Search Results - "Hillcoat, L"

MT39 Development of an Early Economic Model to Assess the Cost-Effectiveness of a Novel Technology for the Treatment and/or Prevention of Cataracts by Looby, A., Butler, K., Hillcoat, L.

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An economic evaluation of first-line cryoballoon ablation versus antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation from a German healthcare service payer perspective by Goette, A, Moss, J, Straube, F, Andrade, J, Wazni, O, Chierchia, G B, Schwegmann, L, Ismyrloglou, E, Sale, A, Hillcoat, L, Mealing, S, Bromilow, T, Lane, E, Lewis, D, Kuniss, M

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A pharmacokinetic and phase II study of gallium nitrate in patients with non-small cell lung cancer by WEBSTER, L. K, OLVER, I. N, STOKES, K. H, SEPHTON, R. G, HILLCOAT, B. L, BISHOP, J. F

“…This study investigated the pharmacokinetics and activity of gallium nitrate in non-small cell lung cancer when 700 mg/m2 was given as a 30-min infusion with…”
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A randomized trial of cisplatin versus cisplatin plus methotrexate in advanced cancer of the urothelial tract by Hillcoat, B L, Raghavan, D, Matthews, J, Kefford, R, Yuen, K, Woods, R, Olver, I, Bishop, J, Pearson, B, Coorey, G

“…One hundred eight patients with recurrent or metastatic transitional cell carcinoma of the urothelial tract were randomized to receive cisplatin (C) 80 mg/m2…”
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cis-Bis(pyridine)platinum(II) organoamides with unexpected growth inhibition properties and antitumor activity by Webster, Lorraine K, Deacon, Glen B, Buxton, David P, Hillcoat, Brian L, James, Alison M, Roos, Ian A. G, Thomson, Robin J, Wakelin, Laurence P. G, Williams, Tracey L

“…The platinum(II) organoamides [Pt(NRCH2)2L2] (L = pyridine (py), R = p-HC6F4, C6F5,p-IC6F4,p-CIC6F4,p-C6F5C6F4; L = 4-methylpyridine, R = p-HC6F4) and…”
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The changing face of clinical trials in Australia by Hillcoat, B L

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The binding of binuclear platinum(II)-terpyridine complexes to DNA by McFadyen, W D, Wakelin, L P, Roos, I A, Hillcoat, B L

“…The binding of platinum (II)-terpyridine complexes to DNA was studied by using equilibrium dialysis. Optical absorption methods were used to measure the…”
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Data recycling and misreading: two potential errors in pooled data from small studies by Hillcoat, B L

“…Data from studies on small numbers of patients are often pooled to obtain more significant numbers with which to estimate response rates to chemotherapy. This…”
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Binuclear platinum (II)-terpyridine complexes. A new class of bifunctional DNA-intercalating agent by McFadyen, W D, Wakelin, L P, Roos, I A, Hillcoat, B L

“…A series of binuclear DNA-binding ligands was prepared by linking two (2,2':6',2"-terpyridine)platinum(II) moieties via alpha omega-dithiols of the type…”
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Metallothionein induction in mouse tissues by cis-dichlorodiammineplatinum(II) and its hydrolysis products by Farnworth, P G, Hillcoat, B L, Roos, I A

“…cis-Dichlorodiammineplatinum(II) (cis-DDP) doubled the amount of metallothioneins (MTs) in the livers and kidneys of BALB/c mice when injected i.p. in a single…”
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Lorazepam: a randomized, double-blind, crossover study of a new antiemetic in patients receiving cytotoxic chemotherapy and prochlorperazine by Bishop, J F, Olver, I N, Wolf, M M, Matthews, J P, Long, M, Bingham, J, Hillcoat, B L, Cooper, I A

“…Lorazepam was compared to placebo to assess its control of nausea and vomiting in patients receiving cytotoxic chemotherapy and prochlorperazine. The study…”
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Phase II trial of VP-16-213 in advanced ovarian carcinoma by Hillcoat, B L, Campbell, J J, Pepperell, R, Quinn, M A, Bishop, J F, Day, A

“…We have reevaluated the effectiveness of VP-16-213 in advanced ovarian carcinoma. Twenty-five patients with measurable disease were treated for 3 days every 2…”
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Development of a murine gastric distension model for testing the emetic potential of new drugs and efficacy of antiemetics by Olver, I N, Roos, I A, Thomas, K, Hillcoat, B L

“…A small animal model for emesis would allow preclinical testing of antiemetics and new drugs. Mice treated with cisplatinum develop stomachs distended with…”
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Pharmacokinetic study of doxifluridine given by 5-day stepped-dose infusion by REECE, P. A, OLVER, I. N, MORRIS, R. G, BISHOP, J. F, GUENTERT, T. W, HILL, H. S, HILLCOAT, B. L

“…Doxifluridine (5'-deoxy-5-fluorouridine, 5'-dFUR) metabolism has been reported to be saturable and associated with a fall in clearance of the drug as the dose…”
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Rectal adenocarcinoma with germ cell elements treated with chemotherapy by Ostör, A G, McNaughton, W M, Fortune, D W, Rischin, D, Hillcoat, B L, Riley, C B

“…A patient with adenocarcinoma of the rectum containing germ cell elements in the form of endodermal sinus tumor and choriocarcinoma is described, believed to…”
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A phase I study of doxifluridine as a five-day stepped-dose continuous infusion by Olver, I N, Reece, P A, Bishop, J F, Morris, R G, Hillcoat, B L, Guentert, T W

“…Doxifluridine (5'-dFUR) is a prodrug of 5 fluorouracil (5-FU) synthesized in an attempt to improve the therapeutic index compared with 5-FU. In this phase I…”
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Clinical response and plasma levels of 5-fluorouracil in patients with colonic cancer treated by drug infusion by Hillcoat, B L, McCulloch, P B, Figueredo, A T, Ehsan, M H, Rosenfeld, J M

“…Concentrations of 5-fluorouracil (FU) were measured in the plasma of patients receiving i.v. infusions of the drug for 5 days as treatment for adenocarcinoma…”
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Determination of 6-mercaptopurine in plasma by mass spectrometry by Rosenfeld, J. M, Taguchi, V. Y, Hillcoat, B. L, Kawai, M

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Preparation and administration of antineoplastic agents. Risks and recommendations by Hillcoat, B L, Levi, J, Snyder, R

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Pharmacokinetics of unchanged carboplatin (CBDCA) in patients with small cell lung carcinoma by REECE, P. A, BISHOP, J. F, OLVER, I. N, STAFFORD, I, HILLCOAT, B. L, MORSTYN, G

“…The disposition of the cisplatin analogue carboplatin was studied in seven patients with small cell lung cancer. Carboplatin 100 mg/m2 was administered without…”
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