Search Results - "Hind Hamzeh-Cognasse"

Platelet‐derived extracellular vesicles convey mitochondrial DAMPs in platelet concentrates and their levels are associated with adverse reactions by Marcoux, Genevieve, Magron, Audrey, Sut, Caroline, Laroche, Audree, Laradi, Sandrine, Hamzeh‐Cognasse, Hind, Allaeys, Isabelle, Cabon, Ophelie, Julien, Anne‐Sophie, Garraud, Olivier, Cognasse, Fabrice, Boilard, Eric

“…BACKGROUND Whereas platelet transfusion is a common medical procedure, inflammation still occurs in a fraction of transfused individuals despite the absence of…”
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Quality assessment of red blood cell concentrates from blood donors at the extremes of the age spectrum: The BEST collaborative study by Cloutier, Marc, Cognasse, Fabrice, Yokoyama, Ana Paula Hitomi, Hazegh, Kelsey, Mykhailova, Olga, Brandon‐Coatham, Mackenzie, Hamzeh‐Cognasse, Hind, Kutner, Jose Mauro, Acker, Jason P., Kanias, Tamir

“…Background Blood donors at the extremes of the age spectrum (16–19 years vs. ≥75 years) are characterized by increased risks of iron deficiency and anemia, and…”
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DAMPS and complement activation in platelet concentrates that induce adverse reactions in patients by Wit, Yasmin E. S., Hamzeh‐Cognasse, Hind, Cognasse, Fabrice, Brinke, Anja, Zeerleder, Sacha S.

“…Background Patients with severe thrombocytopenia due to bone marrow failure and after chemotherapy are still treated with platelet transfusions. Platelet…”
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Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study by Cognasse, Fabrice, Hamzeh Cognasse, Hind, Eyraud, Marie Ange, Prier, Amélie, Arthaud, Charles Antoine, Tiberghien, Pierre, Begue, Stephane, Korte, Dirk, Gouwerok, Eric, Greinacher, Andreas, Aurich, Konstanze, Noorman, Femke, Dumont, Larry, Kelly, Kathleen, Cloutier, Marc, Bazin, Renée, Cardigan, Rebecca, Huish, Sian, Smethurst, Peter, Devine, Dana, Schubert, Peter, Johnson, Lacey, Marks, Denese C.

“…Background Structural and biochemical changes in stored platelets are influenced by collection and processing methods. This international study investigates…”
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Platelet depletion limits the severity but does not prevent the occurrence of experimental transfusion‐related acute lung injury by Cognasse, Fabrice, Tariket, Sofiane, Hamzeh‐Cognasse, Hind, Arthaud, Charles‐Antoine, Eyraud, Marie‐Ange, Bourlet, Thomas, Berthelot, Philippe, Laradi, Sandrine, Fauteux‐Daniel, Sebastien, Garraud, Olivier

“…BACKGROUND Transfusion‐related acute lung injury (TRALI) is a severe pulmonary reaction due to blood transfusions. The pathophysiology of this complication is…”
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Inhibition of the CD40/CD40L complex protects mice against ALI‐induced pancreas degradation by Tariket, Sofiane, Hamzeh‐Cognasse, Hind, Arthaud, Charles‐Antoine, Laradi, Sandrine, Bourlet, Thomas, Berthelot, Philippe, Garraud, Olivier, Cognasse, Fabrice

“…BACKGROUND Acute lung injury (ALI) is a severe complication of transfusion. In a previous study, we saw that inhibition of the CD40/CD40L complex allowed…”
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Soluble CD40L and CD62P levels differ in single‐donor apheresis platelet concentrates and buffy coat–derived pooled platelet concentrates by Sut, Caroline, Tariket, Sofiane, Aloui, Chaker, Arthaud, Charles‐Antoine, Eyraud, Marie‐Ange, Fagan, Jocelyne, Chavarin, Patricia, Hamzeh‐Cognasse, Hind, Laradi, Sandrine, Garraud, Olivier, Cognasse, Fabrice

“…BACKGROUND Platelet storage lesions are structural and biochemical changes in platelet concentrates (PCs), and depend on variables in collection and…”
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Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets by Cognasse, Fabrice, Hamzeh‐Cognasse, Hind, Lafarge, Sandrine, Delezay, Olivier, Pozzetto, Bruno, McNicol, Archie, Garraud, Olivier

“…Summary Blood platelets link the processes of haemostasis and inflammation. This study examined the immunomodulatory factors released by platelets after…”
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Platelet concentrate supernatants alter endothelial cell mRNA and protein expression patterns as a function of storage length by Sut, Caroline, Hamzeh‐Cognasse, Hind, Arthaud, Charles‐Antoine, Eyraud, Marie‐Ange, Chettab, Kamel, Dumontet, Charles, Laradi, Sandrine, Burnouf, Thierry, Garraud, Olivier, Cognasse, Fabrice

“…BACKGROUND Platelet transfusions are safe but can nevertheless cause serious adverse reactions (SARs). This study investigated the effects of platelet…”
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Properties of donated red blood cell components from patients with hereditary hemochromatosis by Sut, Caroline, Hamzeh‐Cognasse, Hind, Laradi, Sandrine, Bost, Vincent, Aubrège, Christine, Acquart, Sophie, Vignal, Martine, Boutahar, Nadia, Arthaud, Charles Antoine, Ange Eyraud, Marie, Pozzetto, Bruno, Tiberghien, Pierre, Garraud, Olivier, Cognasse, Fabrice

“…BACKGROUND Red blood cells (RBCs) contain large amounts of iron, and periodic therapeutic phlebotomy is thus the main treatment for hereditary hemochromatosis…”
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Revisiting Platelets and Toll-Like Receptors (TLRs): At the Interface of Vascular Immunity and Thrombosis by Hally, Kathryn, Fauteux-Daniel, Sebastien, Hamzeh-Cognasse, Hind, Larsen, Peter, Cognasse, Fabrice

“…While platelet function has traditionally been described in the context of maintaining vascular integrity, recent evidence suggests that platelets can modulate…”
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Platelet Innate Immune Receptors and TLRs: A Double-Edged Sword by Ebermeyer, Théo, Cognasse, Fabrice, Berthelot, Philippe, Mismetti, Patrick, Garraud, Olivier, Hamzeh-Cognasse, Hind

“…Platelets are hematopoietic cells whose main function has for a long time been considered to be the maintenance of vascular integrity. They have an essential…”
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Platelet Inflammatory Response to Stress by Cognasse, Fabrice, Laradi, Sandrine, Berthelot, Philippe, Bourlet, Thomas, Marotte, Hubert, Mismetti, Patrick, Garraud, Olivier, Hamzeh-Cognasse, Hind

“…Blood platelets play a central hemostatic role, (i) as they repair vascular epithelial damage, and (ii) they play immune defense roles, as they have the…”
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Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation by Boudreau, Luc H., Duchez, Anne-Claire, Cloutier, Nathalie, Soulet, Denis, Martin, Nicolas, Bollinger, James, Paré, Alexandre, Rousseau, Matthieu, Naika, Gajendra S., Lévesque, Tania, Laflamme, Cynthia, Marcoux, Geneviève, Lambeau, Gérard, Farndale, Richard W., Pouliot, Marc, Hamzeh-Cognasse, Hind, Cognasse, Fabrice, Garraud, Olivier, Nigrovic, Peter A., Guderley, Helga, Lacroix, Steve, Thibault, Louis, Semple, John W., Gelb, Michael H., Boilard, Eric

“…Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found outside the cells in blood in various pathologies. Platelets are…”
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Platelets as Key Factors in Inflammation: Focus on CD40L/CD40 by Cognasse, Fabrice, Duchez, Anne Claire, Audoux, Estelle, Ebermeyer, Theo, Arthaud, Charles Antoine, Prier, Amelie, Eyraud, Marie Ange, Mismetti, Patrick, Garraud, Olivier, Bertoletti, Laurent, Hamzeh-Cognasse, Hind

“…Platelets are anucleate cytoplasmic fragments derived from the fragmentation of medullary megakaryocytes. Activated platelets adhere to the damaged endothelium…”
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Immunothrombosis and the Role of Platelets in Venous Thromboembolic Diseases by Heestermans, Marco, Poenou, Géraldine, Duchez, Anne-Claire, Hamzeh-Cognasse, Hind, Bertoletti, Laurent, Cognasse, Fabrice

“…Venous thromboembolism (VTE) is the third leading cardiovascular cause of death and is conventionally treated with anticoagulants that directly antagonize…”
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Platelet-derived sCD40L: specific inflammatory marker for early-stage severe acute respiratory syndrome coronavirus 2 infection by Hamzeh-Cognasse, Hind, Mansour, Alexandre, Reizine, Florian, Mismetti, Patrick, Gouin-Thibault, Isabelle, Cognasse, Fabrice

“…The SARS-CoV-2 virus is the causing agent of the Coronavirus disease 2019 (COVID-19) characterized by a huge pro-inflammatory response and coagulation…”
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Key topographic parameters driving surface adhesion of Porphyromonas gingivalis by Papa, Steve, Maalouf, Mathieu, Claudel, Pierre, Sedao, Xxx, Di Maio, Yoan, Hamzeh-Cognasse, Hind, Thomas, Mireille, Guignandon, Alain, Dumas, Virginie

“…Dental implant failure is primarily due to peri-implantitis, a consequence of bacterial biofilm formation. Bacterial adhesion is strongly linked to…”
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The signaling role of CD40 ligand in platelet biology and in platelet component transfusion by Aloui, Chaker, Prigent, Antoine, Sut, Caroline, Tariket, Sofiane, Hamzeh-Cognasse, Hind, Pozzetto, Bruno, Richard, Yolande, Cognasse, Fabrice, Laradi, Sandrine, Garraud, Olivier

“…The CD40 ligand (CD40L) is a transmembrane molecule of crucial interest in cell signaling in innate and adaptive immunity. It is expressed by a variety of…”
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Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications by Heestermans, Marco, Poenou, Géraldine, Hamzeh-Cognasse, Hind, Cognasse, Fabrice, Bertoletti, Laurent

“…Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent) venous thromboembolism (VTE). Drugs to prevent clotting have been used…”
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