Search Results - "Hingley, Susan T."

Chlamydia pneumoniae : An Etiologic Agent for Late-Onset Dementia by Balin, Brian J, Hammond, Christine J, Little, Christopher Scott, Hingley, Susan T, Al-Atrache, Zein, Appelt, Denah M, Whittum-Hudson, Judith A, Hudson, Alan P

“…The disease known as late-onset Alzheimer's disease is a neurodegenerative condition recognized as the single most commonform of senile dementia. The condition…”
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Endosomal Proteolysis by Cathepsins Is Necessary for Murine Coronavirus Mouse Hepatitis Virus Type 2 Spike-Mediated Entry by ZHAOZHU QIU, HINGLEY, Susan T, SIMMONS, Graham, YU, Christopher, DAS SARMA, Jayasri, BATES, Paul, WEISS, Susan R

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Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease by Al-Atrache, Zein, Lopez, Danielle B, Hingley, Susan T, Appelt, Denah M

“…Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather than…”
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Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus by SHINDLER, Kenneth S, KENYON, Lawrence C, DUTT, Mahasweta, HINGLEY, Susan T, DAS SARMA, Jayasri

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Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus by Kenyon, Lawrence C, Biswas, Kaushiki, Shindler, Kenneth S, Nabar, Manasi, Stout, Marjorie, Hingley, Susan T, Grinspan, Judith B, Das Sarma, Jayasri

“…Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it…”
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Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of [beta]-amyloid found in Alzheimer disease by Al-Atrache, Zein, Lopez, Danielle B, Hingley, Susan T, Appelt, Denah M

“…Background Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather…”
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Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease by Lim, Charles, Hammond, Christine J, Hingley, Susan T, Balin, Brian J

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which infection with Chlamydia pneumoniae (Cpn) has been associated. Cpn is an obligate…”
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Murine Coronavirus Evolution In Vivo: Functional Compensation of a Detrimental Amino Acid Substitution in the Receptor Binding Domain of the Spike Glycoprotein by NAVAS-MARTIN, Sonia, HINGLEY, Susan T, WEISS, Susan R

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Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis by Das Sarma, Jayasri, Kenyon, Lawrence C, Hingley, Susan T, Shindler, Kenneth S

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Recent studies have demonstrated that significant axonal injury also occurs in MS…”
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CELLULAR MODELING OF INFLAMMATION RELEVANT TO ALZHEIMER'S DISEASE: MOLECULAR AND CYTOKINE ANALYSIS OF HOST RESPONSES FOLLOWING CHLAMYDIAL INFECTION OF HUMAN THP-1 MONOCYTES by Hammond, Christine J, Anzmann, Jonathan M, Jain, Abhi P, Hingley, Susan T, Balin, Brian J

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Sequence analysis of the S gene of recombinant MHV-2/A59 coronaviruses reveals three candidate mutations associated with demyelination and hepatitis by Das Sarma, Li Fu, Susan T. Hingley, Michael M. C. Lai, Ehud Lavi, Jayasri

“…Coronaviruses, mouse hepatitis virus (MHV) strains, exhibit various degrees of neurotropism and hepatotropism following intracerebral (IC) infection of…”
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Murine Coronavirus Spike Protein Determines the Ability of the Virus To Replicate in the Liver and Cause Hepatitis by Navas, S, Seo, S H, Chua, M M, Das Sarma, J, Lavi, E, Hingley, S T, Weiss, S R

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Analysis of Chlamydia pneumoniae-infected monocytes following incubation with a novel peptide, acALY18: A potential treatment for infection in Alzheimer's disease by Balin, Brian J, Thacker, James D, Caruthers, Corey M, Hingley, Susan T, Ruszak, Elizabeth K, Zoga, Juliana D, Appelt, Denah M

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P4-059: Induction of amyloid processing in astrocytes and neuronal cells coinfected with herpes simplex virus 1 and Chlamydophila (Chlamydia) pneumoniae : Linkage of an infectious process to Alzheimer's disease by Appelt, Denah M, Triplett, Laura R, Kralik, Kevin S, Ruszak, Elizabeth K, Hingley, Susan T, Balin, Brian J

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Targeted Recombination within the Spike Gene of Murine Coronavirus Mouse Hepatitis Virus-A59: Q159 Is a Determinant of Hepatotropism by Leparc-Goffart, I, Hingley, S T, Chua, M M, Phillips, J, Lavi, E, Weiss, S R

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Mouse Hepatitis Virus Type-2 Infection in Mice: An Experimental Model System of Acute Meningitis and Hepatitis by Sarma, Jayasri Das, Fu, Li, Hingley, Susan T., Lavi, Ehud

“…Infection with mouse hepatitis virus (MHV) strain A59 produces acute hepatitis, encephalitis, and chronic demyelination in mice. However, little is known about…”
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The virulence of mouse hepatitis virus strain A59 is not dependent on efficient spike protein cleavage and cell-to-cell fusion by Hingley, Susan T, Leparc-Goffart, Isabelle, Seo, Su-Hun, Tsai, Jean C, Weiss, Susan R

“…The cleavage and fusion properties of recombinant murine hepatitis viruses (MHV) were examined to assess the role of the cleavage signal in determining the…”
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The Spike Protein of Murine Coronavirus Mouse Hepatitis Virus Strain A59 Is Not Cleaved in Primary Glial Cells and Primary Hepatocytes by Hingley, S T, Leparc-Goffart, I, Weiss, S R

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MHV-A59 fusion mutants are attenuated and display altered hepatotropism by Hingley, S T, Gombold, J L, Lavi, E, Weiss, S R

“…Mouse hepatitis virus strain A59 causes a persistent productive, but nonlytic, infection of cultured glial cells. We have mutants isolated from persistently…”
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Nidoviruses by Hingley, Susan T.

“…Hingley reviews NIDOVIRUSES edited by Stanley Perlman, Thomas Gallagher and Eric J. Snijder…”
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