Search Results - "Hill, G H"

Possible in situ formation of meteoritic nanodiamonds in the early Solar System by Bradley, J. P, Dai, Z. R, Joswiak, D. J, Brownlee, D. E, Hill, H. G. M, Genge, M. J

“…Grains of dust that pre-date the Sun provide insights into their formation around other stars and into the early evolution of the Solar System. Nanodiamonds…”
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Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: Molecular and Clinical Markers for the Diagnosis and Management of Type 1 VWD (MCMDM-1VWD) by Haberichter, Sandra L., Castaman, Giancarlo, Budde, Ulrich, Peake, Ian, Goodeve, Anne, Rodeghiero, Francesco, Federici, Augusto B., Batlle, Javier, Meyer, Dominique, Mazurier, Claudine, Goudemand, Jenny, Eikenboom, Jeroen, Schneppenheim, Reinhard, Ingerslev, Jorgen, Vorlova, Zdena, Habart, David, Holmberg, Lars, Lethagen, Stefan, Pasi, John, Hill, Frank G.H., Montgomery, Robert R.

“…The decreased survival of von Willebrand factor (VWF) in plasma has been implicated as a mechanism in a subset of type 1 von Willebrand disease (VWD) patients…”
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Resolving the Inner Cavity of the HD 100546 Disk: A Candidate Young Planetary System? by Grady, C. A, Woodgate, B, Heap, S. R, Bowers, C, Nuth III, J. A, Herczeg, G. J, Hill, H. G. M

“…The inner 100 AU of HD 100546 is studied via far-ultraviolet long-slit spectroscopy with the Hubble Space Telescope Space Telescope Imaging Spectrograph…”
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Unique heterozygous intron 22 inversion band pattern in a haemophilic male detected by long polymerase chain reaction (PCR) by Theophilus, Bimal D M, Enayat, Mohammed S, Green, Peter M, Wilde, Jonathan T, Hill, Frank G H

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Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk‐stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172) by Hill, Frank G. H., Richards, Sue, Gibson, Brenda, Hann, Ian, Lilleyman, John, Kinsey, Sally, Mitchell, Christopher, Harrison, Christine J., Eden, Osborn B.

“…Summary Concern about late adverse effects of cranial radiotherapy (XRT) has led to alternative approaches to eliminate leukaemia from the central nervous…”
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The diagnosis and management of factor VIII and IX inhibitors : A guideline from the UK Haemophilia Centre Doctors' Organization (UKHCDO) by HAY, C. R. M, BAGLIN, T. P, COLLINS, P. W, HILL, F. G. H, KEELING, D. M

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Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV by Darby, Sarah C., Kan, Sau Wan, Spooner, Rosemary J., Giangrande, Paul L.F., Hill, Frank G.H., Hay, Charles R.M., Lee, Christine A., Ludlam, Christopher A., Williams, Michael

“…Since the 1970s, mortality in the hemophilia population has been dominated by human immunodeficiency virus (HIV) and few reports have described mortality in…”
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The R2464C missense mutation in the von Willebrand factor gene causes a novel abnormality of multimer electrophoretic mobility and falls into the subgroup of type 2 von Willebrand disease 'unclassified' by Lester, William A, Guilliatt, Andrea M, Enayat, M Said, Rose, Peter, Hill, Frank G H

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Predictive value of flow cytometric minimal residual disease analysis in childhood acute lymphoblastic leukaemia at the end of remission induction therapy – results from a single UK centre by Motwani, Jayashree, Jesson, Jenny, Sturch, Elaine, Jones, Sue, Eyre, Lisa, Short, Phil, Davies, Paul, Williams, Mike D., Darbyshire, Phil J., Hill, Frank G. H., Lawson, Sarah

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Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor by SADLER, J. E., BUDDE, U., EIKENBOOM, J. C. J., FAVALORO, E. J., HILL, F. G. H., HOLMBERG, L., INGERSLEV, J., LEE, C. A., LILLICRAP, D., MANNUCCI, P. M., MAZURIER, C., MEYER, D., NICHOLS, W. L., NISHINO, M., PEAKE, I. R., RODEGHIERO, F., SCHNEPPENHEIM, R., RUGGERI, Z. M., SRIVASTAVA, A., MONTGOMERY, R. R., FEDERICI, A. B.

“…von Willebrand disease (VWD) is a bleeding disorder caused by inherited defects in the concentration, structure, or function of von Willebrand factor (VWF)…”
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Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia by PEDEN, A., McCARDLE, L., HEAD, M. W., LOVE, S., WARD, H. J. T., COUSENS, S. N., KEELING, D. M., MILLAR, C. M., HILL, F. G. H., IRONSIDE, J. W.

“…All UK patients with bleeding disorders treated with any UK‐sourced pooled factor concentrates between 1980 and 2001 have been informed that they may be at an…”
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Inherited and de novo von Willebrand disease ‘Vicenza’ in UK families with the R1205H mutation: diagnostic pitfalls and new insights by Lester, William A., Guilliatt, Andrea M., Surdhar, Gurcharan K., Enayat, Said M., Wilde, Jonathan T., Willoughby, Sara, Grundy, Pam, Cumming, Anthony M., Collins, Peter W., Hill, Frank G. H.

“…Summary von Willebrand disease (VWD) caused by the R1205H mutation has distinct and reproducible clinical and laboratory features. This report describes the…”
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Light scattering by fluffy Mg–Fe–SiO and C mixtures as cometary analogs (PROGRA 2 experiment) by Hadamcik, E., Renard, J.-B., Rietmeijer, F.J.M., Levasseur-Regourd, A.C., Hill, H.G.M., Karner, J.M., Nuth, J.A.

“…Cometary particles mainly consist of silicates and carbon compounds; they seem to be fluffy aggregates of tiny grains, as found in some IDPs. The linear…”
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6‐Thioguanine‐related Chronic Hepatotoxicity and Variceal Haemorrhage in Children Treated for Acute Lymphoblastic Leukaemia‐A Dual‐centre Experience by Ravikumara, Madhur, Hill, Frank G.H., Wilson, David C., Gillett, Peter M., Thomas, Angela, Brown, R., Darbyshire, Philip J., McKiernan, Patrick J.

“…ABSTRACT Background: 6‐Thioguanine treatment in childhood acute lymphoblastic leukaemia (ALL) has been shown to cause hepatic veno‐occlusive disease, but this…”
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The prevalence of the cysteine1584 variant of von Willebrand factor is increased in type 1 von Willebrand disease: co‐segregation with increased susceptibility to ADAMTS13 proteolysis but not clinical phenotype by Bowen, Derrick J., Collins, Peter W., Lester, Will, Cumming, Anthony M., Keeney, Steven, Grundy, Pamela, Enayat, Saad M., Bolton‐Maggs, Paula H. B., Keeling, David M., Khair, Kate, Campbell Tait, R., Wilde, Jonathon T., John Pasi, K., Hill, Frank G. H.

“…Summary The molecular pathogenesis of type 1 von Willebrand disease (VWD) is uncertain in most patients. We examined 30 type 1 VWD families in the UK…”
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Determining the ages of comets from the fraction of crystalline dust by Nuth, Joseph A, Hill, Hugh G. M, Kletetschka, Gunther

“…The timescale for the accretion of bodies in the disk surrounding a young star depends upon a number of assumptions, but there are few observational…”
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The incidence of factor VIII and factor IX inhibitors in the hemophilia population of the UK and their effect on subsequent mortality, 1977–99 by Darby, S. C., Keeling, D. M., Spooner, R. J. D., Wan Kan, S., Giangrande, P. L. F., Collins, P. W., Hill, F. G. H., Hay, C. R. M.

“…Background: Previous studies of the development of inhibitors and their impact on mortality have been small. Objectives: To examine the development of…”
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Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia by Harrison, Christine J., Moorman, Anthony V., Broadfield, Zoë J., Cheung, Kan L., Harris, Rachel L., Reza Jalali, G., Robinson, Hazel M., Barber, Kerry E., Richards, Sue M., Mitchell, Christopher D., Eden, Tim O. B., Hann, Ian M., Hill, Frank G.H., Kinsey, Sally E., Gibson, Brenda E.S., Lilleyman, John, Vora, Ajay, Goldstone, Anthony H., Franklin, Ian M., Durrant, Jill, Martineau, Mary

“…Summary This study of children and adults with acute lymphoblastic leukaemia (ALL) is the largest series of patients with hypodiploidy (<46 chromosomes) yet…”
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The risk of variant Creutzfeldt-Jakob disease among UK patients with bleeding disorders, known to have received potentially contaminated plasma products by ZAMAN, S. M. A., HILL, F. G. H., PALMER, B., MILLAR, C. M., BONE, A., MOLESWORTH, A. M., CONNOR, N., LEE, C. A., DOLAN, G., WILDE, J. T., GILL, O. N., MAKRIS, M.

“…The risk of variant Creutzfeldt‐Jakob disease (vCJD) from potentially infected plasma products remains unquantified. This risk has been assessed for 787 UK…”
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A new candidate missense mutation (Leu 1657 IIe) in an apparently asymptomatic type 2A (phenotype IIA) von Willebrand disease family by Enayat, M S, Guilliatt, A M, Surdhar, G K, Theophilus, B D, Hill, F G

“…Type 2A von Willebrand disease (VWD) is mostly an autosomal dominantly inherited bleeding disorder characterised by a qualitative defect of von Willebrand…”
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