Search Results - "Hillman, Elizabeth MC"

3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images by Wen, Chentao, Miura, Takuya, Voleti, Venkatakaushik, Yamaguchi, Kazushi, Tsutsumi, Motosuke, Yamamoto, Kei, Otomo, Kohei, Fujie, Yukako, Teramoto, Takayuki, Ishihara, Takeshi, Aoki, Kazuhiro, Nemoto, Tomomi, Hillman, Elizabeth Mc, Kimura, Koutarou D

“…Despite recent improvements in microscope technologies, segmenting and tracking cells in three-dimensional time-lapse images (3D + T images) to extract their…”
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High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets by Hillman, Elizabeth MC, Voleti, Venkatakaushik, Patel, Kripa, Li, Wenze, Yu, Hang, Perez-Campos, Citlali, Benezra, Sam E, Bruno, Randy M, Galwaduge, Pubudu T

“…[Display omitted] •Neuroscience needs faster in vivo volumetric microscopy approaches.•Axially-extended beams and light sheets provide alternatives to point…”
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High-speed vascular dynamics of the hemodynamic response by Chen, Brenda R., Bouchard, Matthew B., McCaslin, Addason F.H., Burgess, Sean A., Hillman, Elizabeth M.C.

“…While a range of cellular mechanisms have been proposed to underlie control of neurovascular coupling, a comprehensive, reconciliatory model has yet to be…”
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Coupling mechanism and significance of the BOLD signal: a status report by Hillman, Elizabeth M C

“…Functional magnetic resonance imaging (fMRI) provides a unique view of the working human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in…”
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Light-Sheet Microscopy in Neuroscience by Hillman, Elizabeth M.C, Voleti, Venkatakaushik, Li, Wenze, Yu, Hang

“…Light-sheet microscopy is an imaging approach that offers unique advantages for a diverse range of neuroscience applications. Unlike point-scanning techniques…”
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Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons by Ma, Ying, Shaik, Mohammed A., Kozberg, Mariel G., Kim, Sharon H., Portes, Jacob P., Timerman, Dmitriy, Hillman, Elizabeth M. C.

“…Brain hemodynamics serve as a proxy for neural activity in a range of noninvasive neuroimaging techniques including functional magnetic resonance imaging…”
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Swept confocally-aligned planar excitation (SCAPE) microscopy for high-speed volumetric imaging of behaving organisms by Bouchard, Matthew B., Voleti, Venkatakaushik, Mendes, César S., Lacefield, Clay, Grueber, Wesley B., Mann, Richard S., Bruno, Randy M., Hillman, Elizabeth M. C.

“…We report a three-dimensional microscopy technique—swept, confocally-aligned planar excitation (SCAPE) microscopy—that allows volumetric imaging of living…”
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Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches by Ma, Ying, Shaik, Mohammed A., Kim, Sharon H., Kozberg, Mariel G., Thibodeaux, David N., Zhao, Hanzhi T., Yu, Hang, Hillman, Elizabeth M. C.

“…Although modern techniques such as two-photon microscopy can now provide cellular-level three-dimensional imaging of the intact living brain, the speed and…”
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Optical brain imaging in vivo: techniques and applications from animal to man by Hillman, Elizabeth M C

“…Optical brain imaging has seen 30 years of intense development, and has grown into a rich and diverse field. In-vivo imaging using light provides unprecedented…”
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in vivo 3D Morphology of Astrocyte—Vasculature Interactions in the Somatosensory Cortex: Implications for Neurovascular Coupling by McCaslin, Addason F H, Chen, Brenda R, Radosevich, Andrew J, Cauli, Bruno, Hillman, Elizabeth M C

“…Astrocytes are increasingly believed to play an important role in neurovascular coupling. Recent in vivo studies have shown that intracellular calcium levels…”
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Suppressed Neuronal Activity and Concurrent Arteriolar Vasoconstriction May Explain Negative Blood Oxygenation Level-Dependent Signal by Devor, Anna, Tian, Peifang, Nishimura, Nozomi, Teng, Ivan C, Hillman, Elizabeth M. C, Narayanan, S. N, Ulbert, Istvan, Boas, David A, Kleinfeld, David, Dale, Anders M

“…Synaptic transmission initiates a cascade of signal transduction events that couple neuronal activity to local changes in blood flow and oxygenation. Although…”
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Direct, intraoperative observation of ~0.1Hz hemodynamic oscillations in awake human cortex: Implications for fMRI by Rayshubskiy, Aleksandr, Wojtasiewicz, Teresa J., Mikell, Charles B., Bouchard, Matthew B., Timerman, Dmitriy, Youngerman, Brett E., McGovern, Robert A., Otten, Marc L., Canoll, Peter, McKhann, Guy M., Hillman, Elizabeth M.C.

“…An almost sinusoidal, large amplitude ~0.1Hz oscillation in cortical hemodynamics has been repeatedly observed in species ranging from mice to humans. However,…”
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Spatiotemporal precision and hemodynamic mechanism of optical point spreads in alert primates by Sirotin, Yevgeniy B, Hillman, Elizabeth M.C, Bordier, Clemence, Das, Aniruddha

“…In functional brain imaging there is controversy over which hemodynamic signal best represents neural activity. Intrinsic signal optical imaging (ISOI)…”
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Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation by Hillman, Elizabeth M.C., Devor, Anna, Bouchard, Matthew B., Dunn, Andrew K., Krauss, G.W., Skoch, Jesse, Bacskai, Brian J., Dale, Anders M., Boas, David A.

“…The cortical hemodynamic response to somatosensory stimulus is investigated at the level of individual vascular compartments using both depth-resolved optical…”
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Correction to ‘Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches’ by Ma, Ying, Shaik, Mohammed A., Kim, Sharon H., Kozberg, Mariel G., Thibodeaux, David N., Zhao, Hanzhi T., Yu, Hang, Hillman, Elizabeth M. C.

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An early endothelial cell-specific requirement for Glut1 is revealed in Glut1 deficiency syndrome model mice by Tang, Maoxue, Park, Sarah H, Petri, Sabrina, Yu, Hang, Rueda, Carlos B, Abel, E Dale, Kim, Carla Y, Hillman, Elizabeth Mc, Li, Fanghua, Lee, Yeojin, Ding, Lei, Jagadish, Smitha, Frankel, Wayne N, De Vivo, Darryl C, Monani, Umrao R

“…Paucity of the glucose transporter-1 (Glut1) protein resulting from haploinsufficiency of the SLC2A1 gene arrests cerebral angiogenesis and disrupts brain…”
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A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow by Qiu, Jun, Baik, Andrew D, Lu, X. Lucas, Hillman, Elizabeth M.C, Zhuang, Zhuo, Dong, Cheng, Guo, X. Edward

“…Abstract Mechanical properties of cells play an important role in their interaction with the extracellular matrix as well as the mechanotransduction process…”
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Simultaneous tracking of 3D actin and microtubule strains in individual MLO-Y4 osteocytes under oscillatory flow by Baik, Andrew D., Qiu, Jun, Hillman, Elizabeth M.C., Dong, Cheng, Guo, X. Edward

“…► Single-cell 3D osteocyte cytoskeletal mechanics were investigated. ► Actin and microtubule networks had similar creep behavior under steady fluid flow. ► The…”
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CAM-CM: a signal deconvolution tool for in vivo dynamic contrast-enhanced imaging of complex tissues by LI CHEN, CHAN, Tsung-Han, CHOYKE, Peter L, HILLMAN, Elizabeth M. C, CHI, Chong-Yung, BHUJWALLA, Zaver M, GE WANG, WANG, Sean S, SZABO, Zsolt, YUE WANG

“…In vivo dynamic contrast-enhanced imaging tools provide non-invasive methods for analyzing various functional changes associated with disease initiation,…”
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Quasi-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow by Baik, Andrew D., Lu, X. Lucas, Qiu, Jun, Huo, Bo, Hillman, Elizabeth M.C., Dong, Cheng, Guo, X. Edward

“…Osteocytes respond to dynamic fluid shear loading by activating various biochemical pathways, mediating a dynamic process of bone formation and resorption…”
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