Search Results - "Hill, Joseph"
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Metabolic inflammation in heart failure with preserved ejection fraction
Published in Cardiovascular research (21-01-2021)“…Abstract One in 10 persons in the world aged 40 years and older will develop the syndrome of HFpEF (heart failure with preserved ejection fraction), the most…”
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The American Heart Association Journals Centennial Collection
Published in Circulation (New York, N.Y.) (09-01-2024)Get full text
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Pathological Ventricular Remodeling: Mechanisms: Part 1 of 2
Published in Circulation (New York, N.Y.) (23-07-2013)“…Despite declines in heart failure morbidity and mortality with current therapies, rehospitalization rates remain distressingly high, substantially affecting…”
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Branching out: new insights into the genetic regulation of shoot architecture in trees
Published in Current opinion in plant biology (01-02-2019)“…•Genes behind dwarf, weeping, and pillar tree growth habits have been identified.•There are multiple routes that lead to dwarfed tree statures.•Tree branch…”
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Fibrosis — A Common Pathway to Organ Injury and Failure
Published in The New England journal of medicine (19-03-2015)“…Fibrosis is a consequence of the inflammatory response. When fibrotic tissue becomes excessive, it can have diverse pathophysiological effects on a number of…”
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Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload
Published in Circulation (New York, N.Y.) (21-04-2015)Get full text
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The Arabidopsis Cellulose Synthase Complex: A Proposed Hexamer of CESA Trimers in an Equimolar Stoichiometry
Published in The Plant cell (01-12-2014)“…Cellulose is the most abundant renewable polymer on Earth and a major component of the plant cell wall. In vascular plants, cellulose synthesis is catalyzed by…”
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Pathogenesis of Myocardial Ischemia-Reperfusion Injury and Rationale for Therapy
Published in The American journal of cardiology (01-08-2010)“…Since the initial description of the phenomenon by Jennings et al 50 years ago, our understanding of the underlying mechanisms of reperfusion injury has grown…”
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Therapeutic targeting of autophagy in cardiovascular disease
Published in Journal of molecular and cellular cardiology (01-06-2016)“…Abstract Autophagy is an evolutionarily ancient process of intracellular catabolism necessary to preserve cellular homeostasis in response to a wide variety of…”
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Obesity, Diabetes, and Cardiovascular Diseases: A Compendium
Published in Circulation research (27-05-2016)Get full text
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Overrepresentation of Whiteness Is in Sign Language As Well: A Commentary on “Undoing Competence: Coloniality, Homogeneity, and the Overrepresentation of Whiteness in Applied Linguistics”
Published in Language learning (01-12-2023)“…This commentary is a response to Nelson Flores and Jonathan Rosa's article "Undoing Competence: Coloniality, Homogeneity, and the Overrepresentation of…”
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Heart Failure With Preserved Ejection Fraction: Heterogeneous Syndrome, Diverse Preclinical Models
Published in Circulation research (10-06-2022)“…Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest challenges facing cardiovascular medicine today. Despite being the most…”
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Readers, Writers, and Erasers: Chromatin as the Whiteboard of Heart Disease
Published in Circulation research (27-03-2015)“…Dynamic packaging of DNA into strings of nucleosomes is a major mechanism whereby eukaryotic cells regulate gene expression. Intricate control of nucleosomal…”
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Autophagy in cardiovascular biology
Published in The Journal of clinical investigation (01-01-2015)“…Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular…”
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Mitochondrial dynamics, mitophagy and cardiovascular disease
Published in The Journal of physiology (01-02-2016)“…Cardiac hypertrophy is often initiated as an adaptive response to haemodynamic stress or myocardial injury, and allows the heart to meet an increased demand…”
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Cardiac Plasticity
Published in The New England journal of medicine (27-03-2008)“…This review explains how the heart responds to physiologic or pathologic conditions. Exercise, pregnancy, and postnatal growth cause physiologic growth;…”
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When the CAR Targets Scar
Published in The New England journal of medicine (19-12-2019)“…Chimeric antigen receptor T cells, engineered to recognize fibroblast-activated protein, reduce fibrosis and partially restore function in a mouse model of…”
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Protein Quality Control and Metabolism: Bidirectional Control in the Heart
Published in Cell metabolism (03-02-2015)“…The prevalence of heart disease, especially heart failure, continues to increase, and cardiovascular disease remains the leading cause of death worldwide. As…”
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A coagulation factor moonlights in the heart
Published in Science (American Association for the Advancement of Science) (23-09-2022)“…Liver-derived coagulation factor XI protects the heart from failure Heart failure and liver diseases are among the most common causes of morbidity and…”
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Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys
Published in Autophagy (02-12-2019)“…Ischemic preconditioning (IPC) affords tissue protection in organs including kidneys; however, the underlying mechanism remains unclear. Here we demonstrate an…”
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