Search Results - "Hinderer, Svenja"

Cardiac fibrosis – A short review of causes and therapeutic strategies by Hinderer, Svenja, Schenke-Layland, Katja

“…Fibrotic diseases cause annually more than 800,000 deaths worldwide, whereof the majority accounts for lung and cardiac fibrosis. A pathological remodeling of…”
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ECM and ECM-like materials — Biomaterials for applications in regenerative medicine and cancer therapy by Hinderer, Svenja, Layland, Shannon Lee, Schenke-Layland, Katja

“…Regenerative strategies such as stem cell-based therapies and tissue engineering applications are being developed with the aim to replace, remodel, regenerate…”
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Enhanced elastin synthesis and maturation in human vascular smooth muscle tissue derived from induced-pluripotent stem cells by Eoh, Joon H., Shen, Nian, Burke, Jacqueline A., Hinderer, Svenja, Xia, Zhiyong, Schenke-Layland, Katja, Gerecht, Sharon

“…[Display omitted] Obtaining vascular smooth muscle tissue with mature, functional elastic fibers is a key obstacle in tissue-engineered blood vessels. Poor…”
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Electrospun poly-l-lactide scaffold for the controlled and targeted delivery of a synthetically obtained Diclofenac prodrug to treat actinic keratosis by Piccirillo, Germano, Bochicchio, Brigida, Pepe, Antonietta, Schenke-Layland, Katja, Hinderer, Svenja

“…[Display omitted] Actinic Keratosis’ (AKs) are small skin lesions that are related to a prolonged sun-damage, which can develop into invasive squamous cell…”
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Fibronectin Adsorption on Electrospun Synthetic Vascular Grafts Attracts Endothelial Progenitor Cells and Promotes Endothelialization in Dynamic In Vitro Culture by Daum, Ruben, Visser, Dmitri, Wild, Constanze, Kutuzova, Larysa, Schneider, Maria, Lorenz, Günter, Weiss, Martin, Hinderer, Svenja, Stock, Ulrich A, Seifert, Martina, Schenke-Layland, Katja

“…Appropriate mechanical properties and fast endothelialization of synthetic grafts are key to ensure long-term functionality of implants. We used a newly…”
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Steps toward Maturation of Embryonic Stem Cell-Derived Cardiomyocytes by Defined Physical Signals by Shen, Nian, Knopf, Anne, Westendorf, Claas, Kraushaar, Udo, Riedl, Julia, Bauer, Hannah, Pöschel, Simone, Layland, Shannon Lee, Holeiter, Monika, Knolle, Stefan, Brauchle, Eva, Nsair, Ali, Hinderer, Svenja, Schenke-Layland, Katja

“…Cardiovascular disease remains a leading cause of mortality and morbidity worldwide. Embryonic stem cell-derived cardiomyocytes (ESC-CMs) may offer significant…”
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Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes by Petrigliano, Frank A., Liu, Nancy Q., Lee, Siyoung, Tassey, Jade, Sarkar, Arijita, Lin, Yucheng, Li, Liangliang, Yu, Yifan, Geng, Dawei, Zhang, Jiankang, Shkhyan, Ruzanna, Bogdanov, Jacob, Van Handel, Ben, Ferguson, Gabriel B., Lee, Youngjoo, Hinderer, Svenja, Tseng, Kuo-Chang, Kavanaugh, Aaron, Crump, J. Gage, Pyle, April D., Schenke-Layland, Katja, Billi, Fabrizio, Wang, Liming, Lieberman, Jay, Hurtig, Mark, Evseenko, Denis

“…Osteoarthritis (OA) impacts hundreds of millions of people worldwide, with those affected incurring significant physical and financial burdens. Injuries such…”
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Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine by Hinderer, Svenja, Brauchle, Eva, Schenke-Layland, Katja

“…Current clinically applicable tissue and organ replacement therapies are limited in the field of cardiovascular regenerative medicine. The available options do…”
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Engineering of a bio-functionalized hybrid off-the-shelf heart valve by Hinderer, Svenja, Seifert, Jan, Votteler, Miriam, Shen, Nian, Rheinlaender, Johannes, Schäffer, Tilman E, Schenke-Layland, Katja

“…Abstract Currently available heart valve replacements are limited in long-term performance or fail due to leaflet thickening, lack of growth or remodeling…”
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Skin tissue engineering — In vivo and in vitro applications by Groeber, Florian, Holeiter, Monika, Hampel, Martina, Hinderer, Svenja, Schenke-Layland, Katja

“…Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for…”
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Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells by Hinderer, Svenja, Sudrow, Katrin, Schneider, Maria, Holeiter, Monika, Layland, Shannon Lee, Seifert, Martina, Schenke-Layland, Katja

“…Decorin (DCN) is an important small leucine-rich proteoglycan present in the extracellular matrix (ECM) of many organs and tissues. Endothelial progenitor…”
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An injectable alginate/extra cellular matrix (ECM) hydrogel towards acellular treatment of heart failure by Curley, Clive J., Dolan, Eimear B., Otten, Matthias, Hinderer, Svenja, Duffy, Garry P., Murphy, Bruce P.

“…As treatments for myocardial infarction (MI) continue to improve, the population of people suffering from heart failure (HF) is rising significantly. Novel…”
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Engineering of fibrillar decorin matrices for a tissue-engineered trachea by Hinderer, Svenja, Schesny, Marianne, Bayrak, Alexandra, Ibold, Bettina, Hampel, Martina, Walles, Thorsten, Stock, Ulrich A, Seifert, Martina, Schenke-Layland, Katja

“…Abstract Decorin is a structural and functional proteoglycan (PG) residing in the complex network of extracellular matrix (ECM) proteins in many connective…”
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Cold atmospheric plasma for potential in vivo applications: Raman microsprectrometry determined effects on cervical cancer cells by Weiss, Martin, Daum, Ruben, Hinderer, Svenja, Brauchle, Eva, Wallwiener, Diethelm, Brucker, Sara, Schenke-Layland, Katja

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Preserved bioactivity and tunable release of a SDF1-GPVI bi-specific protein using photo-crosslinked PEGda hydrogels by Schesny, Marianne K, Monaghan, Michael, Bindermann, Andrea H, Freund, Désirée, Seifert, Martina, Eble, Johannes A, Vogel, Sebastian, Gawaz, Meinrad P, Hinderer, Svenja, Schenke-Layland, Katja

“…Abstract Chemokine-induced stem cell recruitment is a promising strategy for post myocardial infarction treatment. Injection of stromal cell-derived factor 1…”
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Hyaluronic Acid-Functionalized Hybrid Gelatin-Poly-L-Lactide Scaffolds with Tunable Hydrophilicity by Piccirillo, Germano, Feuerer, Nora, Carvajal Berrio, Daniel A, Layland, Shannon L, Reimer Hinderer, Svenja, Bochicchio, Brigida, Schenke-Layland, Katja

“…In this study, we describe the production of hybrid gelatin-poly-L-lactide electrospun scaffolds whose hydrophilicity was controlled by binding increasing…”
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Skin Tissue Engineering—In Vivo and In Vitro Applications by Groeber, Florian, Holeiter, Monika, Hampel, Martina, Hinderer, Svenja, Schenke-Layland, Katja

“…Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for…”
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Macrophage retrieval from 3D biomaterials: A detailed comparison of common dissociation methods by Feuerer, Nora, Morschl, Johannes, Daum, Ruben, Weiss, Martin, Hinderer, Svenja, Schenke-Layland, Katja, Shipp, Christopher

“…The immune system is widely recognized as a crucial determinant in implant biocompatibility and tissue integration. In order to assess macrophage response to…”
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In vitro elastogenesis: instructing human vascular smooth muscle cells to generate an elastic fiber-containing extracellular matrix scaffold by Hinderer, Svenja, Shena, Nian, Ringuette, Léa-Jeanne, Hansmann, Jan, Reinhardt, Dieter P, Brucker, Sara Y, Davis, Elaine C, Schenke-Layland, Katja

“…Elastic fibers are essential for the proper function of organs including cardiovascular tissues such as heart valves and blood vessels. Although (tropo)elastin…”
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In vitro elastogenesis (87.1) by Hinderer, Svenja, Shen, Nian, Ringuette, Léa‐Jeanne, Hansmann, Jan, Reinhardt, Dieter, Elaine, Davis, Schenke‐Layland, Katja

“…Background: Elastic fibers are one of the main components of the extracellular matrix (ECM), providing dynamic tissues such as lungs, skin, blood vessels,…”
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