Search Results - "Hilmer, K"

Demonstration of Protein-Based Human Identification Using the Hair Shaft Proteome by Parker, Glendon J, Leppert, Tami, Anex, Deon S, Hilmer, Jonathan K, Matsunami, Nori, Baird, Lisa, Stevens, Jeffery, Parsawar, Krishna, Durbin-Johnson, Blythe P, Rocke, David M, Nelson, Chad, Fairbanks, Daniel J, Wilson, Andrew S, Rice, Robert H, Woodward, Scott R, Bothner, Brian, Hart, Bradley R, Leppert, Mark

“…Human identification from biological material is largely dependent on the ability to characterize genetic polymorphisms in DNA. Unfortunately, DNA can degrade…”
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Inhibition of early response genes prevents changes in global joint metabolomic profiles in mouse post-traumatic osteoarthritis by Haudenschild, D.R., Carlson, A.K., Zignego, D.L., Yik, J.H.N., Hilmer, J.K., June, R.K.

“…Although joint injury itself damages joint tissues, a substantial amount of secondary damage is mediated by the cellular responses to the injury. Cellular…”
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Intensive herbicide use has selected for constitutively elevated levels of stress‐responsive mRNAs and proteins in multiple herbicide‐resistant Avena fatua L by Keith, Barbara K, Burns, Erin E, Bothner, Brian, Carey, Charles C, Mazurie, Aurélien J, Hilmer, Jonathan K, Biyiklioglu, Sezgi, Budak, Hikmet, Dyer, William E

“…BACKGROUND Intensive use of herbicides has led to the evolution of two multiple herbicide‐resistant (MHR) Avena fatua (wild oat) populations in Montana that…”
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Conformational Equilibria and Rates of Localized Motion within Hepatitis B Virus Capsids by Hilmer, Jonathan K., Zlotnick, Adam, Bothner, Brian

“…Functional analysis of hepatitis B virus (HBV) core particles has associated a number of biological roles with the C terminus of the capsid protein. One set of…”
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The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1 by Thomas, Celestine J, Briknarová, Klára, Hilmer, Jonathan K, Movahed, Navid, Bothner, Brian, Sumida, John P, Tall, Gregory G, Sprang, Stephen R

“…Heterotrimeric G protein α subunits are activated upon exchange of GDP for GTP at the nucleotide binding site of Gα, catalyzed by guanine nucleotide exchange…”
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Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression by Secor, Patrick R, Jennings, Laura K, James, Garth A, Kirker, Kelly R, Pulcini, Elinor Delancey, McInnerney, Kate, Gerlach, Robin, Livinghouse, Tom, Hilmer, Jonathan K, Bothner, Brian, Fleckman, Philip, Olerud, John E, Stewart, Philip S

“…Staphylococcus aureus biofilms are associated with chronic skin infections and are orders of magnitude more resistant to antimicrobials and host responses. S…”
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Expanding the paradigm of thiol redox in the thermophilic root of life by Heinemann, Joshua, Hamerly, Timothy, Maaty, Walid S., Movahed, Navid, Steffens, Joseph D., Reeves, Benjamin D., Hilmer, Jonathan K., Therien, Jesse, Grieco, Paul A., Peters, John W., Bothner, Brian

“…The current paradigm of intracellular redox chemistry maintains that cells establish a reducing environment maintained by a pool of small molecule and protein…”
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Characterization of the Archaeal Thermophile Sulfolobus Turreted Icosahedral Virus Validates an Evolutionary Link among Double-Stranded DNA Viruses from All Domains of Life by MAATY, Walid S. A, ORTMANN, Alice C, BOTHNER, Brian, DLAKIE, Mensur, SCHULSTAD, Katie, HILMER, Jonathan K, LIEPOLD, Lars, WEIDENHEFT, Blake, KHAYAT, Reza, DOUGLAS, Trevor, YOUNG, Mark J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids by Zignego, Donald L, Hilmer, Jonathan K, June, Ronald K

“…Abstract Chondrocytes are the sole cell type found in articular cartilage and are repeatedly subjected to mechanical loading in vivo . We hypothesized that…”
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Primary human chondrocytes respond to compression with phosphoproteomic signatures that include microtubule activation by Zignego, Donald L., Hilmer, Jonathan K., Bothner, Brian, Schell, William J., June, Ronald K.

“…Chondrocytes are responsible for maintaining the cartilage that helps joints bear load and move smoothly. These cells typically respond to physiological…”
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Mass Spectrometry Imaging of Chlorhexidine and Bacteria in a Model Wound by Hamerly, Timothy, H. Butler, Margaret, T. Fisher, Steve, K. Hilmer, Jonathan, A. James, Garth, Bothner, Brian

“…The ability to generate two-dimensional images of a wound that contains information about the distribution of bacteria overlaid with the distribution of drugs…”
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Solution phase dynamics of the DNA repair enzyme spore photoproduct lyase as probed by H/D exchange by Ghose, Shourjo, Hilmer, Jonathan K., Bothner, Brian, Broderick, Joan B.

“…•Significant reductions in H/D exchange were observed upon substrate binding.•Binding of SPTpT induced a shift of 20 amide protons to a protected…”
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Ultrafast Excited-State Deactivation of the Bacterial Pigment Violacein by Beckstead, Ashley A, Zhang, Yuyuan, Hilmer, Jonathan K, Smith, Heidi J, Bermel, Emily, Foreman, Christine M, Kohler, Bern

“…The photophysical properties of the natural pigment violacein extracted from an Antarctic organism adapted to high exposure levels of UV radiation were…”
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Ultrafast Excited-State Deactivation of the Bacterial Pigment Violacein by Beckstead, Ashley A, Zhang, Yuyuan, Hilmer, Jonathan K, Smith, Heidi J, Bermel, Emily, Foreman, Christine M, Kohler, Bern

“…The photophysical properties of the natural pigment violacein extracted from an Antarctic organism adapted to high exposure levels of UV radiation were…”
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Proteomic comparison of near-isogenic barley (Hordeum vulgare L.) germplasm differing in the allelic state of a major senescence QTL identifies numerous proteins involved in plant pathogen defense by Mason, Katelyn E., Hilmer, Jonathan K., Maaty, Walid S., Reeves, Benjamin D., Grieco, Paul A., Bothner, Brian, Fischer, Andreas M.

“…Senescence is the last developmental phase of plant tissues, organs and, in the case of monocarpic senescence, entire plants. In monocarpic crops such as…”
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Physical signal modulation of time-of-flight mass analyzers increases precision and decreases noise by Hilmer, Jonathan K., Bothner, Brian

“…Recently, an increased emphasis has been placed on the ability to make mass measurements with high accuracy and precision. The motivation for this is that…”
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Candidate mediators of chondrocyte mechanotransduction via targeted and untargeted metabolomic measurements by Jutila, Aaron A., Zignego, Donald L., Hwang, Bradley K., Hilmer, Jonathan K., Hamerly, Timothy, Minor, Cody A., Walk, Seth T., June, Ronald K.

“…•SW1353 chondrocytes were mechanically compressed in a physiologically stiff 3D environment.•Following compression, untargeted and targeted metabolomics…”
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Conversion of S-phenylsulfonylcysteine residues to mixed disulfides at pH 4.0: utility in protein thiol blocking and in protein-S-nitrosothiol detection by Reeves, B D, Joshi, N, Campanello, G C, Hilmer, J K, Chetia, L, Vance, J A, Reinschmidt, J N, Miller, C G, Giedroc, D P, Dratz, E A, Singel, D J, Grieco, P A

“…A three step protocol for protein S-nitrosothiol conversion to fluorescent mixed disulfides with purified proteins, referred to as the thiosulfonate switch, is…”
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Proteomic Analysis of Sulfolobus solfataricus during Sulfolobus Turreted Icosahedral Virus Infection by Maaty, Walid S, Selvig, Kyla, Ryder, Stephanie, Tarlykov, Pavel, Hilmer, Jonathan K, Heinemann, Joshua, Steffens, Joseph, Snyder, Jamie C, Ortmann, Alice C, Movahed, Navid, Spicka, Kevin, Chetia, Lakshindra, Grieco, Paul A, Dratz, Edward A, Douglas, Trevor, Young, Mark J, Bothner, Brian

“…Where there is life, there are viruses. The impact of viruses on evolution, global nutrient cycling, and disease has driven research on their cellular and…”
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Selective trapping of SNO-BSA and GSNO by benzenesulfinic acid sodium salt: mechanistic study of thiosulphonate formation and feasibility as a protein S -nitrosothiol detection strategy by Reeves, Benjamin D, Hilmer, Jonathan K, Mellmann, Lisa, Hartzheim, Myra, Poffenberger, Kevin, Johnson, Keith, Joshi, Neelambari, Singel, David J, Grieco, Paul A

“…The conversion of -nitrosothiols to thiosulphonates by reaction with the sodium salt of benzenesulfinic acid (PhSO Na) has been examined in detail with the…”
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