Search Results - "Hill, Mark D"

Design Tradeoffs in CXL-Based Memory Pools for Public Cloud Platforms by Berger, Daniel S., Ernst, Daniel, Li, Huaicheng, Zardoshti, Pantea, Shah, Monish, Rajadnya, Samir, Lee, Scott, Hsu, Lisa, Agarwal, Ishwar, Hill, Mark D., Bianchini, Ricardo

“…DRAM is a key driver of performance and cost in public cloud servers. At the same time, a significant amount of DRAM is underutilized due to fragmented use…”
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The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer's Disease by Chadwick, Wayne, Maudsley, Stuart, Hull, William, Havolli, Enes, Boshoff, Eugene, Hill, Mark D W, Goetghebeur, Pascal J D, Harrison, David C, Nizami, Sohaib, Bedford, David C, Coope, Gareth, Real, Katia, Thiemermann, Christoph, Maycox, Peter, Carlton, Mark, Cole, Sarah L

“…Sporadic Alzheimer's disease (sAD) represents a serious and growing worldwide economic and healthcare burden. Almost 95% of current AD patients are associated…”
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Amdahl's Law in the Multicore Era by Hill, M.D., Marty, M.R.

“…Augmenting Amdahl's law with a corollary for multicore hardware makes it relevant to future generations of chips with multiple processor cores. Obtaining…”
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On the Spectre and Meltdown Processor Security Vulnerabilities by Hill, Mark D., Masters, Jon, Ranganathan, Parthasarathy, Turner, Paul, Hennessy, John L.

“…This paper first reviews the Spectre and Meltdown processor security vulnerabilities that were revealed during January–October 2018 and that allow the…”
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Retrospective on Amdahl's Law in the Multicore Era by Hill, Mark D., Marty, Michael R.

“…The authors of a 2008 Computer article reflect on their corollaries to Amdahl's law almost 10 years later…”
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Agile Paging for Efficient Memory Virtualization by Gandhi, Jayneel, Hill, Mark D., Swift, Michael M.

“…Virtualization provides benefits for many workloads, but the overheads of virtualizing memory are still high. The cost comes from managing two levels of…”
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Supporting Very Large DRAM Caches with Compound-Access Scheduling and MissMap by Loh, G., Hill, M. D.

“…This work efficiently enables conventional block sizes for very large die-stacked DRAM caches with two innovations: it makes hits faster with compound-access…”
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Redundant Memory Mappings for fast access to large memories by Karakostas, Vasileios, Gandhi, Jayneel, Ayar, Furkan, Cristal, Adrian, Hill, Mark D., McKinley, Kathryn S., Nemirovsky, Mario, Swift, Michael M., Unsal, Osman

“…Page-based virtual memory improves programmer productivity, security, and memory utilization, but incurs performance overheads due to costly page table walks…”
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Range Translations for Fast Virtual Memory by Gandhi, Jayneel, Karakostas, Vasileios, Ayar, Furkan, Cristal, Adrian, Hill, Mark D., McKinley, Kathryn S., Nemirovsky, Mario, Swift, Michael M., Unsal, Osman S.

“…Modern workloads suffer high execution-time overhead due to page-based virtual memory. The authors introduce range translations that map arbitrary-sized…”
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Security Implications of Third-Party Accelerators by Olson, Lena E., Sethumadhavan, Simha, Hill, Mark D.

“…Third-party accelerators offer system designers high performance and low energy without the market delay of in-house development. However, complex third-party…”
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Proprietary versus Open Instruction Sets by Hill, Mark D., Christie, Dave, Patterson, David, Yi, Joshua J., Chiou, Derek, Sendag, Resit

“…This article presents position statements and a question-and-answer session by panelists at the 4th Workshop on Computer Architecture Research Directions. The…”
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Energy-efficient address translation by Karakostas, Vasileios, Gandhi, Jayneel, Cristal, Adrian, Hill, Mark D., McKinley, Kathryn S., Nemirovsky, Mario, Swift, Michael M., Unsal, Osman S.

“…Address translation is fundamental to processor performance. Prior work focused on reducing Translation Lookaside Buffer (TLB) misses to improve performance…”
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MRI detects early hindlimb muscle atrophy in Gly93Ala superoxide dismutase-1 (G93A SOD1) transgenic mice, an animal model of familial amyotrophic lateral sclerosis by Brooks, Keith J., Hill, Mark D. W., Hockings, Paul D., Reid, David G.

“…MRI has been used to measure hindlimb muscle volume in female and male transgenic mice overexpressing the Gly93Ala (G93A) mutant human superoxide dismutase 1…”
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LogTM-SE: Decoupling Hardware Transactional Memory from Caches by Yen, L., Bobba, J., Marty, M.R., Moore, K.E., Volos, H., Hill, M.D., Swift, M.M., Wood, D.A.

“…This paper proposes a hardware transactional memory (HTM) system called LogTM Signature Edition (LogTM-SE). LogTM-SE uses signatures to summarize a…”
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Antipsychotic Treatment Alters Protein Expression Associated with Presynaptic Function and Nervous System Development in Rat Frontal Cortex by Ma, Dan, Chan, Man K, Lockstone, Helen E, Pietsch, Sandra R, Jones, Declan N. C, Cilia, Jackie, Hill, Mark D, Robbins, Melanie J, Benzel, Isabel M, Umrania, Yagnesh, Guest, Paul C, Levin, Yishai, Maycox, Peter R, Bahn, Sabine

“…Haloperidol and olanzapine are widely used antipsychotic drugs in the treatment of schizophrenia and other psychotic disorders. Despite extensive research…”
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96 Decitabine gene modulation sensitizes human non–small cell lung cancer (NSCLC) to NY-ESO-1 TCR immunotherapy (letetresgene autoleucel; GSK3377794) in vivo by Pankov, Dmitry, Eleftheriadou, Ioanna, Domogala, Anna, Brett, Sara, Patasic, Lea, Kijewska, Magdalena, Thripp, Gary, Euesden, Jack, Klapwijk, Jan, Soor, Katrina, Damm, Miriam, Hill, Mark D, Georgouli, Mirella, Shalabi, Aiman, Britten, Cedrik

“…BackgroundNY-ESO-1–specific T cells (letetresgene autoleucel [lete-cel] GSK3377794) are autologous CD4+ and CD8+ T cells transduced to express a high-affinity…”
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Spatial recognition test: A novel cognition task for assessing topographical memory in mice by Havolli, Enes, Hill, Mark DW, Godley, Annie, Goetghebeur, Pascal JD

“…Dysfunction in topographical memory is a core feature of several neurological disorders. There is a large unmet medical need to address learning and memory…”
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Challenges in computer architecture evaluation by Skadron, K., Martonosi, M., August, D.I., Hill, M.D., Lilja, D.J., Pai, V.S.

“…We focus on problems suited to the current evaluation infrastructure. The current limitation and trends in evaluation techniques are troublesome and could…”
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Data page layouts for relational databases on deep memory hierarchies by AILAMAKI, Anastassia, DEWITT, David J, HILL, Mark D

“…Relational database systems have traditionally optimized for I/O performance and organized records sequentially on disk pages using the N-ary Storage Model…”
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Multiprocessors should support simple memory consistency models by Hill, M.D.

“…In the future, many computers will contain multiple processors, in part because the marginal cost of adding a few additional processors is so low that only…”
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