Search Results - "Hinek, Aleksander"
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Beneficial Effects of Baduanjin Exercise on Left Ventricular Remodelling in Patients after Acute Myocardial Infarction: an Exploratory Clinical Trial and Proteomic Analysis
Published in Cardiovascular drugs and therapy (01-02-2021)“…Background The beneficial effects of physical exercise on cardiac remodelling improvement after myocardial infarction have already been suggested. However, the…”
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Efficacy of Sodium Tanshinone IIA Sulfonate in Patients with Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Results from a Multicentre, Controlled, Randomized Trial
Published in Cardiovascular drugs and therapy (01-04-2021)“…Background Sodium tanshinone IIA sulfonate (STS) has been widely used by Chinese medicine practitioners for chronic cardiovascular diseases. However, its…”
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Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction
Published in Frontiers in pharmacology (12-07-2019)“…The level of maladaptive myocardial remodeling consistently contributes to the poor prognosis of patients following a myocardial infarction (MI). In this…”
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Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA
Published in British journal of cancer (01-02-2019)“…Background Carcinogenesis occurs in elastin-rich tissues and leads to local inflammation and elastolytic proteinase release. This contributes to bioactive…”
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Isolation and characterization of patient-derived CNS metastasis-associated stromal cell lines
Published in Oncogene (01-05-2019)“…The functional role of human derived stromal cells in the tumor microenviornment of CNS metastases (CM) remain understudied. The purpose of the current study…”
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Signaling Pathways Transduced through the Elastin Receptor Facilitate Proliferation of Arterial Smooth Muscle Cells
Published in The Journal of biological chemistry (22-11-2002)“…In this report we demonstrate that soluble peptides, elastin degradation products stimulate proliferation of arterial smooth muscle cells. We show that these…”
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The Antidiabetic Hormone Glucagon-Like Peptide-1 Induces Formation of New Elastic Fibers in Human Cardiac Fibroblasts After Cross-Activation of IGF-IR
Published in Endocrinology (Philadelphia) (01-01-2015)“…Glucagon-like peptide 1 (GLP-1) is a metabolic hormone involved in the stimulation of insulin biosynthesis and secretion. It has been recently reported that…”
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Fat‐1 transgenic mice rich in endogenous omega‐3 fatty acids are protected from lipopolysaccharide‐induced cardiac dysfunction
Published in ESC Heart Failure (01-06-2021)“…Aims Cardiac malfunctions developing in result of sepsis are hard to treat so they eventually contribute to the increased mortality. Previous reports indicated…”
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D115. A Role for Tannic Acid in Restoring Elastogenesis Impaired by Common Aesthetic Agents
Published in Plastic and reconstructive surgery. Global open (01-05-2024)Get full text
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Aldosterone and Mineralocorticoid Receptor Antagonists Modulate Elastin and Collagen Deposition in Human Skin
Published in Journal of investigative dermatology (01-10-2010)“…We have shown that the steroid hormone aldosterone, recognized for its action on the kidney and the cardiovascular system, also modulates deposition of…”
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Modeling and Rescue of the Vascular Phenotype of Williams‐Beuren Syndrome in Patient Induced Pluripotent Stem Cells
Published in Stem cells translational medicine (01-01-2013)“…The objective of this study was to generate a human induced pluripotent stem cell model for in vitro assessment of the Williams‐Beuren syndrome (WBS) phenotype…”
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Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic Fiber Assembly
Published in The Journal of biological chemistry (10-02-2006)“…We have established previously that the 67-kDa elastin-binding protein (EBP), identical to the spliced variant of β-galactosidase, acts as a recyclable…”
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13
Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis
Published in Communications biology (01-02-2023)“…Emerging studies indicate that extracellular vesicles (EVs) and their inner circular RNAs (circRNAs), play key roles in the gene regulatory network and…”
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Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings
Published in PloS one (24-02-2017)“…Vasoactive and mitogenic peptide, endothelin-1 (ET-1) plays an important role in physiology of the ocular tissues by regulating the growth of corneal…”
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Sodium l -ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin
Published in Journal of dermatological science (01-09-2014)“…Highlights • Sodium l-ascorbate (SA) stimulates synthesis new elastin in skin fibroblasts. • This effect of SA occurs only after its active intracellular…”
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Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis
Published in Development (Cambridge) (01-09-2005)“…Glycosaminoglycans (GAGs) such as heparan sulfate and chondroitin sulfate are polysaccharide chains that are attached to core proteins to form proteoglycans…”
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Experimental Right Ventricular Hypertension Induces Regional β1‐Integrin–Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling
Published in Journal of the American Heart Association (29-03-2018)“…Background Development of right ventricular (RV) hypertension eventually contributes to RV and left ventricular (LV) myocardial fibrosis and dysfunction. The…”
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Insulin Induces Production of New Elastin in Cultures of Human Aortic Smooth Muscle Cells
Published in The American journal of pathology (01-02-2012)“…Diabetes mellitus accelerates atherosclerotic progression, peripheral angiopathy development, and arterial hypertension, all of which are associated with…”
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Potential Mechanism of Dermal Wound Treatment With Preparations From the Skin Gel of Arabian Gulf Catfish: A Unique Furan Fatty Acid (F6) and Cholesta-3,5-Diene (S5) Recruit Neutrophils and Fibroblasts to Promote Wound Healing
Published in Frontiers in pharmacology (18-06-2020)“…Preparations from Arabian Gulf c atfish ( Arius bilineatus , Val) epidermal g el secretion (PCEGS) effectively heal chronic wounds in diabetic patients…”
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89. Topical Mineralocorticoid Inhibition Improves Epithelization in Full-thickness Healing Wounds
Published in Plastic and reconstructive surgery. Global open (19-05-2023)Get full text
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