Search Results - "Hill, Tyler F"

Human plasma cells engineered to secrete bispecifics drive effective in vivo leukemia killing by Hill, Tyler F, Narvekar, Parnal, Asher, Gregory D, Edelstein, Jasmine N, Camp, Nathan D, Grimm, Annaiz, Thomas, Kerri R, Leiken, Michael D, Molloy, Katherine M, Cook, Peter J, Arlauckas, Sean P, Morgan, Richard A, Tasian, Sarah K, Rawlings, David J, James, Richard G

“…Bispecific antibodies are an important tool for the management and treatment of acute leukemias. As a next step toward clinical translation of engineered…”
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409 Development of ex vivo precision gene engineered B cell medicines that produce highly active and sustained levels of transgenic anti-tumor biologics by Edelstein, Jasmine N, Hill, Tyler F, Leiken, Michael D, Molloy, Katherine M, Adekanye, Glory, Bullock, Caroline, Lazorchak, Adam S, Aryee, Ken-Edwin, Rawlings, David J, James, Richard G, Morgan, Richard A, Arlauckas, Sean P

“…BackgroundBispecific T Cell Engagers (BiTEs), consisting of an anti-CD3 scFv fused to an anti-tumor antigen scFv, are highly effective in the treatment of…”
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Engineered Plasma Cells: A Novel Platform for Long-Term Delivery of Biologics to Treat Leukemia and Other Diseases by Hill, Tyler F

“…Advances in genome-engineering have enabled the generation of human plasma cells that secrete therapeutic proteins and are capable of long-term in vivo…”
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409 Development ofex vivo precision gene engineered B cell medicines that produce highly active and sustained levels of transgenic anti-tumor biologics by Edelstein, Jasmine N, Hill, Tyler F, Leiken, Michael D, Molloy, Katherine M, Adekanye, Glory, Bullock, Caroline, Lazorchak, Adam S, Ken-Edwin Aryee, Rawlings, David J, James, Richard G, Morgan, Richard A, Arlauckas, Sean P

“…BackgroundBispecific T Cell Engagers (BiTEs), consisting of an anti-CD3 scFv fused to an anti-tumor antigen scFv, are highly effective in the treatment of…”
Get full text