Search Results - "Hinek, A"
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Desialylation of insulin receptors and IGF-1 receptors by neuraminidase-1 controls the net proliferative response of L6 myoblasts to insulin
Published in Glycobiology (Oxford) (01-05-2010)“…We recently established that the subunit of cell surface-residing elastin receptor, neuraminidase-1 (Neu1), can desialylate adjacent insulin-like growth factor…”
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Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes
Published in Neuropathology and applied neurobiology (01-12-2007)“…The extracellular matrix (ECM) plays a critical role during the development and invasion of primary brain tumours. However, the function of ECM components and…”
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Vaccinia Virus Activation of CCR5 Invokes Tyrosine Phosphorylation Signaling Events That Support Virus Replication
Published in Journal of Virology (01-07-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network
Published in British journal of dermatology (1951) (01-11-2010)“…Summary Clinical evaluation of a young woman with subcutaneous fibrotic nodules, progressive distal joint contractures and marfanoid stature revealed a…”
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348 Modeling the Vascular Phenotype of Williams-Beuren Syndrome Using Induced Pluripotent Stem Cells
Published in Canadian journal of cardiology (01-09-2012)Get full text
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67-kD Elastin-Binding Protein Is a Protective "Companion" of Extracellular Insoluble Elastin and Intracellular Tropoelastin
Published in The Journal of cell biology (01-07-1994)“…The 67-kD elastin-binding protein (EBP) mediates cell adhesion to elastin and elastin fiber assembly, and it is similar, if not identical, to the 67-kD…”
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Poxvirus Infection Rapidly Activates Tyrosine Kinase Signal Transduction
Published in The Journal of biological chemistry (21-12-2001)“…Viruses have evolved a number of strategies to gain entry and replicate in host target cells that, for human immunodeficiency virus (HIV) and the poxvirus,…”
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Nature and the multiple functions of the 67-kD elastin-/laminin binding protein
Published in Cell adhesion and communication (01-01-1994)“…Numerous cell types, including fibroblasts, vascular smooth muscle cells, chondroblasts, monocytes, neutrophils, and several tumor cells express the 67-kD…”
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Lysyl oxidase and fibulin_1 interactions in scleroderma
Published in Matrix biology (01-11-2006)Get full text
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The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of β-galactosidase
Published in The Journal of clinical investigation (01-03-1993)“…We and others have previously shown that a 67-kD cell surface elastin/laminin-binding protein (EBP) is responsible for cell adhesion to elastin and laminin and…”
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Loeys-Dietz syndrome (LDS): in vitro studies of skin fibroblasts showing differences between mutations in the TGFBR1 and TGFBR2 genes
Published in Artery research (01-08-2008)Get full text
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UVB Irradiation Stimulates Deposition of New Elastic Fibers by Modified Epithelial Cells Surrounding the Hair Follicles and Sebaceous Glands in Mice
Published in Journal of investigative dermatology (01-04-1999)“…UVB irradiation stimulates the synthesis of elastin in the skin of humans and experimental animals. In this study we localized the site and the cells that are…”
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Journal Article Conference Proceeding -
14
P1.01 Treatment with Dexamethasone Reverses Impared Elastogenesis and Collagenogenesis in Cultures of Fibroblasts from Patients with Loeys-Dietz Syndrome (LDS)
Published in Artery research (2008)“…LDS is an autosomal dominant condition caused by mutations in the TGFBR1 and TGFBR2 genes. The condition is associated with vascular tortuousity and formation…”
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07.04 Loeys-Dietz Syndrome (LDS): In Vitro Studies of Skin Fibroblasts Showing Differences Between Mutations in the TGFBR1 and TGFBR2 Genes
Published in Artery research (2008)“…LDS is a newly described condition caused by mutations in the genes encoding transforming growth factor-beta (TGF-B) receptors 1 and 2. The condition is…”
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The ductus arteriosus migratory smooth muscle cell phenotype processes tropoelastin to a 52-kDa product associated with impaired assembly of elastic laminae
Published in The Journal of biological chemistry (15-01-1993)“…We established the identity of a 52-kDa protein secreted by fetal lamb ductus arteriosus (DA) smooth muscle cells (SMC) and suggest how it might be related to…”
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The Elastin Receptor Shows Structural and Functional Similarities to the 67-kDa Tumor cell Laminin Receptor
Published in The Journal of biological chemistry (05-10-1989)“…Laminin- and elastin-binding proteins were isolated by ligand affinity chromatography from plasma membranes of fetal bovine auricular chondroblasts and human…”
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Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells
Published in Acta neuropathologica (01-04-1999)“…We have recently shown that glioma cell lines, as well as cells of human malignant gliomas in situ, synthesize tropoelastin. In addition, glioma cells degrade…”
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Proteolytic activity of human non-Hodgkin's lymphomas
Published in The American journal of pathology (01-02-1998)“…This study was conducted to assess the net proteolytic activity of human non-Hodgkin's lymphomas (NHLs). We have compared the extracellular matrix…”
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Elastin binds to a multifunctional 67-kilodalton peripheral membrane protein
Published in Biochemistry (Easton) (02-05-1989)“…Elastin binding proteins from plasma membranes of elastin-producing cells were isolated by affinity chromatography on immobilized elastin peptides. Three…”
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