Search Results - "Hilty, Matthias P."
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ECCO2R therapy in the ICU: consensus of a European round table meeting
Published in Critical care (London, England) (07-08-2020)“…Abstract Background With recent advances in technology, patients with acute respiratory distress syndrome (ARDS) and severe acute exacerbations of chronic…”
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Tissue oxygenation: how to measure, how much to target
Published in Intensive care medicine experimental (23-09-2023)Get full text
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3
Bacterial pulmonary superinfections are associated with longer duration of ventilation in critically ill COVID-19 patients
Published in Cell reports. Medicine (20-04-2021)“…The impact of secondary bacterial infections (superinfections) in coronavirus disease 2019 (COVID-19) is not well understood. In this prospective, monocentric…”
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The physiological basis for individualized oxygenation targets in critically ill patients with circulatory shock
Published in Intensive care medicine experimental (22-08-2024)“…Background Circulatory shock, defined as decreased tissue perfusion, leading to inadequate oxygen delivery to meet cellular metabolic demands, remains a common…”
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Nitroglycerin challenge identifies microcirculatory target for improved resuscitation in patients with circulatory shock
Published in Intensive care medicine experimental (02-09-2024)“…Background Circulatory shock and multi-organ failure remain major contributors to morbidity and mortality in critically ill patients and are associated with…”
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A Single 60.000 IU Dose of Erythropoietin Does Not Improve Short-Term Aerobic Exercise Performance in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial
Published in Frontiers in physiology (29-09-2020)“…Erythropoietin (EPO) boosts exercise performance through increase in oxygen transport capacity following regular administration of EPO but preclinical study…”
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Critical care staffing ratio and outcome of COVID-19 patients requiring intensive care unit admission during the first pandemic wave: a retrospective analysis across Switzerland from the RISC-19-ICU observational cohort
Published in Swiss medical weekly (20-06-2022)“…STUDY AIM: The surge of admissions due to severe COVID-19 increased the patients-to-critical care staffing ratio within the ICUs. We investigated whether the…”
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The SARS-CoV-2 Pandemic Impacts the Management of Swiss Pediatric Intensive Care Units
Published in Frontiers in pediatrics (28-01-2022)“…The impact of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic on pediatric intensive care units (PICUs) is difficult to quantify. We…”
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Association between serosal intestinal microcirculation and blood pressure during major abdominal surgery
Published in Journal of intensive medicine (01-07-2021)“…In clinical practice, blood pressure is used as a resuscitation goal on a daily basis, with the aim of maintaining adequate perfusion and oxygen delivery to…”
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Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients
Published in Perioperative medicine (London) (09-08-2018)“…Management of tissue perfusion following cardiac surgery is a challenging task where common clinical parameters do not reflect microcirculatory dysfunction…”
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Artificial intelligence in intensive care: moving towards clinical decision support systems
Published in Minerva anestesiologica (01-12-2022)Get full text
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How to Synchronize Longitudinal Patient Data With the Underlying Disease Progression: A Pilot Study Using the Biomarker CRP for Timing COVID-19
Published in Frontiers in medicine (08-07-2021)“…The continued digitalization of medicine has led to an increased availability of longitudinal patient data that allows the investigation of novel and known…”
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Automated quantification of tissue red blood cell perfusion as a new resuscitation target
Published in Current opinion in critical care (01-06-2020)“…Identification of insufficient tissue perfusion is fundamental to recognizing circulatory shock in critically ill patients, and the primary target to restore…”
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14
A microcirculation-guided trial doomed to fail
Published in Intensive care medicine (01-12-2023)Get full text
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15
To compare the incomparable: COVID-19 pneumonia and high-altitude disease
Published in The European respiratory journal (01-06-2020)“…The coronavirus disease 2019 (COVID-19) pandemic is overwhelming healthcare systems worldwide. There is no evidence from randomised clinical trials that any…”
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16
Mind the Gap - From Big Data to Physiology (and Back)
Published in Respiratory care (01-04-2021)Get full text
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Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock
Published in Anesthesiology (Philadelphia) (01-11-2019)“…BACKGROUND:Primary resuscitation fluid to treat hemorrhagic shock remains controversial. Use of hydroxyethyl starches raised concerns of acute kidney injury…”
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Capillary Leukocytes, Microaggregates, and the Response to Hypoxemia in the Microcirculation of Coronavirus Disease 2019 Patients
Published in Critical care medicine (01-04-2021)“…In this study, we hypothesized that coronavirus disease 2019 patients exhibit sublingual microcirculatory alterations caused by inflammation, coagulopathy, and…”
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Heat training increases exercise capacity in hot but not in temperate conditions: a mechanistic counter-balanced cross-over study
Published in American journal of physiology. Heart and circulatory physiology (01-09-2015)“…The aim was to determine the mechanisms facilitating exercise performance in hot conditions following heat training. In a counter-balanced order, seven males…”
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Increased protocol adherence and safety during controlled normothermia as compared to hypothermia after cardiac arrest
Published in Journal of critical care (01-06-2021)“…This study aims to compare protocol adherence, neurological outcome and adverse effects associated with a controlled hypothermia versus a controlled…”
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