Search Results - "Hill, Jason E"
-
1
Longitudinal Analysis of Neural Network Development in Preterm Infants
Published in Cerebral cortex (New York, N.Y. 1991) (01-12-2010)“…Application of resting state functional connectivity magnetic resonance imaging (fcMRI) to the study of prematurely born infants enables assessment of the…”
Get full text
Journal Article -
2
Small Molecules That Reactivate p53 in Renal Cell Carcinoma Reveal a NF-κB-Dependent Mechanism of p53 Suppression in Tumors
Published in Proceedings of the National Academy of Sciences - PNAS (29-11-2005)“…Renal cell carcinomas (RCC) commonly retain wild-type but functionally inactive p53, which is repressed by an unknown dominant mechanism. To help reveal this…”
Get full text
Journal Article -
3
The impact of FLT3 mutation clearance and treatment response after gilteritinib therapy on overall survival in patients with FLT3 mutation–positive relapsed/refractory acute myeloid leukemia
Published in Cancer medicine (Malden, MA) (01-02-2021)“…The FLT3 inhibitor gilteritinib has clinical activity in patients with FLT3‐mutated (FLT3mut+) relapsed/refractory (R/R) acute myeloid leukemia (AML). The…”
Get full text
Journal Article -
4
Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells
Published in Proceedings of the National Academy of Sciences - PNAS (19-06-2007)“…The human EGF receptor (HER) 2 receptor tyrosine kinase is a survival factor for human cardiomyocytes, and its inhibition may explain the increased incidence…”
Get full text
Journal Article -
5
p53 pathway in renal cell carcinoma is repressed by a dominant mechanism
Published in Cancer research (Chicago, Ill.) (15-03-2004)“…Renal cell carcinoma (RCC) rarely acquires mutations in p53 tumor suppressor gene, suggesting that p53 signaling in this tumor type might be repressed by some…”
Get full text
Journal Article -
6
Down-Regulation of p53 by Double-Stranded RNA Modulates the Antiviral Response
Published in Journal of Virology (01-09-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
7
Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib
Published in Blood advances (12-04-2022)“…The phase 3 Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase…”
Get full text
Journal Article -
8
PCR-Based Subtractive Hybridization and Differences in Gene Content among Strains of Helicobacter pylori
Published in Proceedings of the National Academy of Sciences - PNAS (27-10-1998)“…Genes that are characteristic of only certain strains of a bacterial species can be of great biologic interest. Here we describe a PCR-based subtractive…”
Get full text
Journal Article -
9
The role of MRI in understanding the underlying mechanisms in obesity associated diseases
Published in Biochimica et biophysica acta. Molecular basis of disease (01-05-2017)“…Obesity and its possible association with diseases including diabetes and cardiovascular diseases have been studied for decades for its impact on healthcare…”
Get full text
Journal Article -
10
Gilteritinib in Combination With Induction and Consolidation Chemotherapy and as Maintenance Therapy: A Phase IB Study in Patients With Newly Diagnosed AML
Published in Journal of clinical oncology (10-09-2023)“…Gilteritinib is a type 1 FLT3 inhibitor active as monotherapy for relapsed or refractory -mutated AML. We investigated the safety, tolerability, and efficacy…”
Get full text
Journal Article -
11
Gilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations
Published in Blood advances (11-02-2020)“…Gilteritinib is the first FMS-like tyrosine kinase 3 (FLT3) tyrosine kinase inhibitor (TKI) approved as monotherapy in acute myeloid leukemia with FLT3…”
Get full text
Journal Article -
12
Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3mut+ AML ineligible for intensive chemotherapy
Published in Blood (27-10-2022)“…•In patients with FLT3mut+ AML unfit for intensive chemotherapy, CRc rate was higher with GIL + AZA than with AZA.•OS was not significantly different between…”
Get full text
Journal Article -
13
Stress-induced secretion of growth inhibitors : a novel tumor suppressor function of p53
Published in Oncogene (03-09-1998)“…p53 tumor suppressor gene controls cell response to a variety of stresses inducing growth arrest or apoptosis in damaged cells. It largely determines the…”
Get full text
Journal Article -
14
Lisette Model's Explanation: Ralph Steiner, PM, and the Journalistic Frame
Published in Oxford art journal (01-03-2015)Get full text
Journal Article -
15
Training a Sensibility: Notes on American Art and Mass Media
Published in American art (01-06-2013)“…With Bernice Abbot's 1932 exhibition of "Murals by American painters and photographers" at the Museum of Modern Art in New York City, she broached the problem…”
Get full text
Journal Article -
16
Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice
Published in Cancer research (Chicago, Ill.) (01-10-2006)“…Inactivation of p53 function, which frequently occurs in tumors, can significantly modulate tumor cell sensitivity to radiation and chemotherapeutic drugs…”
Get full text
Journal Article -
17
Impact of FLT3 Mutation Clearance after Front-Line Treatment with Gilteritinib Plus Azacitidine, or Gilteritinib or Azacitidine Alone in Patients with Newly Diagnosed AML: Results from the Phase 2/3 Lacewing Trial
Published in Blood (23-11-2021)“…▪ Background: The presence of measurable residual disease (MRD) after achievement of remission with induction therapy is a prognostic marker of relapse risk in…”
Get full text
Journal Article -
18
A Phase 1, Dose-Escalation Study of Gilteritinib Combined with Chemotherapy in Patients Aged 6 Months to <21 Years with FLT3 Internal Tandem Duplication-Positive Relapsed or Refractory AML
Published in Blood (23-11-2021)“…Background: Acute myeloid leukemia (AML) accounts for ~18% of all childhood leukemias (Puumala SE, et al. Pediatr Blood Cancer. 2013;60(5):728-733)…”
Get full text
Journal Article -
19
How to Look at News Pictures in America
Published in American art (01-06-2016)Get full text
Journal Article -
20
Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3 mut+ AML ineligible for intensive chemotherapy
Published in Blood (27-10-2022)“…Treatment results for patients with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-mutated (FLT3mut+) acute myeloid leukemia (AML) ineligible for intensive…”
Get full text
Journal Article