Water-Induced Thermogenesis

Water-Induced Thermogenesis

Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substra...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism Vol. 88; no. 12; pp. 6015 - 6019
Main Authors: Boschmann, Michael, Steiniger, Jochen, Hille, Uta, Tank, Jens, Adams, Frauke, Sharma, Arya M., Klaus, Susanne, Luft, Friedrich C., Jordan, Jens
Format: Journal Article
Language:English
Published: Bethesda, MD Endocrine Society 01-12-2003
Copyright by The Endocrine Society
Subjects:
Adipose Tissue - metabolism
Adrenergic beta-Antagonists - pharmacology
Adult
Biological and medical sciences
Calorimetry, Indirect
Carbohydrate Metabolism
Drinking - physiology
Energy Metabolism
Female
Humans
Lipid Metabolism
Male
Medical sciences
Microdialysis
Miscellaneous
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Reference Values
Respiratory Mechanics
Sex Characteristics
Thermogenesis - physiology
Time Factors
Water
Human
Thermogenesis
Healthy subject
Energetic cost
Female
Drinking
Experimental study
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Summary:Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substrate oxidation rates by using whole-room indirect calorimetry. The effect of water drinking on adipose tissue metabolism was assessed with the microdialysis technique. Drinking 500 ml of water increased metabolic rate by 30%. The increase occurred within 10 min and reached a maximum after 30–40 min. The total thermogenic response was about 100 kJ. About 40% of the thermogenic effect originated from warming the water from 22 to 37 C. In men, lipids mainly fueled the increase in metabolic rate. In contrast, in women carbohydrates were mainly used as the energy source. The increase in energy expenditure with water was diminished with systemic β-adrenoreceptor blockade. Thus, drinking 2 liters of water per day would augment energy expenditure by approximately 400 kJ. Therefore, the thermogenic effect of water should be considered when estimating energy expenditure, particularly during weight loss programs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2003-030780