Search Results - "Hiller, Luisa N"
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1
Comparative Genomic Analyses of 17 Clinical Isolates of Gardnerella vaginalis Provide Evidence of Multiple Genetically Isolated Clades Consistent with Subspeciation into Genovars
Published in Journal of Bacteriology (01-08-2012)“…Gardnerella vaginalis is associated with a spectrum of clinical conditions, suggesting high degrees of genetic heterogeneity among stains. Seventeen G…”
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The pneumococcal social network
Published in PLoS pathogens (29-10-2020)“…Gram-positive bacteria employ an array of secreted peptides to control population-level behaviors in response to environmental cues. We review mechanistic and…”
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3
Flexibility and constraint: Evolutionary remodeling of the sporulation initiation pathway in Firmicutes
Published in PLoS genetics (13-09-2018)“…The evolution of signal transduction pathways is constrained by the requirements of signal fidelity, yet flexibility is necessary to allow pathway remodeling…”
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4
Puzzling Over the Pneumococcal Pangenome
Published in Frontiers in microbiology (30-10-2018)“…The Gram positive bacterium (pneumococcus) is a major human pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and middle ear…”
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5
Environmental and genetic regulation of Streptococcus pneumoniae galactose catabolic pathways
Published in Nature communications (17-06-2024)“…Efficient utilization of nutrients is crucial for microbial survival and virulence. The same nutrient may be utilized by multiple catabolic pathways,…”
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Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
Published in Genome biology (29-10-2010)“…Streptococcus pneumoniae is one of the most important causes of microbial diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed…”
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A Host-Targeting Signal in Virulence Proteins Reveals a Secretome in Malarial Infection
Published in Science (American Association for the Advancement of Science) (10-12-2004)“…Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte, inducing modifications linked to disease and parasite survival. We…”
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Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3’ end formation in response to azithromycin
Published in PLoS genetics (12-07-2021)“…Pseudomonas aeruginosa produces serious chronic infections in hospitalized patients and immunocompromised individuals, including patients with cystic fibrosis…”
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Pneumococcal Extracellular Vesicles Modulate Host Immunity
Published in mBio (31-08-2021)“…Extracellular vesicles (EVs) have recently garnered attention for their participation in host-microbe interactions in pneumococcal infections. However, the…”
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10
Function of BriC peptide in the pneumococcal competence and virulence portfolio
Published in PLoS pathogens (01-10-2018)“…Streptococcus pneumoniae (pneumococcus) is an opportunistic pathogen that causes otitis media, sinusitis, pneumonia, meningitis and sepsis. The progression to…”
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11
A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation
Published in Molecular microbiology (01-08-2017)“…Summary Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common colonizer of the human respiratory track, where it utilizes cell–cell…”
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Generation of genic diversity among Streptococcus pneumoniae strains via horizontal gene transfer during a chronic polyclonal pediatric infection
Published in PLoS pathogens (01-09-2010)“…Although there is tremendous interest in understanding the evolutionary roles of horizontal gene transfer (HGT) processes that occur during chronic polyclonal…”
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13
The malaria secretome: from algorithms to essential function in blood stage infection
Published in PLoS pathogens (01-06-2008)“…The malaria agent Plasmodium falciparum is predicted to export a "secretome" of several hundred proteins to remodel the host erythrocyte. Prediction of protein…”
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14
Comparative Genomic Analyses of Seventeen Streptococcus pneumoniae Strains: Insights into the Pneumococcal Supragenome
Published in Journal of Bacteriology (01-11-2007)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
A HT/PEXEL Motif in Toxoplasma Dense Granule Proteins is a Signal for Protein Cleavage but not Export into the Host Cell
Published in Traffic (Copenhagen, Denmark) (01-05-2013)“…Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium, secrete proteins for attachment, invasion and modulation of their host cells. The host…”
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Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage
Published in PLoS pathogens (01-05-2017)“…Streptococcus pneumoniae (pneumococcus) is a leading cause of death and disease in children and elderly. Genetic variability among isolates from this species…”
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Detection of influenza virus and Streptococcus pneumoniae in air sampled from co-infected ferrets and analysis of their influence on pathogen stability
Published in mSphere (24-08-2023)“…Secondary infection with has contributed significantly to morbidity and mortality during multiple influenza virus pandemics and remains a common threat today…”
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Deletion of genes involved in the ketogluconate metabolism, Entner-Doudoroff pathway, and glucose dehydrogenase increase local and invasive virulence phenotypes in Streptococcus pneumoniae
Published in PloS one (08-01-2019)“…Streptococcus pneumoniae displays increased resistance to antibiotic therapy following biofilm formation. A genome-wide search revealed that SP 0320 and SP…”
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Comparative Genomic Analysis of Ten Streptococcus pneumoniae Temperate Bacteriophages
Published in Journal of Bacteriology (01-08-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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20
MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues
Published in Advanced science (01-10-2023)“…Super-resolution optical imaging tools are crucial in microbiology to understand the complex structures and behavior of microorganisms such as bacteria, fungi,…”
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