Whole egg consumption and cortical bone in healthy children

Whole egg consumption and cortical bone in healthy children

Summary Eggs contain bioactive compounds thought to benefit pediatric bone. This cross-sectional study shows a positive link between childhood egg intake and radius cortical bone. If randomized trials confirm our findings, incorporating eggs into children’s diets could have a significant impact in p...

Full description

Saved in:
Bibliographic Details
Published in:Osteoporosis international Vol. 29; no. 8; pp. 1783 - 1791
Main Authors: Coheley, L.M., Kindler, J.M., Laing, E.M., Oshri, A., Hill Gallant, K.M., Warden, S.J., Peacock, M., Weaver, C.M., Lewis, R.D.
Format: Journal Article
Language:English
Published: London Springer London 01-08-2018
Springer Nature B.V
Subjects:
Bioactive compounds
Biomarkers
Body composition
Bone composition
Bone mineral content
Bone mineral density
Bone turnover
Children
Children & youth
Computed tomography
Cortical bone
Diet
Dual energy X-ray absorptiometry
Eggs
Endocrinology
Enzyme-linked immunosorbent assay
Fat-free body mass
Fractures
Medicine
Medicine & Public Health
Original Article
Orthopedics
Osteocalcin
Osteoporosis
Pediatrics
Radius
Rheumatology
Tibia
Fat-free soft tissue
Egg
pQCT
Cortical bone
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Eggs contain bioactive compounds thought to benefit pediatric bone. This cross-sectional study shows a positive link between childhood egg intake and radius cortical bone. If randomized trials confirm our findings, incorporating eggs into children’s diets could have a significant impact in preventing childhood fractures and reducing the risk of osteoporosis. Introduction This study examined the relationships between egg consumption and cortical bone in children. Methods The cross-sectional study design included 294 9–13-year-old black and white males and females. Three-day diet records determined daily egg consumption. Peripheral quantitative computed tomography measured radius and tibia cortical bone. Body composition and biomarkers of bone turnover were assessed using dual-energy X-ray absorptiometry and ELISA, respectively. Results Egg intake was positively correlated with radius and tibia cortical bone mineral content (Ct.BMC), total bone area, cortical area, cortical thickness, periosteal circumference, and polar strength strain index in unadjusted models ( r  = 0.144–0.224, all P  < 0.050). After adjusting for differences in race, sex, maturation, fat-free soft tissue mass (FFST), and protein intakes, tibia relationships were nullified; however, egg intake remained positively correlated with radius Ct.BMC ( r  = 0.138, P  = 0.031). Egg intake positively correlated with total body bone mineral density, BMC, and bone area in the unadjusted models only ( r  = 0.119–0.224; all P  < 0.050). After adjusting for covariates, egg intake was a positive predictor of radius FFST ( β  = 0.113, P  < 0.050) and FFST was a positive predictor of Ct.BMC ( β  = 0.556, P  < 0.050) in path analyses. There was a direct influence of egg on radius Ct.BMC ( β  = 0.099, P  = 0.035), even after adjusting for the mediator, FFST ( β  = 0.137, P  = 0.020). Egg intake was positively correlated with osteocalcin in both the unadjusted ( P  = 0.005) and adjusted ( P  = 0.049) models. Conclusion If the positive influence of eggs on Ct.BMC observed in this study is confirmed through future randomized controlled trials, whole eggs may represent a viable strategy to promote pediatric bone development and prevent fractures.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-018-4538-1