Search Results - "Hilscherová, K."

Identification of new endocrine disruptive transthyretin ligands in polluted waters using pull-down assay coupled to non-target mass spectrometry by Mikušová, P., Toušová, Z., Sehnal, L., Kuta, J., Grabicová, K., Fedorova, G., Marek, M., Grabic, R., Hilscherová, K.

“…Surface and treated wastewater are contaminated with highly complex mixtures of micropollutants, which may cause numerous adverse effects, often mediated by…”
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Retinoid-like compounds produced by phytoplankton affect embryonic development of Xenopus laevis by Smutná, M., Priebojová, J., Večerková, J., Hilscherová, K.

“…Teratogenic effects, which were remarkably similar to those induced by retinoic acids, have been seen in wild frogs indicating possible source of retinoids in…”
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Cyanobacterial harmful bloom lipopolysaccharides: pro-inflammatory effects on epithelial and immune cells in vitro by Skočková, V., Raptová, P., Pospíchalová, K., Sovadinová, I., Sychrová, E., Smutná, M., Hilscherová, K., Babica, P., Šindlerová, L.

“…Cyanobacterial harmful blooms (CyanoHABs) pose a global ecological problem, and their lipopolysaccharides (LPS) are among the bioactive compounds they release…”
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Impact of acute and subchronic inhalation exposure to PbO nanoparticles on mice by Lebedová, J, Nováková, Z, Večeřa, Z, Buchtová, M, Dumková, J, Dočekal, B, Bláhová, L, Mikuška, P, Míšek, I, Hampl, A, Hilscherová, K

“…Lead nanoparticles (NPs) are released into air from metal processing, road transport or combustion processes. Inhalation exposure is therefore very likely to…”
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Environmental xenobiotics and nuclear receptors—Interactions, effects and in vitro assessment by Janošek, J., Hilscherová, K., Bláha, L., Holoubek, I.

“…A group of intracellular nuclear receptors is a protein superfamily including arylhydrocarbon AhR, estrogen ER, androgen AR, thyroid TR and retinoid receptors…”
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In vitro modulation of intracellular receptor signaling and cytotoxicity induced by extracts of cyanobacteria, complex water blooms and their fractions by Štěpánková, T., Ambrožová, L., Bláha, L., Giesy, J.P., Hilscherová, K.

“…► The study was carried out to investigate if cyanobacteria can affect signaling pathways. ► Such toxic potencies were determined mainly by reporter gene…”
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AhR-mediated and antiestrogenic activity of humic substances by Janošek, J., Bittner, M., Hilscherová, K., Bláha, L., Giesy, J.P., Holoubek, I.

“…Humic substances (HS) were for decades regarded as inert in the ecosystems with respect to their possible toxicity. However, HS have been recently shown to…”
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Dioxin-Like and Endocrine Disruptive Activity of Traffic-Contaminated Soil Samples by Šídlová, T., Novák, J., Janošek, J., Anděl, P., Giesy, J. P., Hilscherová, K.

“…Pollution of surface soils by traffic, especially along major highways, can be a significant issue. Numerous studies have demonstrated traffic to be an…”
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Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna by FELDMANNOVA, M, HILSCHEROVA, K, MARSALEK, B, BLAHA, L

“…N‐heterocyclic polycyclic aromatic hydrocarbons (N‐PAHs) belong among newly identified classes of environmental pollutants with relatively high toxic…”
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Changes of AhR-mediated activity of humic substances after irradiation by Bittner, M., Hilscherová, K., Giesy, J.P.

“…Humic substances (HS) and natural organic matter (NOM) are natural organic compounds ubiquitous in the environment. However, some studies indicate that both HS…”
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Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters by Jálová, V., Jarošová, B., Bláha, L., Giesy, J.P., Ocelka, T., Grabic, R., Jurčíková, J., Vrana, B., Hilscherová, K.

“…Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to…”
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Estrogenic activity in extracts and exudates of cyanobacteria and green algae by Sychrová, E., Štěpánková, T., Nováková, K., Bláha, L., Giesy, J.P., Hilscherová, K.

“…Here is presented some of the first information on interactions of compounds produced by cyanobacteria and green algae with estrogen receptor signaling…”
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Simultaneous determination of reduced and oxidized glutathione in tissues by a novel liquid chromatography-mass spectrometry method: application in an inhalation study of Cd nanoparticles by Bláhová, L., Kohoutek, J., Lebedová, J., Bláha, L., Večeřa, Z., Buchtová, M., Míšek, I., Hilscherová, K.

“…The paper presents the development of an advanced extraction and fast analytical LC MS/MS method for simultaneous analyses of reduced and oxidized glutathione…”
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Impact of acute and chronic inhalation exposure to CdO nanoparticles on mice by Lebedová, J., Bláhová, L., Večeřa, Z., Mikuška, P., Dočekal, B., Buchtová, M., Míšek, I., Dumková, J., Hampl, A., Hilscherová, K.

“…Cadmium nanoparticles can represent a risk in both industrial and environmental settings, but there is little knowledge on the impacts of their inhalation,…”
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Estrogenic activity and contributing compounds in stagnant water bodies with massive occurrence of phytoplankton by Prochazkova, T., Sychrova, E., Vecerkova, J., Javurkova, B., Otoupalikova, A., Pernica, M., Simek, Z., Smutna, M., Lepsova-Skacelova, O., Hilscherova, K.

“…Stagnant water bodies have generally received little attention regarding the presence of endocrine disruptive compounds, although they can integrate diverse…”
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Retinoid compounds associated with water blooms dominated by Microcystis species by Javůrek, J., Sychrová, E., Smutná, M., Bittner, M., Kohoutek, J., Adamovský, O., Nováková, K., Smetanová, S., Hilscherová, K.

“…•Retinoid-like activity and retinoic acids found in water and cyanobacteria from lakes.•Studied independent water bodies with bloom dominated by Microcystis…”
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Endocrine disruption of thyroid hormone system - in vitro assessment of several modes of action of chemicals and environmental samples by Kumari, P., Liu, R., Smutná, M., Novák, J., Hilscherová, K

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P09-26: Methods for the assessment of deiodinases inhibition by thyroid hormone disrupting chemicals and environmental pollutant mixtures by Ryšavá, T., Janečková, V., Brózman, O., Hřibová, S., Novák, J., Hilscherová, K.

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Effects of Different Oxygen Saturation on Activity of Complex Biomass and Aqueous Crude Extract of Cyanobacteria During Embryonal Development in Carp (Cyprinus carpio L.) by Palíková, M., Krejčí, R., Hilscherová, K., Burýšková, B., Babica, P., Navrátil, S., Kopp, R., Bláha, L.

“…This study evaluates the effects of different oxygen concentrations on the toxicity of complex cyanobacterial biomass and aqueous extract of two cyanobacterial…”
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Assessment of the Effects of Chemicals on the Expression of Ten Steroidogenic Genes in the H295R Cell Line Using Real-Time PCR by Hilscherova, Klara, Jones, Paul D., Gracia, Tannia, Newsted, John L., Zhang, Xiaowei, Sanderson, J. T., Yu, Richard M. K., Wu, Rudolf S. S., Giesy, John P.

“…The potential for a variety of environmental contaminants to disturb endocrine function in wildlife and humans has been of recent concern. While much effort is…”
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