Search Results - "Hillsley, Kirk"
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Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice
Published in The Journal of physiology (01-11-2004)“…The aim of this study was to investigate the contribution of the TRPV1 receptor to jejunal afferent sensitivity in the murine intestine. Multiunit activity was…”
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Alterations in the Brain–Gut Axis Underlying Visceral Chemosensitivity in Nippostrongylus brasiliensis- Infected Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2007)“…Background & Aims: Visceral hypersensitivity, a hallmark of irritable bowel syndrome, is generally considered to be mechanosensitive in nature and mediated via…”
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Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice
Published in The Journal of physiology (01-10-2006)“…Tetrodotoxin-resistant (TTX-R) sodium currents have been proposed to underlie sensory neuronal hyperexcitability in acute inflammatory models, but their role…”
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Vagal influences over mast cells
Published in Autonomic neuroscience (30-04-2006)“…The established microanatomical association of rat intestinal mucosal mast cells (IMMC) and mucosal nerves raises the possibility that there is crosstalk…”
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Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavity
Published in Physiological genomics (23-02-2006)“…1 Johnson and Johnson Pharmaceutical Research and Development, Department of Internal Medicine, Beerse, Belgium 2 Holburn Group of Companies, Bowmanville,…”
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Role of ryanodine-sensitive stores in the afterhyperpolarization of S and AH neurons
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2000)Get full text
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Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Na v 1.8 and Na v 1.9 null mice
Published in The Journal of physiology (01-10-2006)“…Tetrodotoxin‐resistant (TTX‐R) sodium currents have been proposed to underlie sensory neuronal hyperexcitability in acute inflammatory models, but their role…”
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Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Na sub(v)1.8 and Na sub(v)1.9 null mice
Published in The Journal of physiology (01-10-2006)“…Tetrodotoxin-resistant (TTX-R) sodium currents have been proposed to underlie sensory neuronal hyperexcitability in acute inflammatory models, but their role…”
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Intrinsic serotonergic neurons of the guinea pig sphincter of oddi
Published in Gastroenterology (New York, N.Y. 1943) (15-04-1998)Get full text
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Intestinal afferent sensitivity to acid and distension in wild type and Vrl-/-knockout mice
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2003)Get full text
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Recording ionic events from cultured, DiI-labelled myenteric neurons in the guinea-pig proximal colon
Published in Journal of neuroscience methods (01-03-2000)“…To date investigations of enteric neurons by patch clamping/calcium imaging have been limited by studying unidentified heterogeneous populations of neurons. In…”
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Motor activity in the isolated jejunum of VR1 knockout mice
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2003)Get full text
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Cilansetron acts at its site of absorption to antagonize the sensitivity of mesenteric afferent fibres to 5-hydroxytryptamine in the rat jejunum
Published in Neuroscience letters (14-01-2000)“…The present study compares the efficacy of cilansetron, a 5-hydroxytryptamine (5-HT3)-receptor antagonist, delivered via intravenous and intraluminal routes,…”
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Diverse Ionic Currents and Electrical Activity of Cultured Myenteric Neurons From the Guinea Pig Proximal Colon
Published in Journal of neurophysiology (01-03-2000)“…Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557 Vogalis, Fivos, Kirk Hillsley, and Terence K. Smith…”
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Vagal influences over mast cells
Published in Autonomic neuroscience : basic & clinical (2006)Get full text
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Cholecystokinin depolarizes guinea pig sphincter of Oddi neurons by activating CCK-A receptors
Published in The American journal of physiology (01-06-1997)“…Motility studies indicate that cholecystokinin (CCK) acts through a neural mechanism in the sphincter of Oddi (SO) after meals. To evaluate its actions in SO…”
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Identification of the cholinergic neurons in Guinea-pig sphincter of Oddi ganglia
Published in Journal of the autonomic nervous system (12-05-1997)“…The muscular tone of the sphincter of Oddi (SO) can be up- or down-regulated by neurons that lie within ganglia in the wall of the tissue. Previous studies…”
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