Search Results - "Hills, L Benjamin"
-
1
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
Published in Cell (26-10-2012)“…A major unanswered question in neuroscience is whether there exists genomic variability between individual neurons of the brain, contributing to functional…”
Get full text
Journal Article -
2
Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
Published in Neuron (Cambridge, Mass.) (12-04-2012)“…Hemimegalencephaly (HMG) is a developmental brain disorder characterized by an enlarged, malformed cerebral hemisphere, typically causing epilepsy that…”
Get full text
Journal Article -
3
MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation
Published in PloS one (11-05-2017)“…Neurogenesis is a highly-regulated process occurring in the dentate gyrus that has been linked to learning, memory, and antidepressant efficacy. MicroRNAs…”
Get full text
Journal Article -
4
Immunological memory diversity in the human upper airway
Published in Nature (London) (15-08-2024)“…The upper airway is an important site of infection, but immune memory in the human upper airway is poorly understood, with implications for COVID-19 and many…”
Get full text
Journal Article -
5
Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans
Published in Neurology (15-10-2013)“…OBJECTIVE:To identify the genetic cause of a syndrome causing cerebellar ataxia and eye movement abnormalities. METHODS:We identified 2 families with…”
Get full text
Journal Article -
6
Diverse Roles of Akt in T cells
Published in Immunometabolism (Cobham) (01-01-2021)“…Abstract Akt kinases translate various external cues into intracellular signals that control cell survival, proliferation, metabolism and differentiation. This…”
Get full text
Journal Article -
7
Elucidating the role of the Mst1/Foxo1 axis in CD8+ memory T cell development
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract The Foxo1 transcription factor is required for naïve T cell homeostasis and trafficking, T regulatory cell development, and CD8 memory T cell…”
Get full text
Journal Article -
8
Mst1 regulates Foxo1 transcription to differentially control memory CD8 T cell differentiation and survival
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Foxo1 is an essential transcription factor required for the differentiation and survival of memory CD8 T cells. Foxo1 activity is heavily regulated by…”
Get full text
Journal Article