Minimum information about a protein affinity reagent (MIAPAR)

This is a proposal developed within the community as an important first step in formalizing standards in reporting the production and properties of protein binding reagents, such as antibodies, developed and sold for the identification and detection of specific proteins present in biological samples...

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Bibliographic Details
Published in:	Nature biotechnology Vol. 28; no. 7; pp. 650 - 653
Main Authors:	Orchard, Sandra, Bourbeillon, Julie, Benhar, Itai, Borrebaeck, Carl, de Daruvar, Antoine, Dübel, Stefan, Frank, Ronald, Gibson, Frank, Gloriam, David, Haslam, Niall, Hiltker, Tara, Humphrey-Smith, Ian, Hust, Michael, Juncker, David, Koegl, Manfred, Konthur, Zoltàn, Korn, Bernhard, Krobitsch, Sylvia, Muyldermans, Serge, Nygren, Per-Åke, Palcy, Sandrine, Polic, Bojan, Rodriguez, Henry, Sawyer, Alan, Schlapshy, Martin, Snyder, Michael, Stoevesandt, Oda, Taussig, Michael J, Templin, Markus, Uhlen, Matthias, van der Maarel, Silvere, Wingren, Christer, Hermjakob, Henning, Sherman, David
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01-07-2010 Nature Publishing Group
Subjects:	631/1647/2196 Affinity Labels Agriculture Basic Medicine Biochemistry Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Chemical tests and reagents Computer Science correspondence Immunologi inom det medicinska området Immunology in the medical area Indicators and Reagents - chemistry Life Sciences Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Methods Product development Properties Proteins - chemistry Proteomics Quantitative Methods Germany
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Summary:	This is a proposal developed within the community as an important first step in formalizing standards in reporting the production and properties of protein binding reagents, such as antibodies, developed and sold for the identification and detection of specific proteins present in biological samples. It defines a checklist of required information, intended for use by producers of affinity reagents, quality-control laboratories, users and databases. We envision that both commercial and freely available affinity reagents, as well as published studies using these reagents, could include a MIAPAR-compliant document describing the product's properties with every available binding partner.
Bibliography:	SourceType-Other Sources-1 ObjectType-Article-2 content type line 63 ObjectType-Correspondence-1 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	1087-0156 1546-1696 1546-1696
DOI:	10.1038/nbt0710-650