Search Results - "Hinchliffe, Matthew"
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TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life
Published in mAbs (2023)“…TrYbe® is an Fc-free therapeutic antibody format, capable of engaging up to three targets simultaneously, with long half-life conferred by albumin binding…”
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Chinese hamster ovary cell line engineering strategies for modular production of custom extracellular vesicles
Published in Biotechnology and bioengineering (01-09-2024)“…Continuously secreted by all cell types, extracellular vesicles (EVs) are small membrane‐bound structures which shuttle bioactive cargo between cells across…”
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GFP‐tagging of extracellular vesicles for rapid process development
Published in Biotechnology journal (01-06-2022)“…Extracellular vesicles (EVs) act as nano‐scale molecular messengers owing to their capacity to shuttle functional macromolecular cargo between cells. This…”
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A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cells
Published in Biotechnology and bioengineering (01-12-2021)“…Monoclonal antibodies are the leading class of biopharmaceuticals in terms of numbers approved for therapeutic purposes. Antigen‐binding fragments (Fab) are…”
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From Clone Selection to 80L Bioreactor Production: Better, Faster, Leaner
Published in BMC proceedings (14-12-2015)“…Bio-pharmaceutical industries face an increasing demand to accelerate process development and reduce costs. Indeed as technologies mature, pressure on cost and…”
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TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life
Published in mAbs (31-12-2023)“…TrYbe® is an Fc-free therapeutic antibody format, capable of engaging up to three targets simultaneously, with long in vivo half-life conferred by albumin…”
Get full text
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Origin Of Typhoid Fever
Published in British medical journal (15-05-1875)Get full text
Journal Article