Search Results - "Hill, Matthew"

Recent Strategies for the Synthesis of Pyridine Derivatives by Hill, Matthew D.

“…Recent advances in pyridine synthesis are described. Modification of traditional condensation strategies continues to be a recurrent theme in contemporary…”
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The multiplex model of the genetics of Alzheimer’s disease by Sims, Rebecca, Hill, Matthew, Williams, Julie

“…Genes play a strong role in Alzheimer’s disease (AD), with late-onset AD showing heritability of 58–79% and early-onset AD showing over 90%. Genetic…”
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Hippo pathway deficiency reverses systolic heart failure after infarction by Leach, John P., Heallen, Todd, Zhang, Min, Rahmani, Mahdis, Morikawa, Yuka, Hill, Matthew C., Segura, Ana, Willerson, James T., Martin, James F.

“…Deletion of the Hippo pathway component Salvador in mouse hearts with established ischaemic heart failure after myocardial infarction induces a reparative…”
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Low-Energy CO2 Release from Metal–Organic Frameworks Triggered by External Stimuli by Li, Haiqing, Hill, Matthew R

“…Groundbreaking research over the past 15 years has established metal–organic frameworks (MOFs) as adsorbents capable of unprecedented gas adsorption capacity…”
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Neurobiological Interactions Between Stress and the Endocannabinoid System by Morena, Maria, Patel, Sachin, Bains, Jaideep S, Hill, Matthew N

“…Stress affects a constellation of physiological systems in the body and evokes a rapid shift in many neurobehavioral processes. A growing body of work…”
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Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder by Hill, Matthew N, Campolongo, Patrizia, Yehuda, Rachel, Patel, Sachin

“…Exposure to stress is an undeniable, but in most cases surmountable, part of life. However, in certain individuals, exposure to severe or cumulative stressors…”
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Applications of Fluorine in Medicinal Chemistry by Gillis, Eric P, Eastman, Kyle J, Hill, Matthew D, Donnelly, David J, Meanwell, Nicholas A

“…The role of fluorine in drug design and development is expanding rapidly as we learn more about the unique properties associated with this unusual element and…”
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Amygdala FAAH and anandamide: mediating protection and recovery from stress by Gunduz-Cinar, Ozge, Hill, Matthew N, McEwen, Bruce S, Holmes, Andrew

“…Highlights • Fatty acid amide hydrolase (FAAH) regulates CB1R signaling in anxiety mediating brain regions. • Increasing endogenous levels of anandamide could…”
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A global assessment of climatic niche shifts and human influence in insect invasions by Hill, Matthew P., Gallardo, Belinda, Terblanche, John S.

“…Aim: Non-native invasive insects have major impacts on ecosystem function, agricultural production and human health. To predict the geographical distributions…”
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Efficient metal ion sieving in rectifying subnanochannels enabled by metal–organic frameworks by Lu, Jun, Zhang, Huacheng, Hou, Jue, Li, Xingya, Hu, Xiaoyi, Hu, Yaoxin, Easton, Christopher D., Li, Qinye, Sun, Chenghua, Thornton, Aaron W., Hill, Matthew R., Zhang, Xiwang, Jiang, Gengping, Liu, Jefferson Zhe, Hill, Anita J., Freeman, Benny D., Jiang, Lei, Wang, Huanting

“…Biological ion channels have remarkable ion selectivity, permeability and rectification properties, but it is challenging to develop artificial analogues…”
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Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial by Mayo, Leah M., Asratian, Anna, Lindé, Johan, Morena, Maria, Haataja, Roosa, Hammar, Valter, Augier, Gaëlle, Hill, Matthew N., Heilig, Markus

“…Posttraumatic stress disorder, an area of large unmet medical needs, is characterized by persistence of fear memories and maladaptive stress responses. In…”
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Mechanisms of stress in the brain by McEwen, Bruce S, Bowles, Nicole P, Gray, Jason D, Hill, Matthew N, Hunter, Richard G, Karatsoreos, Ilia N, Nasca, Carla

“…The brain perceives and adapts to stressors via multiple interacting molecular mechanisms involving the cell surface, cytoskeleton and epigenetic regulation…”
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Programmed Pore Architectures in Modular Quaternary Metal–Organic Frameworks by Liu, Lujia, Konstas, Kristina, Hill, Matthew R, Telfer, Shane G

“…To generate metal–organic frameworks (MOFs) that are complex and modular yet well ordered, we present a strategy employing a family of three topologically…”
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Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play by VanRyzin, Jonathan W., Marquardt, Ashley E., Argue, Kathryn J., Vecchiarelli, Haley A., Ashton, Sydney E., Arambula, Sheryl E., Hill, Matthew N., McCarthy, Margaret M.

“…Brain sex differences are established developmentally and generate enduring changes in circuitry and behavior. Steroid-mediated masculinization of the rat…”
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Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis by Xiao, Yang, Hill, Matthew C, Li, Lele, Deshmukh, Vaibhav, Martin, Thomas J, Wang, Jun, Martin, James F

“…Cardiac fibroblasts (CFs) respond to injury by transitioning through multiple cell states, including resting CFs, activated CFs, and myofibroblasts. We report…”
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Capture, Storage, and Release of Oxygen by Metal–Organic Frameworks (MOFs) by Sutton, Ashley L., Melag, Leena, Sadiq, M. Munir, Hill, Matthew R.

“…Oxygen is a critical gas for medical and industrial settings. Much of today's global oxygen supply is via inefficient technologies such as cryogenic…”
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From species distributions to climate change adaptation: Knowledge gaps in managing invertebrate pests in broad-acre grain crops by Macfadyen, Sarina, McDonald, Garrick, Hill, Matthew P.

“…•Current management options for grains’ pests are maladaptive to climate change.•We show how pest species’ distributions may respond to changing climate in…”
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Fast and selective fluoride ion conduction in sub-1-nanometer metal-organic framework channels by Li, Xingya, Zhang, Huacheng, Wang, Peiyao, Hou, Jue, Lu, Jun, Easton, Christopher D., Zhang, Xiwang, Hill, Matthew R., Thornton, Aaron W., Liu, Jefferson Zhe, Freeman, Benny D., Hill, Anita J., Jiang, Lei, Wang, Huanting

“…Biological fluoride ion channels are sub-1-nanometer protein pores with ultrahigh F − conductivity and selectivity over other halogen ions. Developing…”
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Transfer learning enables predictions in network biology by Theodoris, Christina V., Xiao, Ling, Chopra, Anant, Chaffin, Mark D., Al Sayed, Zeina R., Hill, Matthew C., Mantineo, Helene, Brydon, Elizabeth M., Zeng, Zexian, Liu, X. Shirley, Ellinor, Patrick T.

“…Mapping gene networks requires large amounts of transcriptomic data to learn the connections between genes, which impedes discoveries in settings with limited…”
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Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development by Xiao, Yang, Hill, Matthew C., Zhang, Min, Martin, Thomas J., Morikawa, Yuka, Wang, Suya, Moise, Alexander R., Wythe, Joshua D., Martin, James F.

“…During development, progenitors progress through transition states. The cardiac epicardium contains progenitors of essential non-cardiomyocytes. The Hippo…”
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