Search Results - "Hindmarsh, Elizabeth J"

Chromatin-Associated Protein Kinase C-θ Regulates an Inducible Gene Expression Program and MicroRNAs in Human T Lymphocytes by Sutcliffe, Elissa L., Bunting, Karen L., He, Yi Qing, Li, Jasmine, Phetsouphanh, Chansavath, Seddiki, Nabila, Zafar, Anjum, Hindmarsh, Elizabeth J., Parish, Christopher R., Kelleher, Anthony D., McInnes, Russell L., Taya, Toshiki, Milburn, Peter J., Rao, Sudha

“…Studies in yeast demonstrate that signaling kinases have a surprisingly active role in the nucleus, where they tether to chromatin and modulate gene expression…”
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Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor by Browne, Cecille D, Hindmarsh, Elizabeth J, Smith, Jeffrey W

“…Orlistat, an antiobesity drug, is cytostatic and cytotoxic to tumor cells (1). The antitumor activity of orlistat can be attributed to its ability to inhibit…”
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Complement Activation Occurs on Subendothelial Extracellular Matrix In Vitro and Is Initiated by Retraction or Removal of Overlying Endothelial Cells by Hindmarsh, Elizabeth J, Marks, Rory M

“…Vascular endothelium is continuously exposed to plasma complement, which could generate a potent proinflammatory signal if activated on the vascular wall…”
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Treatment of central nervous system inflammation with inhibitors of basement membrane degradation by Parish, Christopher R, Hindmarsh, Elizabeth J, Bartlett, Mark R, Staykova, Maria A, Cowden, William B, Willenborg, David O

“…Currently available anti‐inflammatory drugs for the treatment of multiple sclerosis (MS) and other inflammatory diseases are generally inadequate, with disease…”
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Cell surface expression of the 300 kDa mannose-6-phosphate receptor by activated T lymphocytes by Hindmarsh, Elizabeth J, Staykova, Maria A, Willenborg, David O, Parish, Christopher R

“…Phosphosugars, such as mannose‐6‐phosphate (M6P), have been shown previously to display anti‐inflammatory properties, notably inhibition of experimental…”
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Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis by Li, Rachel W., Freeman, Craig, Yu, Di, Hindmarsh, Elizabeth J., Tymms, Kathleen E., Parish, Christopher R., Smith, Paul N.

“…Objective Although heparanase is recognized as a proangiogenic factor, the involvement of heparanase in rheumatoid arthritis (RA) is unclear. In this study, we…”
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5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors by Szabados, Eve, Hindmarsh, Elizabeth J, Phillips, Leonidas, Duggleby, Ronald G, Christopherson, Richard I

“…The bifunctional enzyme 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase-IMP cyclohydrolase has been purified 780-fold to apparent homogeneity…”
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Chromatin-Associated Protein Kinase C-[theta] Regulates an Inducible Gene Expression Program and MicroRNAs in Human T Lymphocytes by Sutcliffe, Elissa L, Bunting, Karen L, He, Yi Qing, Li, Jasmine, Phetsouphanh, Chansavath, Seddiki, Nabila, Zafar, Anjum, Hindmarsh, Elizabeth J, Parish, Christopher R, Kelleher, Anthony D, McInnes, Russell L, Taya, Toshiki, Milburn, Peter J, Rao, Sudha

“…Studies in yeast demonstrate that signaling kinases have a surprisingly active role in the nucleus, where they tether to chromatin and modulate gene expression…”
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Decay‐accelerating factor is a component of subendothelial extracellular matrix in vitro, and is augmented by activation of endothelial protein kinase C by Hindmarsh, Elizabeth J., Marks, Rory M.

“…The vasculature is protected from complement activation by regulatory molecules expressed on endothelial cells. However, complement fixation also occurs on…”
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Decay-accelerating factor is a component of subendothelial extracellular matrixin vitro, and is augmented by activation of endothelial protein kinase C by Hindmarsh, Elizabeth J., Marks, Rory M.

Get full text