Search Results - "Himonas, Ekaterini"

Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia by de Beauchamp, Lucie, Himonas, Ekaterini, Helgason, G. Vignir

“…While the understanding of the genomic aberrations that underpin chronic and acute myeloid leukaemia (CML and AML) has allowed the development of therapies for…”
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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche by Dawson, Amy, Zarou, Martha M., Prasad, Bodhayan, Bittencourt-Silvestre, Joana, Zerbst, Désirée, Himonas, Ekaterini, Hsieh, Ya-Ching, van Loon, Isabel, Blanco, Giovanny Rodriguez, Ianniciello, Angela, Kerekes, Zsombor, Krishnan, Vaidehi, Agarwal, Puneet, Almasoudi, Hassan, McCluskey, Laura, Hopcroft, Lisa E. M., Scott, Mary T., Baquero, Pablo, Dunn, Karen, Vetrie, David, Copland, Mhairi, Bhatia, Ravi, Coffelt, Seth B., Tiong, Ong Sin, Wheadon, Helen, Zanivan, Sara, Kirschner, Kristina, Helgason, G. Vignir

“…Macrophages are fundamental cells of the innate immune system that support normal haematopoiesis and play roles in both anti-cancer immunity and tumour…”
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Nutrient-Sensitising Drug Repurposing Screen Identifies Lomerizine As a Mitochondrial Metabolism Inhibitor in Chronic Myeloid Leukaemia by Khalaf, Ahmed, Beauchamp, Lucie de, Kalkman, Eric, Rattigan, Kevin, Himonas, Ekaterini, Jones, Joe, James, Daniel, Shokry, Engy Shokry Abd, Scott, Mary, Dunn, Karen, Tardito, Saverio, Copland, Mhairi, Sumpton, David, Shanks, Emma, Helgason, Vignir

“…In chronic myeloid leukaemia (CML), the persistence of leukaemic stem cells (LSCs) following first line treatment with tyrosine kinase inhibitors (TKIs) such…”
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Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia by Khalaf, Ahmed, de Beauchamp, Lucie, Kalkman, Eric, Rattigan, Kevin, Himonas, Ekaterini, Jones, Joe, James, Daniel, Shokry, Engy Shokry Abd, Scott, Mary T, Dunn, Karen, Tardito, Saverio, Copland, Mhairi, Sumpton, David, Shanks, Emma, Helgason, G Vignir

“…In chronic myeloid leukemia (CML), the persistence of leukemic stem cells (LSCs) after treatment with tyrosine kinase inhibitors (TKIs), such as imatinib, can…”
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