Search Results - "Hillas, Jessica"
-
1
Transcriptomic analysis of primary nasal epithelial cells reveals altered interferon signalling in preterm birth survivors at one year of age
Published in Frontiers in cell and developmental biology (24-07-2024)“…Many survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of…”
Get full text
Journal Article -
2
Preterm birth: Born too soon for the developing airway epithelium?
Published in Paediatric respiratory reviews (01-08-2019)“…Birth prior to term interrupts the normal development of the respiratory system and consequently results in poor respiratory outcomes that persist throughout…”
Get full text
Journal Article -
3
Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter
Published in Nature communications (30-11-2022)“…Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility…”
Get full text
Journal Article -
4
In Vitro primary human airway epithelial whole exhaust exposure
Published in MethodsX (01-01-2021)“…The method outlined in this article is a customization of the whole exhaust exposure method generated by Mullins et al. (2016) using reprogrammed primary human…”
Get full text
Journal Article -
5
Nasal airway epithelial repair after very preterm birth
Published in ERJ open research (01-04-2021)“…Preterm birth rates are increasing and now account for >11% of global births. Simultaneously, advances in neonatal care have led to increased survival of lower…”
Get full text
Journal Article -
6
Toxicity of different biodiesel exhausts in primary human airway epithelial cells grown at air-liquid interface
Published in The Science of the total environment (01-08-2022)“…Biodiesel is created through the transesterification of fats/oils and its usage is increasing worldwide as global warming concerns increase. Biodiesel fuel…”
Get full text
Journal Article -
7
Fuel feedstock determines biodiesel exhaust toxicity in a human airway epithelial cell exposure model
Published in Journal of hazardous materials (15-10-2021)“…Biodiesel is promoted as a sustainable replacement for commercial diesel. Biodiesel fuel and exhaust properties change depending on the base feedstock oil/fat…”
Get full text
Journal Article -
8
Biodiesel feedstock determines exhaust toxicity in 20% biodiesel: 80% mineral diesel blends
Published in Chemosphere (Oxford) (01-01-2023)“…To address climate change concerns, and reduce the carbon footprint caused by fossil fuel use, it is likely that blend ratios of renewable biodiesel with…”
Get full text
Journal Article -
9
Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium
Published in Journal of allergy and clinical immunology (01-06-2020)“…Emerging evidence suggests that disease vulnerability is expressed throughout the airways, the so-called unified airway hypothesis, but the evidence to support…”
Get full text
Journal Article -
10
Development and validation of a miniaturized bacteriophage host range screening assay against antibiotic resistant Pseudomonas aeruginosa
Published in Journal of microbiological methods (01-11-2021)“…Antimicrobial resistance is a current global health crisis, and the increasing emergence of multidrug resistant infections has led to the resurgent interest in…”
Get full text
Journal Article -
11
Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial Cells
Published in Environmental science & technology (01-10-2019)“…As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young…”
Get full text
Journal Article -
12
Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients
Published in Respirology (Carlton, Vic.) (01-12-2019)“…ABSTRACT Background and objective Human rhinovirus (RV) is a common upper and lower respiratory pathogen in lung allograft recipients causing respiratory tract…”
Get full text
Journal Article -
13
Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus
Published in Journal of cystic fibrosis (01-01-2021)“…•Measured gene responses by primary CF epithelial cells to rhinovirus using RNAseq.•Both P.Phe508del homozygous and P.Phe508del/pGly551Asp cells were…”
Get full text
Journal Article -
14
Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze
Published in Journal of personalized medicine (07-12-2021)“…The airway epithelium of children with wheeze is characterized by defective repair that contributes to disease pathobiology. Dysregulation of developmental…”
Get full text
Journal Article -
15
Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze
Published in JCI insight (09-04-2020)“…Abnormal wound repair has been observed in the airway epithelium of patients with chronic respiratory diseases, including asthma. Therapies focusing on…”
Get full text
Journal Article