intervalResearch in context
Published in EBioMedicine (01-03-2023)“…Background: Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with…”
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10
Endocannabinoids enhance hK V 7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval
Published in EBioMedicine (01-03-2023)“…Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown…”
Get full text
Journal Article