Search Results - "Hines, Kirk"

Rhodopsin/Lipid Hydrophobic Matching—Rhodopsin Oligomerization and Function by Soubias, Olivier, Teague, Walter E., Hines, Kirk G., Gawrisch, Klaus

“…Lipid composition of the membrane and rhodopsin packing density strongly modulate the early steps of the visual response of photoreceptor membranes. In this…”
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Physiological changes in bilayer thickness induced by cholesterol control GPCR rhodopsin function by Soubias, Olivier, Sodt, Alexander J., Teague, Walter E., Hines, Kirk G., Gawrisch, Klaus

“…We monitored the effect on function of the G-protein-coupled receptor (GPCR) rhodopsin from small, stepwise changes in bilayer thickness induced by…”
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Probing thermostability of detergent-solubilized CB2 receptor by parallel G protein–activation and ligand-binding assays by Beckner, Ryan L., Zoubak, Lioudmila, Hines, Kirk G., Gawrisch, Klaus, Yeliseev, Alexei A.

“…G protein–coupled receptors (GPCRs) comprise a large class of integral membrane proteins involved in the regulation of a broad spectrum of physiological…”
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Determining the structural origin of quantum behaviors in fluorescent proteins by Taumoefolau, Grace H., Puhl, Henry L., Hines, Kirk G., Nguyen, Tuan A., Chen, Eefei, Best, Robert B., Vogel, Steven S.

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Contribution of Membrane Elastic Energy to Rhodopsin Function by Soubias, Olivier, Teague, Walter E., Hines, Kirk G., Mitchell, Drake C., Gawrisch, Klaus

“…We considered the issue of whether shifts in the metarhodopsin I (MI)-metarhodopsin II (MII) equilibrium from lipid composition are fully explicable by…”
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Binary-FRET reveals transient excited-state structure associated with activity-dependent CaMKII - NR2B binding and adaptation by Nguyen, Tuan A., Puhl, Henry L., Hines, Kirk, Liput, Daniel J., Vogel, Steven S.

“…Synaptic functions are mediated and modulated by a coordinated choreography of protein conformational changes and interactions in response to intracellular…”
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The role of membrane curvature elastic stress for function of rhodopsin-like G protein-coupled receptors by Soubias, Olivier, Teague, Walter E., Hines, Kirk G., Gawrisch, Klaus

“…The human genome encodes about 800 different G protein-coupled receptors (GPCR). They are key molecules in signal transduction pathways that transmit signals…”
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Elastic properties of polyunsaturated phosphatidylethanolamines influence rhodopsin function by Teague, Jr, Walter E, Soubias, Olivier, Petrache, Horia, Fuller, Nola, Hines, Kirk G, Rand, R Peter, Gawrisch, Klaus

“…Membranes with a high content of polyunsaturated phosphatidylethanolamines (PE) facilitate formation of metarhodopsin-II (M(II)), the photointermediate of…”
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Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles by Becker-Baldus, Johanna, Yeliseev, Alexei, Joseph, Thomas T., Sigurdsson, Snorri Th, Zoubak, Lioudmila, Hines, Kirk, Iyer, Malliga R., van den Berg, Arjen, Stepnowski, Sam, Zmuda, Jon, Gawrisch, Klaus, Glaubitz, Clemens

“…Tremendous progress has been made in determining the structures of G-protein coupled receptors (GPCR) and their complexes in recent years. However,…”
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The Bacteriorhodopsin Carboxyl-Terminus Contributes to Proton Recruitment and Protein Stability by Turner, George J, Chittiboyina, Shirisha, Pohren, Lauren, Hines, Kirk G, Correia, John J, Mitchell, Drake C

“…We examined functional and structural roles for the bacteriorhodopsin (bR) carboxyl-terminus. The extramembranous and intracellular carboxyl-terminus was…”
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Coherent exciton coupling in fluorescent protein dimers probed by two-photon polarization ratio by Drobizhev, Mikhail, Puhl, Henry L., Hines, Kirk, Vogel, Steven S.

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EPR on site-selective spin-labeled human cannabinoid receptor CB2 by Yeliseev, Alexei, Zoretich, Kaeli, Hooper, Levi, Teague, Walter E., Zoubak, Lioudmila, Hines, Kirk G., Gawrisch, Klaus

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Thermostability of a recombinant G protein-coupled receptor expressed at high level in mammalian cell culture by Yeliseev, Alexei, van den Berg, Arjen, Zoubak, Lioudmila, Hines, Kirk, Stepnowski, Sam, Williston, Kyle, Yan, Wanhua, Gawrisch, Klaus, Zmuda, Jonathan

“…Rational design of pharmaceutical drugs targeting integral membrane G protein-coupled receptors (GPCR) requires thorough understanding of ligand binding and…”
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Selective Chemical Labeling of Type II Cannabinoid Receptor CB2 for 19F-NMR and EPR Studies by Yeliseev, Alexei, Zoubak, Lioudmila, Hines, Kirk G., Teague, Walter E., Gawrisch, Klaus

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Selective Chemical Labeling of Type II Cannabinoid Receptor CB 2 for 19 F-NMR and EPR Studies by Yeliseev, Alexei, Zoubak, Lioudmila, Hines, Kirk G., Teague, Walter E., Gawrisch, Klaus

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G Protein-GPCR Interaction Studied by SANS by Soubias, Olivier, Nickels, Jonathan D., Yeliseev, Alexei, Hines, Kirk G., Teague, Walter E., Northup, John, Katsaras, John, Gawrisch, Klaus

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Controlling GPCR Rhodopsin Function by Small, Physiologically Relevant Changes in Bilayer Hydrophobic Thickness by Soubias, Olivier, Sodt, Alexander J., Teague, Walter E., Hines, Kirk G., Gawrisch, Klaus

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Rhodopsin Dimerization in Membrane Bilayers Revealed by Small Angle Neutron Scattering by Soubias, Olivier, Nickels, Jonathan D., Teague, Walter E., Hines, Kirk G., Weiss, Kevin L., Katsaras, John, Gawrisch, Klaus

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Cannabinoid Receptor CB2 Oligomerization in a Lipid Matrix by Yeliseev, Alexei, Nickels, Jonathan D., Hines, Kirk G., Zoubak, Lioudmila, Teague, Walter E., Lynch, Diane L., Hurst, Dow P., Weiss, Kevin L., Katsaras, John, Reggio, Patricia H., Gawrisch, Klaus

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Rhodopsin Crowding in Model Lipid Bilayers - Functional Implications by Soubias, Olivier, Northup, John K., Hines, Kirk G., Teague, Walter E., Gawrisch, Klaus

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